hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08165.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KDM1A | Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2) ([histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A) | 5 | UniProt NCBI |
| EEF1AKMT4-ECE2 | EEF1AKMT4-ECE2 readthrough transcript protein (EC 3.4.24.71) [Includes: Methyltransferase-like region (EC 2.1.1.-); Endothelin-converting enzyme 2 region (EC 3.4.24.71)] | 5 | UniProt NCBI |
| OVOL2 | Transcription factor Ovo-like 2 (hOvo2) (Zinc finger protein 339) | 5 | UniProt NCBI |
| RCOR2 | REST corepressor 2 | 3 | UniProt NCBI |
| HMG20B | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:636 | 0.000204640425412 | 0.4 | KDM1A HMG20B | BHC complex |
| CORUM:620 | 0.000286457379015 | 0.4 | KDM1A HMG20B | CoREST-HDAC complex |
| CORUM:871 | 0.000286457379015 | 0.4 | KDM1A HMG20B | BRAF53-BRCA2 complex |
| CORUM:1492 | 0.000613585186048 | 0.4 | KDM1A HMG20B | BHC110 complex |
| CORUM:633 | 0.000749834781753 | 0.4 | KDM1A HMG20B | anti-BHC110 complex |
| CORUM:626 | 0.00106311089559 | 0.4 | KDM1A HMG20B | LSD1 complex |
| CORUM:632 | 0.00185261424459 | 0.4 | KDM1A HMG20B | Anti-HDAC2 complex |
| REAC:R-HSA-3214815 | 0.0475253950332 | 0.4 | KDM1A HMG20B | HDACs deacetylate histones |
| CORUM:2160 | 0.0498708842806 | 0.2 | KDM1A | AOF2-AR complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HMG20B | KDM1A | 1.0 | 0.236 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HMG20B | RCOR2 | 0.998 | 0.102 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| HMG20B | OVOL2 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EEF1AKMT4-ECE2 | RCOR2 | 0.995 | 0.044 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| EEF1AKMT4-ECE2 | KDM1A | 0.989 | 0.216 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RCOR2 | KDM1A | 0.985 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
| OVOL2 | KDM1A | 0.96 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes