hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08098.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EFNB2 | Ephrin-B2 (EPH-related receptor tyrosine kinase ligand 5) (LERK-5) (HTK ligand) (HTK-L) | 5 | UniProt NCBI |
| FAM171A2 | Protein FAM171A2 | 3 | UniProt NCBI |
| RADIL | Ras-associating and dilute domain-containing protein | 5 | UniProt NCBI |
| SDC3 | Syndecan-3 (SYND3) | 5 | UniProt NCBI |
| EPHB3 | Ephrin type-B receptor 3 (EC 2.7.10.1) (EPH-like tyrosine kinase 2) (EPH-like kinase 2) (Embryonic kinase 2) (EK2) (hEK2) (Tyrosine-protein kinase TYRO6) | 5 | UniProt NCBI |
| DIP2B | Disco-interacting protein 2 homolog B (DIP2 homolog B) | 4 | UniProt NCBI |
| DIP2A | Disco-interacting protein 2 homolog A (DIP2 homolog A) (EC 6.2.1.1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3928664 | 0.00455853850403 | 0.285714285714 | EPHB3 EFNB2 | Ephrin signaling |
| REAC:R-HSA-3928662 | 0.0265716665994 | 0.285714285714 | EPHB3 EFNB2 | EPHB-mediated forward signaling |
| REAC:R-HSA-3928665 | 0.0357075146256 | 0.285714285714 | EPHB3 EFNB2 | EPH-ephrin mediated repulsion of cells |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| EFNB2 | SDC3 | 0.986 | 0.134 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| EFNB2 | DIP2A | 0.977 | 0.054 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| EPHB3 | EFNB2 | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM | |
| EFNB2 | DIP2B | 0.972 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| EFNB2 | RADIL | 0.967 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| EFNB2 | FAM171A2 | 0.954 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
| FAM171A2 | DIP2B | 0.947 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
| DIP2B | DIP2A | 0.929 | 0.462 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| FAM171A2 | DIP2A | 0.917 | 0.05 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| EPHB3 | SDC3 | 0.378 | bioplex_WMM bioplex3_WMM WMM_only | |
| EPHB3 | DIP2B | 0.358 | bioplex_WMM bioplex3_WMM WMM_only | |
| EPHB3 | RADIL | 0.3 | bioplex_WMM bioplex3_WMM WMM_only | |
| RADIL | DIP2B | 0.263 | bioplex_WMM bioplex3_WMM WMM_only | |
| SDC3 | FAM171A2 | 0.228 | 0.104 | bioplex_WMM bioplex3_WMM WMM_only |
| SDC3 | DIP2B | 0.215 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only |
| SDC3 | RADIL | 0.188 | bioplex_WMM bioplex3_WMM WMM_only | |
| EPHB3 | DIP2A | 0.131 | bioplex_WMM bioplex3_WMM WMM_only | |
| EPHB3 | FAM171A2 | 0.119 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| RADIL | DIP2A | 0.097 | bioplex_WMM bioplex3_WMM WMM_only | |
| SDC3 | DIP2A | 0.08 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| FAM171A2 | RADIL | 0.079 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes