hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08160.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SIM2 | Single-minded homolog 2 (Class E basic helix-loop-helix protein 15) (bHLHe15) | 5 | UniProt NCBI |
| FOXR2 | Forkhead box protein R2 (Forkhead box protein N6) | 4 | UniProt NCBI |
| ARNT | Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta) | 5 | UniProt NCBI |
| MYC | Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3299 | 0.0413734636003 | 0.333333333333 | MYC | let 7 inhibition of ES cell reprogramming |
| WP:WP2249 | 0.0496447587094 | 0.333333333333 | MYC | Metastatic brain tumor |
| CORUM:2649 | 0.0499402709677 | 0.333333333333 | MYC | MYC-DNMT3A-ZBTB17 complex |
| CORUM:2655 | 0.0499402709677 | 0.333333333333 | MYC | MYC-MAX complex |
| CORUM:3052 | 0.0499402709677 | 0.333333333333 | MYC | MYC-MAX complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MYC | FOXR2 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FOXR2 | SIM2 | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SIM2 | ARNT | 0.993 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FOXR2 | ARNT | 0.957 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MYC | SIM2 | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| MYC | ARNT | 0.17 | 0.384 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes