hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08089.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC2A8 | Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) | 5 | UniProt NCBI |
| SAMM50 | Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3) | 5 | UniProt NCBI |
| MTX2 | Metaxin-2 (Mitochondrial outer membrane import complex protein 2) | 5 | UniProt NCBI |
| IMMT | MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6249 | 8.41624867868e-08 | 0.75 | MTX2 SAMM50 IMMT | MIB complex |
| REAC:R-HSA-8949613 | 5.68914662089e-06 | 0.75 | MTX2 SAMM50 IMMT | Cristae formation |
| GO:0001401 | 8.45465618902e-05 | 0.75 | MTX2 SAMM50 IMMT | SAM complex |
| GO:0140275 | 8.45465618902e-05 | 0.75 | MTX2 SAMM50 IMMT | MIB complex |
| REAC:R-HSA-1592230 | 0.000142992960064 | 0.75 | MTX2 SAMM50 IMMT | Mitochondrial biogenesis |
| GO:0005742 | 0.000437924933217 | 0.75 | MTX2 SAMM50 IMMT | mitochondrial outer membrane translocase complex |
| GO:0098799 | 0.000510886175237 | 0.75 | MTX2 SAMM50 IMMT | outer mitochondrial membrane protein complex |
| GO:0007007 | 0.0037914498893 | 0.75 | MTX2 SAMM50 IMMT | inner mitochondrial membrane organization |
| REAC:R-HSA-1852241 | 0.00474364374959 | 0.75 | MTX2 SAMM50 IMMT | Organelle biogenesis and maintenance |
| KEGG:04137 | 0.0118173906169 | 0.5 | MTX2 SAMM50 | Mitophagy - animal |
| REAC:R-HSA-1268020 | 0.0180511544442 | 0.5 | MTX2 SAMM50 | Mitochondrial protein import |
| GO:0007006 | 0.0378152735667 | 0.75 | MTX2 SAMM50 IMMT | mitochondrial membrane organization |
| CORUM:6132 | 0.049938562206 | 0.25 | IMMT | MINOS complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SAMM50 | MTX2 | 1.0 | 0.958 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM |
| IMMT | MTX2 | 1.0 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt hein () bioplex3_HCT116 fraction boldt_WMM | |
| SAMM50 | IMMT | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| MTX2 | SLC2A8 | 0.97 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SAMM50 | SLC2A8 | 0.97 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IMMT | SLC2A8 | 0.948 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
Related Complexes