hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08176.1
Complex Portal: CPX-22835
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DECR2 | Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (pDCR) (EC 1.3.1.124) (2,4-dienoyl-CoA reductase 2) (Short chain dehydrogenase/reductase family 17C member 1) | 5 | UniProt NCBI |
| PI4KA | Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha) | 5 | UniProt NCBI |
| HYCC1 | Hyccin (Down-regulated by CTNNB1 protein A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6890 | 2.05032700758e-05 | 0.666666666667 | PI4KA HYCC1 | Phosphatidylinositol 4-kinase complex |
| HP:0030187 | 0.00549749049527 | 0.666666666667 | PI4KA HYCC1 | Titubation |
| HP:0003429 | 0.037868427304 | 0.666666666667 | PI4KA HYCC1 | CNS hypomyelination |
| HP:0002080 | 0.0493566712329 | 0.666666666667 | PI4KA HYCC1 | Intention tremor |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PI4KA | HYCC1 | 0.992 | 0.19 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PI4KA | DECR2 | 0.979 | 0.0466666666667 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| HYCC1 | DECR2 | 0.404 | 0.028 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| DECR2 | huMAP3_08176.1 |
| PI4KA | huMAP3_00134.1 huMAP3_03063.1 huMAP3_08176.1 |
| HYCC1 | huMAP3_00134.1 huMAP3_03063.1 huMAP3_03300.1 huMAP3_08176.1 huMAP3_08206.1 huMAP3_09109.1 |