hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08179.1

Complex Portal: CPX-20873

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
TUBB8	Tubulin beta-8 chain (Tubulin beta 8 class VIII)	5	UniProt NCBI
DNAJA1	DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2)	5	UniProt NCBI
CDC42EP1	Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)	5	UniProt NCBI
TUBB	Tubulin beta chain (Tubulin beta-5 chain)	5	UniProt NCBI
CAD	Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]	5	UniProt NCBI
EML6	Echinoderm microtubule-associated protein-like 6 (EMAP-6) (Echinoderm microtubule-associated protein-like 5-like)	3	UniProt NCBI
RPS27	Small ribosomal subunit protein eS27 (40S ribosomal protein S27) (Metallopan-stimulin 1) (MPS-1)	5	UniProt NCBI
PLD2	Phospholipase D2 (PLD 2) (hPLD2) (EC 3.1.4.4) (Choline phosphatase 2) (PLD1C) (Phosphatidylcholine-hydrolyzing phospholipase D2)	5	UniProt NCBI
TUBB2B	Tubulin beta-2B chain	5	UniProt NCBI
TTC5	Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap)	5	UniProt NCBI
TUBA1A	Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]	5	UniProt NCBI
TUBB4A	Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)	5	UniProt NCBI
TUBA4B	Putative tubulin-like protein alpha-4B (EC 3.6.5.-) (Alpha-tubulin 4B)	3	UniProt NCBI
TUBA1B	Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]	5	UniProt NCBI
TUBB6	Tubulin beta-6 chain (Tubulin beta class V)	5	UniProt NCBI
MADD	MAP kinase-activating death domain protein (Differentially expressed in normal and neoplastic cells) (Insulinoma glucagonoma clone 20) (Rab3 GDP/GTP exchange factor) (RabGEF) (Rab3 GDP/GTP exchange protein) (Rab3GEP)	5	UniProt NCBI
TUBB2A	Tubulin beta-2A chain (Tubulin beta class IIa)	5	UniProt NCBI
TUBB3	Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)	5	UniProt NCBI
TUBA4A	Tubulin alpha-4A chain (EC 3.6.5.-) (Alpha-tubulin 1) (Testis-specific alpha-tubulin) (Tubulin H2-alpha) (Tubulin alpha-1 chain)	5	UniProt NCBI
TBCD	Tubulin-specific chaperone D (Beta-tubulin cofactor D) (tfcD) (SSD-1) (Tubulin-folding cofactor D)	5	UniProt NCBI
CAPS	Calcyphosin (Calcyphosine)	5	UniProt NCBI
ARL2	ADP-ribosylation factor-like protein 2	5	UniProt NCBI
FAS	Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)	5	UniProt NCBI
TCP11L1	T-complex protein 11-like protein 1	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-389977	3.60343837793e-24	0.478260869565	TUBA1B TUBB2A ARL2 TUBA1A TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	Post-chaperonin tubulin folding pathway
REAC:R-HSA-190840	1.31354841693e-22	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
REAC:R-HSA-190872	2.77080173774e-22	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Transport of connexons to the plasma membrane
REAC:R-HSA-9619483	9.75683955714e-21	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Activation of AMPK downstream of NMDARs
REAC:R-HSA-190861	3.90757432962e-20	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Gap junction assembly
REAC:R-HSA-5626467	5.95936137899e-20	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	RHO GTPases activate IQGAPs
REAC:R-HSA-9668328	5.95936137899e-20	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Sealing of the nuclear envelope (NE) by ESCRT-III
REAC:R-HSA-3371497	1.5749790101e-19	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4B TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B DNAJA1	HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
REAC:R-HSA-8955332	1.39626218983e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Carboxyterminal post-translational modifications of tubulin
REAC:R-HSA-9609736	1.39626218983e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Assembly and cell surface presentation of NMDA receptors
WP:WP2359	1.53418522278e-18	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Parkin ubiquitin proteasomal system pathway
REAC:R-HSA-190828	1.87621008762e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Gap junction trafficking
REAC:R-HSA-157858	2.49958588386e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Gap junction trafficking and regulation
REAC:R-HSA-9646399	3.30322431422e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Aggrephagy
REAC:R-HSA-389960	6.35138827648e-18	0.391304347826	TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Formation of tubulin folding intermediates by CCT/TriC
WP:WP2272	9.34526273889e-18	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Pathogenic Escherichia coli infection
REAC:R-HSA-437239	1.19620154676e-17	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Recycling pathway of L1
REAC:R-HSA-6811436	3.00462577837e-17	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	COPI-independent Golgi-to-ER retrograde traffic
REAC:R-HSA-983189	6.97701587879e-17	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Kinesins
REAC:R-HSA-389958	8.6674941513e-17	0.391304347826	TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
REAC:R-HSA-380320	1.05408384916e-16	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Recruitment of NuMA to mitotic centrosomes
REAC:R-HSA-391251	1.35979005947e-16	0.478260869565	TUBA1B TUBB2A ARL2 TUBA1A TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	Protein folding
KEGG:04540	2.5344941775e-16	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Gap junction
REAC:R-HSA-2995410	7.15440004217e-16	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Nuclear Envelope (NE) Reassembly
REAC:R-HSA-438064	8.38110817064e-16	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Post NMDA receptor activation events
REAC:R-HSA-1445148	9.79367778878e-16	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Translocation of SLC2A4 (GLUT4) to the plasma membrane
REAC:R-HSA-9648025	1.44751475806e-15	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	EML4 and NUDC in mitotic spindle formation
REAC:R-HSA-9663891	2.37589470262e-15	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Selective autophagy
REAC:R-HSA-8852276	2.73365682719e-15	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	The role of GTSE1 in G2/M progression after G2 checkpoint
REAC:R-HSA-2500257	3.15964768375e-15	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-442755	4.70006590764e-15	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-5663220	8.49400408937e-15	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	RHO GTPases Activate Formins
REAC:R-HSA-68877	8.68719583987e-15	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Mitotic Prometaphase
GO:0005200	1.6338299662e-14	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	structural constituent of cytoskeleton
REAC:R-HSA-6811434	2.28209974907e-14	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	COPI-dependent Golgi-to-ER retrograde traffic
REAC:R-HSA-6807878	3.17834448241e-14	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	COPI-mediated anterograde transport
REAC:R-HSA-373760	5.97271714157e-14	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	L1CAM interactions
KEGG:04145	1.62995829248e-13	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Phagosome
REAC:R-HSA-2132295	2.47068731466e-13	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	MHC class II antigen presentation
REAC:R-HSA-9609690	3.20718450772e-13	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	HCMV Early Events
REAC:R-HSA-2467813	3.56639008393e-13	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Separation of Sister Chromatids
GO:0005525	3.57952247611e-13	0.521739130435	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	GTP binding
REAC:R-HSA-5617833	4.81092510929e-13	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Cilium Assembly
REAC:R-HSA-69275	4.81092510929e-13	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	G2/M Transition
REAC:R-HSA-8856688	5.29753220892e-13	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Golgi-to-ER retrograde transport
REAC:R-HSA-1632852	5.29753220892e-13	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Macroautophagy
REAC:R-HSA-453274	5.41039178355e-13	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Mitotic G2-G2/M phases
GO:0005874	1.16987510713e-12	0.565217391304	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TCP11L1 TUBB3 TUBB2B TUBA4B	microtubule
REAC:R-HSA-390466	1.21528094699e-12	0.391304347826	TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Chaperonin-mediated protein folding
KEGG:04814	1.31714066107e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Motor proteins
GO:0032561	1.43332329082e-12	0.521739130435	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	guanyl ribonucleotide binding
GO:0019001	1.52522261749e-12	0.521739130435	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	guanyl nucleotide binding
KEGG:05130	1.58686469562e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Pathogenic Escherichia coli infection
REAC:R-HSA-9612973	1.67717957689e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Autophagy
REAC:R-HSA-9609646	1.80276789544e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	HCMV Infection
REAC:R-HSA-5620924	1.87923247541e-12	0.347826086957	TUBA1B TUBB6 TUBA1A TUBA4A TUBB2A TUBB4A TUBB3 TUBB2B	Intraflagellar transport
REAC:R-HSA-199977	1.93673423163e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	ER to Golgi Anterograde Transport
REAC:R-HSA-389957	2.4414126229e-12	0.304347826087	TUBB6 TUBA1A TUBA4A TUBB2A TUBB4A TUBB3 TUBB2B	Prefoldin mediated transfer of substrate to CCT/TriC
REAC:R-HSA-68882	3.028336513e-12	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Mitotic Anaphase
REAC:R-HSA-2555396	3.18230091326e-12	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Mitotic Metaphase and Anaphase
REAC:R-HSA-983231	5.01734300293e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Factors involved in megakaryocyte development and platelet production
REAC:R-HSA-112314	5.35198245835e-12	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Neurotransmitter receptors and postsynaptic signal transmission
REAC:R-HSA-948021	1.26688153454e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Transport to the Golgi and subsequent modification
REAC:R-HSA-1852241	3.06270787222e-11	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Organelle biogenesis and maintenance
REAC:R-HSA-68886	3.36651146598e-11	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	M Phase
KEGG:05132	3.46338241965e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Salmonella infection
REAC:R-HSA-6811442	4.05864658445e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Intra-Golgi and retrograde Golgi-to-ER traffic
KEGG:05012	6.35453784887e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Parkinson disease
REAC:R-HSA-112315	6.75102046979e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Transmission across Chemical Synapses
REAC:R-HSA-195258	6.87052563395e-11	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	RHO GTPase Effectors
KEGG:05020	8.48968613433e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Prion disease
WP:WP5124	9.59294277105e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Alzheimer 39 s disease
WP:WP2059	9.59294277105e-11	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Alzheimer 39 s disease and miRNA effects
KEGG:05016	2.32007257237e-10	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Huntington disease
GO:0035639	3.0483744867e-10	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	purine ribonucleoside triphosphate binding
GO:0099513	3.24273279105e-10	0.565217391304	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TCP11L1 TUBB3 TUBB2B TUBA4B	polymeric cytoskeletal fiber
REAC:R-HSA-194315	3.89588164424e-10	0.565217391304	TUBB8 TUBA1B TUBB2A TUBB6 PLD2 TUBA1A RPS27 TUBA4A CDC42EP1 TUBB4A TUBB3 TUBB2B TUBA4B	Signaling by Rho GTPases
REAC:R-HSA-9716542	5.15062620965e-10	0.565217391304	TUBB8 TUBA1B TUBB2A TUBB6 PLD2 TUBA1A RPS27 TUBA4A CDC42EP1 TUBB4A TUBB3 TUBB2B TUBA4B	Signaling by Rho GTPases, Miro GTPases and RHOBTB3
REAC:R-HSA-5610787	7.8312876995e-10	0.347826086957	TUBA1B TUBB6 TUBA1A TUBA4A TUBB2A TUBB4A TUBB3 TUBB2B	Hedgehog 'off' state
REAC:R-HSA-69278	1.26843568472e-09	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Cell Cycle, Mitotic
KEGG:05014	1.36263123183e-09	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Amyotrophic lateral sclerosis
GO:0032555	1.58929387922e-09	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	purine ribonucleotide binding
REAC:R-HSA-446203	1.86958190006e-09	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Asparagine N-linked glycosylation
GO:0032553	1.97074512047e-09	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	ribonucleotide binding
KEGG:05010	2.19221664085e-09	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Alzheimer disease
GO:0000226	2.6332717545e-09	0.565217391304	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	microtubule cytoskeleton organization
REAC:R-HSA-112316	3.12060863513e-09	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Neuronal System
REAC:R-HSA-5358351	4.74397271289e-09	0.347826086957	TUBA1B TUBB6 TUBA1A TUBA4A TUBB2A TUBB4A TUBB3 TUBB2B	Signaling by Hedgehog
GO:0017076	7.69096027516e-09	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	purine nucleotide binding
GO:0099512	1.2571313289e-08	0.565217391304	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TCP11L1 TUBB3 TUBB2B TUBA4B	supramolecular fiber
REAC:R-HSA-422475	1.36716960942e-08	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Axon guidance
REAC:R-HSA-1640170	1.42817129491e-08	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Cell Cycle
GO:0099081	1.47454368696e-08	0.565217391304	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TCP11L1 TUBB3 TUBB2B TUBA4B	supramolecular polymer
KEGG:05022	1.51352925295e-08	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B	Pathways of neurodegeneration - multiple diseases
REAC:R-HSA-9675108	2.02640841485e-08	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Nervous system development
HP:0025102	2.90944945734e-08	0.173913043478	TUBB2B TUBB3 TUBB TUBA1A	Dysgenesis of the basal ganglia
REAC:R-HSA-9824446	3.74416962756e-08	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Viral Infection Pathways
GO:0000166	4.53770952217e-08	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	nucleotide binding
GO:1901265	4.63231616693e-08	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	nucleoside phosphate binding
REAC:R-HSA-2262752	5.18070003503e-08	0.521739130435	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBA4B TUBB3 TUBB2B DNAJA1	Cellular responses to stress
GO:0015630	5.44247136992e-08	0.652173913043	TUBB8 TUBA1B TUBB2A ARL2 TCP11L1 TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TUBA4B TUBB3 TUBB2B DNAJA1	microtubule cytoskeleton
REAC:R-HSA-8953897	5.79134683817e-08	0.521739130435	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBA4B TUBB3 TUBB2B DNAJA1	Cellular responses to stimuli
CORUM:6713	1.07739615662e-07	0.130434782609	ARL2 TUBB TBCD	TBCD-ARL2-tubulin(beta) complex
CORUM:6715	1.07739615662e-07	0.130434782609	ARL2 TUBB TBCD	TBCD-ARL2-tubulin(beta)-TBCE complex
CORUM:6703	1.07739615662e-07	0.130434782609	TBCD TUBB TUBA1A	TBCD-tubulin(alpha)-tubulin(beta) complex
GO:1901363	1.09003524552e-07	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	heterocyclic compound binding
GO:0005198	1.3360754344e-07	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	structural molecule activity
GO:0097367	1.59132960066e-07	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	carbohydrate derivative binding
GO:0007010	1.82210658817e-07	0.652173913043	TUBB8 TUBA1B TUBB2A TUBB6 PLD2 TUBA1A ARL2 TUBB TUBA4A CDC42EP1 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	cytoskeleton organization
GO:0007017	2.059694347e-07	0.565217391304	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	microtubule-based process
REAC:R-HSA-5663205	4.0250479826e-07	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Infectious disease
REAC:R-HSA-109582	7.95932795247e-07	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Hemostasis
GO:0005856	1.10255437424e-06	0.695652173913	TUBB8 TUBA1B TUBB2A TUBB6 ARL2 TCP11L1 TUBA1A TUBB TUBA4A CDC42EP1 TBCD TUBB4A TUBA4B TUBB3 TUBB2B DNAJA1	cytoskeleton
GO:0045171	1.17505406339e-06	0.304347826087	TUBB8 TUBB6 TUBB TUBB2A TUBB4A TUBB3 TUBB2B	intercellular bridge
GO:0043168	1.42306028057e-06	0.565217391304	TUBB8 TUBA1B TUBB2A CAD TUBA1A ARL2 TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	anion binding
REAC:R-HSA-199991	1.84751563797e-06	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Membrane Trafficking
REAC:R-HSA-5653656	3.11025015968e-06	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Vesicle-mediated transport
GO:0099080	3.64201975817e-06	0.565217391304	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TCP11L1 TUBB3 TUBB2B TUBA4B	supramolecular complex
HP:0020214	4.25571481866e-06	0.130434782609	TUBB2B TUBA1A TUBB3	Startle-induced seizure
REAC:R-HSA-1266738	5.80303956651e-06	0.478260869565	TUBB8 TUBA1B TUBB2A TUBA1A RPS27 TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Developmental Biology
REAC:R-HSA-1280218	7.55673753515e-06	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Adaptive Immune System
GO:0000278	8.0300850543e-06	0.521739130435	TUBB8 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	mitotic cell cycle
GO:0043167	1.54117934197e-05	0.652173913043	TUBB8 TUBA1B TUBB2A CAD CAPS TUBA1A ARL2 RPS27 TUBA4A TUBB6 TUBB4A TUBB TUBB3 TUBB2B TUBA4B	ion binding
HP:0012502	1.70053843986e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormality of the internal capsule
GO:0007049	2.17875794116e-05	0.608695652174	TUBB8 TUBA1B TUBB2A ARL2 MADD TUBA1A TUBB TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	cell cycle
HP:0001491	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Congenital fibrosis of extraocular muscles
HP:0001477	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Compensatory chin elevation
HP:0025309	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal pupil shape
HP:0025721	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Limited vertical extraocular movement
HP:0030534	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal best corrected visual acuity test
HP:3000072	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal levator palpebrae superioris morphology
HP:0012241	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Levator palpebrae superioris atrophy
HP:0007831	4.24698192546e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Nonprogressive restrictive external ophthalmoplegia
REAC:R-HSA-162582	7.04314590397e-05	0.608695652174	TUBB8 TUBA1B TUBB2A TUBB6 PLD2 TUBA1A ARL2 RPS27 TUBA4A CDC42EP1 TUBB4A TUBB3 TUBB2B TUBA4B	Signal Transduction
CORUM:6697	7.49713811273e-05	0.0869565217391	ARL2 TBCD	ARL2-TBCD complex
CORUM:6455	7.49713811273e-05	0.0869565217391	ARL2 TBCD	ARL2-TBCD complex
GO:0036094	7.53547154418e-05	0.652173913043	TUBB8 TUBA1B TUBB2A CAD CAPS TUBA1A ARL2 RPS27 TUBA4A TUBB6 TUBB4A TUBB TUBB3 TUBB2B TUBA4B	small molecule binding
HP:0032398	8.48524458287e-05	0.130434782609	TUBB2B TUBA1A TUBB3	Dysgyria
REAC:R-HSA-392499	8.6204824348e-05	0.565217391304	TUBB8 TUBA1B TUBB2A ARL2 TUBA1A RPS27 TUBA4A TUBB6 TBCD TUBB4A TUBB3 TUBB2B TUBA4B	Metabolism of proteins
HP:0002365	0.000148346231127	0.217391304348	TUBB2B TUBB3 TUBB TUBB2A TUBA1A	Hypoplasia of the brainstem
HP:0007362	0.000148346231127	0.217391304348	TUBB2B TUBB3 TUBB TUBB2A TUBA1A	Aplasia/Hypoplasia of the brainstem
GO:0072686	0.000167322882296	0.304347826087	TUBB8 TUBB6 TUBB TUBB2A TUBB4A TUBB3 TUBB2B	mitotic spindle
REAC:R-HSA-1643685	0.000173733193753	0.521739130435	TUBB8 TUBB3 TUBA1B TUBB2A TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B TUBA4B	Disease
HP:0000542	0.000237099331014	0.130434782609	TUBB2B TUBA1A TUBB3	Impaired ocular adduction
HP:0008049	0.000355283929037	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormality of the extraocular muscles
HP:0025186	0.000355283929037	0.130434782609	TUBB2B TUBA1A TUBB3	Marcus Gunn jaw winking synkinesis
HP:0011347	0.000355283929037	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormality of ocular abduction
REAC:R-HSA-168256	0.000691244613432	0.521739130435	TUBB8 TUBA1B TUBB2A PLD2 TUBA1A TUBB TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Immune System
HP:0009916	0.000927643105413	0.130434782609	TUBB2B TUBA1A TUBB3	Anisocoria
HP:0032466	0.000927643105413	0.130434782609	TUBB2B TUBA1A TUBB3	Aplasia of the olfactory bulb
REAC:R-HSA-380259	0.00101566394749	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Loss of Nlp from mitotic centrosomes
REAC:R-HSA-380284	0.00101566394749	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Loss of proteins required for interphase microtubule organization from the centrosome
HP:0007941	0.00120469823386	0.130434782609	TUBB2B TUBA1A TUBB3	Limited extraocular movements
REAC:R-HSA-8854518	0.00121448380754	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	AURKA Activation by TPX2
HP:0002539	0.00138613911624	0.173913043478	TUBB2B TUBB3 TUBB TUBB2A	Cortical dysplasia
CORUM:1400	0.00156687269854	0.0869565217391	TUBB TUBA4A	ASCOM complex
HPA:0461423	0.00158841306721	0.173913043478	TUBA4A TUBB2A TUBA1A TUBA1B	skin 1; eccrine glands[High]
HP:0001338	0.00162085465013	0.173913043478	TUBB2B TUBB3 TUBB TUBA1A	Partial agenesis of the corpus callosum
HPA:0471423	0.00169859067572	0.130434782609	TUBA4A TUBA1A TUBA1B	skin 2; eccrine glands[High]
HP:0030211	0.0019126330519	0.130434782609	TUBB2B TUBA1A TUBB3	Slow pupillary light response
HP:0001180	0.0019126330519	0.130434782609	TUBB2B TUBA1A TUBB3	Hand oligodactyly
REAC:R-HSA-380270	0.00198519494852	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Recruitment of mitotic centrosome proteins and complexes
REAC:R-HSA-380287	0.00198519494852	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Centrosome maturation
HP:0002363	0.00212367860039	0.260869565217	TUBB TUBA1A TUBB2A TUBB3 TUBB2B TBCD	Abnormal brainstem morphology
HP:0001357	0.00229729735681	0.217391304348	TUBB2B TBCD TUBB3 TUBA1A MADD	Plagiocephaly
REAC:R-HSA-597592	0.00232173380868	0.434782608696	TUBB8 TUBA1B TUBB2A TUBA1A TUBA4A TUBB6 TUBB4A TUBB3 TUBB2B TUBA4B	Post-translational protein modification
HP:0031705	0.00235159379676	0.130434782609	TUBB2B TUBA1A TUBB3	Compensatory head posture
REAC:R-HSA-2565942	0.00254417806271	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Regulation of PLK1 Activity at G2/M Transition
HP:0031882	0.002852575954	0.130434782609	TUBB2B TUBA1A TUBB3	Agyria
HP:0020207	0.002852575954	0.130434782609	TUBB2B TUBA1A TUBB3	Reflex seizure
HPA:0500703	0.00371740422391	0.217391304348	TUBA4A TUBB3 TUBA1B TUBB TUBA1A	soft tissue 1; peripheral nerve[High]
REAC:R-HSA-5620912	0.00400046027085	0.173913043478	TUBA4A TUBB4A TUBB TUBA1A	Anchoring of the basal body to the plasma membrane
HP:0030532	0.00405658098876	0.130434782609	TUBB2B TUBA1A TUBB3	Visual acuity test abnormality
HP:0000473	0.0047061247542	0.173913043478	TUBB2B TUBB3 TUBA1A TUBB4A	Torticollis
HP:0030588	0.00476755014475	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal visual field test
HP:0000616	0.00555643335806	0.130434782609	TUBB2B TUBA1A TUBB3	Miosis
HP:0011006	0.00558299687191	0.173913043478	TUBB2B TUBB3 TUBA1A TUBB4A	Abnormal morphology of the musculature of the neck
HP:0009380	0.00693344461701	0.173913043478	TUBB2B TUBB3 RPS27 TUBA1A	Aplasia of the fingers
GO:0006996	0.00758145935168	0.695652173913	TUBB8 TUBA1B TUBB2A TUBB6 PLD2 RPS27 ARL2 TUBB TUBA4A CDC42EP1 TBCD TUBA1A TUBB3 TUBB2B TUBA4B TUBB4A	organelle organization
HP:0011097	0.0077618171038	0.217391304348	TUBB2B TBCD TUBB3 TUBA1A TUBB2A	Epileptic spasm
HPA:0461493	0.00836246438247	0.173913043478	TUBA4A TUBB2A TUBA1A TUBA1B	skin 1; vascular mural cells[High]
HP:0007695	0.00842979799021	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal pupillary light reflex
HPA:0100212	0.00942729819126	0.521739130435	TUBA1B TUBB2A PLD2 TUBB TUBA1A TUBA4A TUBB6 TUBB4A TCP11L1 TUBB3 TUBB2B TTC5	cerebral cortex; neuropil[>=Medium]
HP:0000006	0.00994669825134	0.478260869565	TUBB8 TUBB3 TUBB2A ARL2 TUBA1A TUBB TUBA4A TUBB6 TUBB4A RPS27 TUBB2B	Autosomal dominant inheritance
HPA:0570813	0.0122129285017	0.391304347826	TUBB3 TUBB2A CAD TUBB TUBB6 TUBB4A PLD2 TUBB2B ARL2	testis; spermatogonia cells[High]
GO:0005819	0.0138487235364	0.304347826087	TUBB8 TUBB6 TUBB TUBB2A TUBB4A TUBB3 TUBB2B	spindle
HP:0002536	0.0141611130931	0.260869565217	TUBA1A TUBB TUBB2A TUBB3 TUBB2B TTC5	Abnormal cortical gyration
HP:0000577	0.0155017835496	0.173913043478	TUBB2B TUBB3 TUBA1A MADD	Exotropia
HPA:0461482	0.0165069868821	0.173913043478	TUBA4A ARL2 TUBA1A TUBA1B	skin 1; sebaceous glands[>=Medium]
HP:0040327	0.018587245017	0.130434782609	TUBB2B TUBA1A TUBB3	Abnormal morphology of the olfactory bulb
HP:0000657	0.0190790522395	0.173913043478	TUBB2B TUBB3 TUBA1A TUBB4A	Oculomotor apraxia
HP:0012179	0.0214975526755	0.173913043478	TUBB2B TUBB3 TUBA1A TUBB4A	Craniofacial dystonia
HP:0025668	0.0224485578935	0.304347826087	TUBB3 MADD TUBA1A TUBB TUBB4A RPS27 TUBB2B	Abnormal neck morphology
HP:0012165	0.0225147919734	0.130434782609	TUBB2B TUBA1A TUBB3	Oligodactyly
HP:0020049	0.0250643227665	0.173913043478	TUBB2B TUBB3 TUBA1A MADD	Exodeviation
HPA:0461422	0.0274775879593	0.173913043478	TUBA4A TUBB2A TUBA1A TUBA1B	skin 1; eccrine glands[>=Medium]
HPA:0471422	0.0279037520979	0.130434782609	TUBA4A TUBA1A TUBA1B	skin 2; eccrine glands[>=Medium]
HPA:0470673	0.0291093908021	0.217391304348	TUBA4A TUBB2A TUBA1A ARL2 TUBA1B	skin 2; melanocytes[High]
HPA:0461492	0.0299294057755	0.173913043478	TUBA4A TUBB2A TUBA1A TUBA1B	skin 1; vascular mural cells[>=Medium]
HPA:0471492	0.031212993996	0.173913043478	TUBA4A TUBB2A TUBA1A TUBA1B	skin 2; vascular mural cells[>=Medium]
HPA:0570763	0.0321092104377	0.304347826087	TUBB6 ARL2 TUBB TUBB2A TUBB4A TUBB3 TUBB2B	testis; pachytene spermatocytes[High]
HP:0004373	0.0334801144133	0.173913043478	TUBB2B TUBB3 TUBA1A TUBB4A	Focal dystonia
HP:0000464	0.0345255080794	0.304347826087	TUBB3 MADD TUBA1A TUBB TUBB4A RPS27 TUBB2B	Abnormality of the neck
HPA:0570793	0.0362216665102	0.304347826087	CDC42EP1 TUBB TUBB6 TUBB2A TUBB4A TUBB3 TUBB2B	testis; round or early spermatids[High]
HPA:0461481	0.0367487179991	0.173913043478	TUBA4A ARL2 TUBA1A TUBA1B	skin 1; sebaceous glands[>=Low]
HPA:0471402	0.0403543280617	0.130434782609	TUBA4A TUBA1A TUBA1B	skin 2; cells in corneal layer[>=Medium]
HP:0002079	0.0411849468778	0.260869565217	TUBB TUBA1A TUBB2A TUBB3 TUBB2B TBCD	Hypoplasia of the corpus callosum
HPA:0461483	0.0435357301852	0.130434782609	TUBA4A TUBA1A TUBA1B	skin 1; sebaceous glands[High]
HP:0002269	0.0452603305335	0.260869565217	TUBA1A TUBB TUBB2A TUBB3 TUBB2B TTC5	Abnormality of neuronal migration
HPA:0470202	0.0452900909846	0.260869565217	TUBA1B ARL2 TUBA4A TUBB TUBB2A TUBA1A	skin 2; endothelial cells[>=Medium]
HP:0008527	0.0469378194774	0.130434782609	TUBB2B TUBA1A TUBB3	Congenital sensorineural hearing impairment
HPA:0461443	0.0473918352996	0.217391304348	TUBA4A TUBB2A TUBA1B TUBB TUBA1A	skin 1; fibrohistiocytic cells[High]
HP:0001320	0.0496222622992	0.217391304348	TUBB2B TUBB3 TUBB TUBB2A TUBA1A	Cerebellar vermis hypoplasia
HPA:0471472	0.0499647851127	0.260869565217	TUBA1B ARL2 TUBA4A TUBB TUBB2A TUBA1A	skin 2; lymphocytes[>=Medium]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ARL2	TBCD	1.0	0.2
DNAJA1	TUBB	0.999	0.374
TUBB	TBCD	0.999	0.4
TCP11L1	TUBB	0.999	0.204105263158
TUBB2A	TUBB6	0.999	0.526	structurally_consistent (dimer)
ARL2	TUBB	0.998	0.098
TUBB2B	TBCD	0.998	0.286	structurally_consistent (dimer)
TCP11L1	TUBB2B	0.998	0.162	structurally_consistent (dimer)
TUBB	CAD	0.998	0.352
TUBB8	TUBB	0.997	0.534	structurally_consistent (dimer)
TUBB2B	FAS	0.997	0.166
TUBB2A	CDC42EP1	0.996	0.192703448276
TUBB2A	TUBB8	0.996	0.33	structurally_consistent (dimer)
TUBB6	TUBB	0.996	0.982	mutually_exclusive (Q9BQE3)
TUBB3	TUBB6	0.996	0.308	mutually_exclusive (Q9BQE3)
TUBB2A	TUBB4A	0.996	0.684	structurally_consistent (dimer)
TUBA1B	TUBB	0.995
TCP11L1	TUBB3	0.995	0.086
CAPS	TUBB2B	0.995	0.09
TUBB2A	FAS	0.995	0.204	structurally_consistent (P04350) structurally_consistent (dimer)
TUBB3	TUBB	0.995	0.394	mutually_exclusive (Q9BQE3)
TUBB2A	TBCD	0.995	0.148
TUBB4A	TBCD	0.993	0.3
MADD	TUBA4A	0.993	0.138
TCP11L1	TTC5	0.993	0.04
DNAJA1	TUBA1B	0.993		mutually_exclusive (P68366)
TUBB2A	TUBB	0.993	0.626	structurally_consistent (dimer)
CDC42EP1	TUBB4A	0.993	0.284
PLD2	TUBB	0.992	0.516
TUBB	TUBB4A	0.992	0.938	structurally_consistent (dimer)
TUBB6	TUBB4A	0.992	0.798
TUBB	FAS	0.992	0.112	mutually_exclusive (P04350)
ARL2	TUBB2B	0.991	0.244	structurally_consistent (dimer)
TUBB3	TUBA1A	0.991		structurally_consistent (dimer)
TCP11L1	TUBB4A	0.991	0.138
TUBB2A	TTC5	0.991	0.188	structurally_consistent (dimer)
RPS27	TUBB6	0.99	0.256
TUBB2B	TTC5	0.99	0.184
RPS27	TUBB	0.99	0.49	structurally_consistent (Q3ZCM7)
TUBB2A	TUBB3	0.99	0.38	structurally_consistent (dimer)
TUBB2A	ARL2	0.989	0.164
TUBB4A	TUBB2B	0.988	0.650344827586
DNAJA1	TUBB3	0.988	0.32
CDC42EP1	TUBB	0.988	0.358
TUBB2A	TUBA4A	0.987	0.372
TUBB	TTC5	0.985	0.236
TUBB3	CAD	0.984	0.332
TUBB2A	TCP11L1	0.983	0.106	structurally_consistent (dimer)
TUBA1A	TUBB4A	0.982
TUBA1A	TUBA4A	0.979
TUBB3	TUBB2B	0.979	0.398	structurally_consistent (dimer)
TUBB8	TUBB2B	0.979	0.284	structurally_consistent (dimer)
TUBA1A	TUBB	0.979
TUBA1B	TUBB6	0.977
TUBB6	TUBB2B	0.976	0.63	structurally_consistent (dimer)
TCP11L1	TUBA4A	0.975	0.11	structurally_consistent (dimer)
TUBB6	FAS	0.975	0.224768
RPS27	TUBB4A	0.975	0.264	structurally_consistent (Q3ZCM7)
TUBA4A	TUBB4A	0.975	0.548
TUBB8	TUBB6	0.973	0.546	structurally_consistent (dimer)
CDC42EP1	TUBB2B	0.973	0.146
TUBB3	TUBA4A	0.971	0.394	structurally_consistent (dimer)
TUBB8	TUBA1A	0.971		structurally_consistent (dimer)
TUBB3	EML6	0.97
TUBB8	TUBB4A	0.969	0.554	structurally_consistent (dimer)
DNAJA1	TUBA1A	0.968
TUBA1B	TUBA4A	0.968		structurally_consistent (dimer)
TUBA1A	TUBA1B	0.967
TUBB2A	TUBA1A	0.966		structurally_consistent (dimer)
MADD	TUBB2A	0.966	0.116
TUBB6	TTC5	0.966	0.198
TUBB8	TUBB3	0.965	0.304
TUBB8	CDC42EP1	0.965	0.146
TUBB	TUBA4A	0.963	0.72
MADD	TUBB8	0.958	0.246
RPS27	TUBA1A	0.957
FAS	TBCD	0.956	0.149666666667
CAPS	TUBB6	0.956	0.3
EML6	TUBB2B	0.953
TUBA4A	TTC5	0.952	0.202	structurally_consistent (dimer)
CAPS	TUBB	0.952	0.306608695652
DNAJA1	TUBB8	0.95	0.30875
TUBB3	FAS	0.948	0.22
TUBB4A	FAS	0.947	0.164609230769	structurally_consistent (dimer)
RPS27	TUBB8	0.947	0.368	structurally_consistent (dimer)
TUBB2A	CAPS	0.947	0.138	structurally_consistent (dimer)
CDC42EP1	TUBB3	0.945	0.186
TCP11L1	CDC42EP1	0.943	0.106
TUBB2A	TUBB2B	0.94	0.47	structurally_consistent (dimer)
TCP11L1	TUBB6	0.938	0.152
RPS27	CAD	0.934	0.162
ARL2	TTC5	0.934	0.064
TUBB3	TUBB4A	0.933	0.454	structurally_consistent (dimer)
TCP11L1	ARL2	0.932	0.052
CDC42EP1	TTC5	0.93	0.078
TUBB8	TBCD	0.927	0.31
CDC42EP1	TUBA1A	0.925
DNAJA1	PLD2	0.92	0.096
TUBA1A	TTC5	0.92
ARL2	TUBB4A	0.919	0.188
TCP11L1	TUBA1A	0.916
TUBB3	CAPS	0.915	0.142
RPS27	TUBA4A	0.908	0.377298245614	structurally_consistent (Q3ZCM7) structurally_consistent (dimer)
ARL2	FAS	0.906	0.166
PLD2	TUBA4A	0.904	0.206
TUBB3	TUBA1B	0.9		structurally_consistent (dimer)
TTC5	FAS	0.899	0.11
TUBB6	TUBA4A	0.895	0.636	structurally_consistent (dimer)
TUBB	TUBB2B	0.895	0.719
MADD	TUBB3	0.893	0.064
DNAJA1	TUBA4A	0.892	0.352	structurally_consistent (dimer)
ARL2	TUBB8	0.888	0.362	structurally_consistent (dimer)
CDC42EP1	TUBB6	0.886	0.226042553191
PLD2	CAD	0.88	0.232
DNAJA1	TUBB6	0.867	0.298
DNAJA1	TUBB4A	0.866	0.22
TUBB2A	TUBA1B	0.864
MADD	TUBB4A	0.864	0.142
TUBB8	CAPS	0.859	0.174
CDC42EP1	TUBA4A	0.859	0.252
TUBB2A	PLD2	0.829	0.212
DNAJA1	RPS27	0.823	0.238	structurally_consistent (P68366)
CAPS	TUBB4A	0.812	0.18
MADD	TUBB	0.811	0.263846153846
TUBA1A	TUBB6	0.805
MADD	TUBA1A	0.798
TCP11L1	TBCD	0.792	0.048	structurally_consistent (Q9BVA1)
TUBB8	TUBA4A	0.783	0.586	structurally_consistent (dimer)
TUBB3	TTC5	0.775	0.170162601626
TCP11L1	TUBB8	0.764	0.184
TUBB8	TTC5	0.759	0.172	mutually_exclusive (Q13885)
TUBB3	TBCD	0.752	0.13	structurally_consistent (Q9BVA1)
CDC42EP1	TUBA1B	0.751
ARL2	TUBB3	0.742	0.343173015
TUBA1B	CAD	0.74
TTC5	TBCD	0.739	0.036
MADD	CDC42EP1	0.738	0.068
MADD	FAS	0.725	0.038
CAD	TUBA4A	0.723	0.424
TUBB2A	DNAJA1	0.722	0.16
ARL2	TUBB6	0.716	0.1803
TUBA4A	TUBB2B	0.712	0.396
TUBA1A	CAD	0.692
MADD	PLD2	0.674	0.136
MADD	TCP11L1	0.655	0.066
PLD2	TUBB4A	0.652	0.240861111111
MADD	TUBB6	0.633	0.198
RPS27	TUBA1B	0.628
RPS27	TUBB3	0.619	0.258
TUBB4A	TTC5	0.614	0.312888888889
PLD2	TUBA1B	0.606
TCP11L1	FAS	0.604	0.112
TUBB8	EML6	0.599
MADD	TBCD	0.592	0.062
TUBB2A	CAD	0.591	0.314
TUBB2A	RPS27	0.587	0.17
ARL2	CDC42EP1	0.586	0.082
RPS27	TUBB2B	0.584	0.358	structurally_consistent (Q3ZCM7)
ARL2	PLD2	0.534	0.074
PLD2	TUBB8	0.528	0.208
PLD2	TUBA1A	0.521
CAPS	TUBA4A	0.514	0.176
TCP11L1	DNAJA1	0.51	0.084
DNAJA1	CAD	0.506	0.23
RPS27	TBCD	0.5	0.282
TUBB8	CAD	0.494	0.222
TUBB8	TUBA1B	0.467
CAD	TUBB2B	0.445	0.324
MADD	TTC5	0.443	0.098
PLD2	TTC5	0.439	0.154
DNAJA1	TUBB2B	0.435	0.302
TUBA1B	TUBB4A	0.432
TUBA1A	CAPS	0.429
PLD2	TUBB2B	0.416	0.282405405405
TUBA1A	TUBB2B	0.415
TCP11L1	CAD	0.395	0.058
MADD	TUBB2B	0.389	0.206
EML6	CAPS	0.378
CAD	TUBB4A	0.353	0.294
RPS27	CDC42EP1	0.342	0.186
PLD2	TUBB3	0.342	0.256764705882
MADD	CAD	0.334	0.12
EML6	TUBB6	0.307
ARL2	CAPS	0.303	0.062
DNAJA1	CDC42EP1	0.301	0.174
ARL2	EML6	0.3
TUBA1B	TBCD	0.288
PLD2	TBCD	0.284	0.104
MADD	DNAJA1	0.281	0.076
TUBA4A	TBCD	0.263	0.312
MADD	ARL2	0.255	0.114
CDC42EP1	TBCD	0.247	0.12
TUBB6	TBCD	0.243	0.252
TUBA1A	TBCD	0.226
PLD2	FAS	0.204	0.138
MADD	RPS27	0.201	0.138
EML6	TBCD	0.195
TCP11L1	EML6	0.182
EML6	FAS	0.176
CAPS	TBCD	0.169	0.118
ARL2	TUBA1A	0.167
EML6	TTC5	0.157
CDC42EP1	CAD	0.156	0.164
DNAJA1	TTC5	0.154	0.128
TUBB8	FAS	0.144	0.19
CAPS	TTC5	0.137	0.072
PLD2	RPS27	0.131	0.154
EML6	TUBB	0.129
TCP11L1	CAPS	0.127	0.1
RPS27	TTC5	0.127	0.21
TUBA1B	TUBB2B	0.12
PLD2	TUBB6	0.116	0.264
TUBA1A	FAS	0.113
TUBB6	CAD	0.102	0.272
ARL2	RPS27	0.089	0.144	structurally_consistent (Q3ZCM7)
DNAJA1	FAS	0.084	0.12
RPS27	FAS	0.083	0.202
EML6	TUBB4A	0.079
ARL2	DNAJA1	0.079	0.094
TUBB2A	EML6	0.075
CAPS	FAS	0.066	0.048	structurally_consistent (Q13885)
TUBA4A	FAS	0.06	0.21
EML6	TUBA1A	0.059
PLD2	CDC42EP1	0.054	0.184
PLD2	CAPS	0.053	0.132
CDC42EP1	CAPS	0.053	0.06
EML6	TUBA4A	0.053
TCP11L1	RPS27	0.052	0.078	structurally_consistent (P68366)
DNAJA1	TBCD	0.051	0.226
CAD	TBCD	0.05	0.418
CDC42EP1	EML6	0.049
CAD	TTC5	0.044	0.1
DNAJA1	EML6	0.031
TUBA1B	TTC5	0.029
TUBA1B	FAS	0.027
PLD2	EML6	0.027
EML6	TUBA1B	0.026
MADD	CAPS	0.023	0.066
ARL2	TUBA4A	0.02	0.0662641509434
TCP11L1	PLD2	0.02	0.094
DNAJA1	CAPS	0.019	0.14
ARL2	CAD	0.016	0.07
CDC42EP1	FAS	0.015	0.174
TCP11L1	TUBA1B	0.015
RPS27	CAPS	0.013	0.148
RPS27	EML6	0.011
CAD	FAS	0.01	0.086
TUBA1B	CAPS	0.009
MADD	EML6	0.008
MADD	TUBA1B	0.008
EML6	CAD	0.007
CAPS	CAD	0.005	0.1
ARL2	TUBA1B	0.001

Related Complexes

Genename	Complexes
TUBB8	huMAP3_01878.1 huMAP3_06977.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12871.1
DNAJA1	huMAP3_01335.1 huMAP3_02724.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10363.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
CDC42EP1	huMAP3_01878.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_08981.1 huMAP3_09233.1 huMAP3_09670.1 huMAP3_09835.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11719.1
TUBB	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
CAD	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10103.1 huMAP3_10475.1 huMAP3_10665.1
EML6	huMAP3_02722.1 huMAP3_08179.1 huMAP3_08402.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14043.1 huMAP3_14311.1 huMAP3_14884.1
RPS27	huMAP3_01409.1 huMAP3_01838.1 huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08023.1 huMAP3_08179.1 huMAP3_08373.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11115.1 huMAP3_12301.1 huMAP3_12727.1
PLD2	huMAP3_01335.1 huMAP3_01541.1 huMAP3_03106.1 huMAP3_03228.1 huMAP3_04629.1 huMAP3_05710.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_08225.1 huMAP3_08361.1 huMAP3_09233.1 huMAP3_10018.1 huMAP3_10363.1 huMAP3_10475.1
TUBB2B	huMAP3_06977.1 huMAP3_08179.1 huMAP3_08402.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TTC5	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1 huMAP3_14884.1
TUBA1A	huMAP3_02724.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11156.1
TUBB4A	huMAP3_05787.1 huMAP3_06500.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA4B	huMAP3_03106.1 huMAP3_04859.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA1B	huMAP3_02724.1 huMAP3_03810.1 huMAP3_06559.1 huMAP3_07544.1 huMAP3_07864.1 huMAP3_07938.1 huMAP3_08094.1 huMAP3_08179.1 huMAP3_09191.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10656.1 huMAP3_10665.1 huMAP3_11156.1 huMAP3_14584.1
TUBB6	huMAP3_03106.1 huMAP3_04859.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
MADD	huMAP3_00118.1 huMAP3_00962.1 huMAP3_05951.1 huMAP3_07544.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_10475.1 huMAP3_11346.1
TUBB2A	huMAP3_00118.1 huMAP3_05787.1 huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
TUBB3	huMAP3_02722.1 huMAP3_06977.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1
TUBA4A	huMAP3_05787.1 huMAP3_07625.1 huMAP3_08095.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09258.1 huMAP3_09618.1 huMAP3_10475.1 huMAP3_10665.1
TBCD	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_14311.1
CAPS	huMAP3_03106.1 huMAP3_03532.1 huMAP3_04859.1 huMAP3_06197.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_11669.1 huMAP3_12525.1 huMAP3_13292.1 huMAP3_14468.1 huMAP3_14491.1 huMAP3_14682.1
ARL2	huMAP3_01239.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10142.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_13133.1 huMAP3_14311.1 huMAP3_14884.1
FAS	huMAP3_06977.1 huMAP3_07544.1 huMAP3_07762.1 huMAP3_07864.1 huMAP3_08179.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10665.1 huMAP3_12841.1 huMAP3_14311.1
TCP11L1	huMAP3_00374.1 huMAP3_05787.1 huMAP3_06064.1 huMAP3_07544.1 huMAP3_07625.1 huMAP3_07762.1 huMAP3_08179.1 huMAP3_08262.1 huMAP3_09233.1 huMAP3_09603.1 huMAP3_09670.1 huMAP3_10475.1 huMAP3_10547.1 huMAP3_10665.1 huMAP3_11283.1 huMAP3_14236.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08179.1

Complex Portal: CPX-20873