hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08158.1

Complex Portal: CPX-17666

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
CLASP1	CLIP-associating protein 1 (Cytoplasmic linker-associated protein 1) (Multiple asters homolog 1) (Protein Orbit homolog 1) (hOrbit1)	5	UniProt NCBI
CLASP2	CLIP-associating protein 2 (Cytoplasmic linker-associated protein 2) (Protein Orbit homolog 2) (hOrbit2)	5	UniProt NCBI
MTCL2	Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-428890	0.000190864539041	0.666666666667	CLASP2 CLASP1	Role of ABL in ROBO-SLIT signaling
WP:WP4932	0.00514316015145	0.666666666667	CLASP2 CLASP1	7q11 23 copy number variation syndrome
GO:1903690	0.00842684400117	0.666666666667	CLASP2 CLASP1	negative regulation of wound healing, spreading of epidermal cells
GO:2001197	0.0140440992017	0.666666666667	CLASP2 CLASP1	basement membrane assembly involved in embryonic body morphogenesis
GO:1904259	0.0140440992017	0.666666666667	CLASP2 CLASP1	regulation of basement membrane assembly involved in embryonic body morphogenesis
GO:1904261	0.0140440992017	0.666666666667	CLASP2 CLASP1	positive regulation of basement membrane assembly involved in embryonic body morphogenesis
GO:0045180	0.0140440992017	0.666666666667	CLASP2 CLASP1	basal cortex
GO:0030981	0.0140440992017	0.666666666667	CLASP2 CLASP1	cortical microtubule cytoskeleton
REAC:R-HSA-141444	0.0284248695791	0.666666666667	CLASP2 CLASP1	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
REAC:R-HSA-141424	0.0284248695791	0.666666666667	CLASP2 CLASP1	Amplification of signal from the kinetochores
GO:0090091	0.0294899169624	0.666666666667	CLASP2 CLASP1	positive regulation of extracellular matrix disassembly
GO:0070831	0.0294899169624	0.666666666667	CLASP2 CLASP1	basement membrane assembly
GO:0002162	0.0294899169624	0.666666666667	CLASP2 CLASP1	dystroglycan binding
REAC:R-HSA-69618	0.0392065258044	0.666666666667	CLASP2 CLASP1	Mitotic Spindle Checkpoint
GO:1903689	0.0393180950424	0.666666666667	CLASP2 CLASP1	regulation of wound healing, spreading of epidermal cells
REAC:R-HSA-9648025	0.0429286997388	0.666666666667	CLASP2 CLASP1	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-2500257	0.049233254294	0.666666666667	CLASP2 CLASP1	Resolution of Sister Chromatid Cohesion

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
CLASP1	CLASP2	0.993	0.12		hein_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM treiber_WMM
CLASP1	MTCL2	0.976	0.08		hein_WMM bioplex3_WMM youn_WMM hein () treiber_WMM
CLASP2	MTCL2	0.963	0.022		hein_WMM bioplex3_WMM boldt hein () boldt_WMM

Related Complexes

Genename	Complexes
CLASP1	huMAP3_01699.1 huMAP3_07247.1 huMAP3_08158.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_10808.1 huMAP3_12301.1
CLASP2	huMAP3_02924.1 huMAP3_03180.1 huMAP3_07247.1 huMAP3_08158.1 huMAP3_09810.1 huMAP3_09979.1 huMAP3_10707.1
MTCL2	huMAP3_02924.1 huMAP3_03180.1 huMAP3_07247.1 huMAP3_08158.1 huMAP3_09979.1 huMAP3_10707.1 huMAP3_15214.1