hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08184.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTAFR | Platelet-activating factor receptor (PAF-R) (PAFr) | 5 | UniProt NCBI |
| EXOG | Nuclease EXOG, mitochondrial (EC 3.1.30.-) (Endonuclease G-like 1) (Endo G-like 1) | 5 | UniProt NCBI |
| EIF2B2 | Translation initiation factor eIF2B subunit beta (S20I15) (S20III15) (eIF2B GDP-GTP exchange factor subunit beta) | 5 | UniProt NCBI |
| EIF2B5 | Translation initiation factor eIF2B subunit epsilon (eIF2B GDP-GTP exchange factor subunit epsilon) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7291 | 2.05032700758e-05 | 0.666666666667 | EIF2B2 EIF2B5 | EIF2B2-EIF2B3-EIF2B4-EIF2B5 complex |
| CORUM:7292 | 3.41705576683e-05 | 0.666666666667 | EIF2B2 EIF2B5 | EIF2B1-EIF2B2-EIF2B3-EIF2B4-EIF2B5 complex |
| REAC:R-HSA-72731 | 0.000190864539041 | 0.666666666667 | EIF2B2 EIF2B5 | Recycling of eIF2:GDP |
| WP:WP107 | 0.00132925024934 | 0.666666666667 | EIF2B2 EIF2B5 | Translation factors |
| WP:WP5316 | 0.00929774738496 | 0.666666666667 | EIF2B2 EIF2B5 | Primary ovarian insufficiency |
| GO:0005851 | 0.0140440992017 | 0.666666666667 | EIF2B2 EIF2B5 | eukaryotic translation initiation factor 2B complex |
| REAC:R-HSA-72737 | 0.0468187221283 | 0.666666666667 | EIF2B2 EIF2B5 | Cap-dependent Translation Initiation |
| REAC:R-HSA-72613 | 0.0468187221283 | 0.666666666667 | EIF2B2 EIF2B5 | Eukaryotic Translation Initiation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| EIF2B2 | EIF2B5 | 1.0 | 0.882 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 fraction boldt_WMM |
| EXOG | EIF2B2 | 0.998 | 0.028 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| EIF2B2 | PTAFR | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| EXOG | EIF2B5 | 0.969 | 0.044 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| PTAFR | EIF2B5 | 0.959 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes