List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_08198.1

Confidence: High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
LIN7A	Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)	5	UniProt   NCBI
MPP3	MAGUK p55 subfamily member 3 (Discs large homolog 3) (Protein MPP3)	5	UniProt   NCBI
DLG4	Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)	5	UniProt   NCBI
KIF26B	Kinesin-like protein KIF26B	4	UniProt   NCBI
CASK	Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)	5	UniProt   NCBI
PALS2	Protein PALS2 (MAGUK p55 subfamily member 6) (Membrane protein, palmitoylated 6) (Veli-associated MAGUK 1) (VAM-1)	4	UniProt   NCBI
APBA1	Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)	5	UniProt   NCBI
MPP2	MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2)	5	UniProt   NCBI
PXDC1	PX domain-containing protein 1	2	UniProt   NCBI
DLG1	Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)	5	UniProt   NCBI
CRB3	Protein crumbs homolog 3	5	UniProt   NCBI
MPP7	MAGUK p55 subfamily member 7	5	UniProt   NCBI
LIN7B	Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2)	5	UniProt   NCBI
LIN7C	Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)	5	UniProt   NCBI
ARHGEF26	Rho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9609736	8.48936242091e-13	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Assembly and cell surface presentation of NMDA receptors
GO:0005911	1.6704118757e-11	0.733333333333	PALS2 DLG4 LIN7B MPP3 CRB3 CASK MPP7 LIN7A MPP2 LIN7C DLG1	cell-cell junction
GO:0097025	2.70401857917e-11	0.333333333333	LIN7C LIN7B MPP7 LIN7A DLG1	MPP7-DLG1-LIN7 complex
CORUM:3207	3.48706226481e-11	0.266666666667	CASK DLG1 LIN7A APBA1	LIN2-LIN7-SAP97-MINT1 complex
REAC:R-HSA-6794362	7.94084765228e-11	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Protein-protein interactions at synapses
REAC:R-HSA-442755	2.09420232846e-10	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-6794361	1.01636748355e-09	0.4	APBA1 DLG4 LIN7B CASK LIN7A LIN7C	Neurexins and neuroligins
REAC:R-HSA-212676	3.26490415271e-09	0.333333333333	CASK LIN7C LIN7A LIN7B APBA1	Dopamine Neurotransmitter Release Cycle
REAC:R-HSA-112314	2.70610815667e-08	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Neurotransmitter receptors and postsynaptic signal transmission
GO:0097016	3.59167413275e-08	0.266666666667	LIN7B LIN7C LIN7A DLG1	L27 domain binding
GO:0070161	3.8607403626e-08	0.733333333333	PALS2 DLG4 LIN7B MPP3 CRB3 CASK MPP7 LIN7A MPP2 LIN7C DLG1	anchoring junction
CORUM:6263	4.24607948444e-08	0.2	LIN7C DLG1 MPP7	MPP7-DLG1-LIN7C complex
CORUM:617	4.24607948444e-08	0.2	CASK LIN7C APBA1	CASK-LIN7C-APBA1 complex
CORUM:1448	4.24607948444e-08	0.2	CASK LIN7A DLG1	LIN2-LIN7-SAP97 complex
CORUM:6260	4.24607948444e-08	0.2	MPP7 LIN7A DLG1	MPP7-DLG1-LIN7A complex
GO:0045197	5.023768739e-08	0.4	CRB3 DLG4 LIN7B LIN7A LIN7C DLG1	establishment or maintenance of epithelial cell apical/basal polarity
REAC:R-HSA-112310	7.97561636444e-08	0.333333333333	CASK LIN7C LIN7A LIN7B APBA1	Neurotransmitter release cycle
GO:0035088	8.16935769203e-08	0.4	CRB3 DLG4 LIN7B LIN7A LIN7C DLG1	establishment or maintenance of apical/basal cell polarity
GO:0061245	8.16935769203e-08	0.4	CRB3 DLG4 LIN7B LIN7A LIN7C DLG1	establishment or maintenance of bipolar cell polarity
REAC:R-HSA-112315	1.57717633613e-07	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Transmission across Chemical Synapses
GO:0030054	1.03327834243e-06	0.8	PALS2 DLG4 APBA1 MPP3 CRB3 CASK MPP7 LIN7A LIN7B MPP2 LIN7C DLG1	cell junction
GO:0005912	1.26534036643e-06	0.466666666667	DLG1 MPP3 DLG4 LIN7B LIN7A LIN7C MPP7	adherens junction
REAC:R-HSA-112316	2.2880891238e-06	0.466666666667	APBA1 DLG1 LIN7B CASK LIN7A LIN7C DLG4	Neuronal System
GO:0007163	4.13040598709e-06	0.466666666667	CRB3 MPP7 DLG4 LIN7B LIN7A LIN7C DLG1	establishment or maintenance of cell polarity
GO:0098916	2.97166334214e-05	0.533333333333	APBA1 DLG1 LIN7B MPP2 CASK LIN7A LIN7C DLG4	anterograde trans-synaptic signaling
GO:0007268	2.97166334214e-05	0.533333333333	APBA1 DLG1 LIN7B MPP2 CASK LIN7A LIN7C DLG4	chemical synaptic transmission
GO:0099537	3.24925916399e-05	0.533333333333	APBA1 DLG1 LIN7B MPP2 CASK LIN7A LIN7C DLG4	trans-synaptic signaling
CORUM:3208	4.77291996201e-05	0.133333333333	CASK LIN7A	LIN2-LIN7 complex
CORUM:3209	4.77291996201e-05	0.133333333333	CASK DLG1	LIN2-SAP97 complex
CORUM:1089	4.77291996201e-05	0.133333333333	PALS2 LIN7A	VAM1-VELI1 complex
GO:0099536	5.10888119081e-05	0.533333333333	APBA1 DLG1 LIN7B MPP2 CASK LIN7A LIN7C DLG4	synaptic signaling
GO:0098590	5.39974820762e-05	0.6	DLG1 LIN7B MPP2 CRB3 CASK LIN7A MPP3 LIN7C DLG4	plasma membrane region
GO:0016323	0.000135764537456	0.4	DLG1 LIN7B CASK LIN7A LIN7C DLG4	basolateral plasma membrane
WP:WP5417	0.00016131142096	0.266666666667	CASK DLG1 LIN7A DLG4	Cell lineage map for neuronal differentiation
GO:0009925	0.000298661678699	0.4	DLG1 LIN7B CASK LIN7A LIN7C DLG4	basal plasma membrane
GO:0045178	0.000389512035466	0.4	DLG1 LIN7B CASK LIN7A LIN7C DLG4	basal part of cell
GO:0045202	0.000773779827535	0.533333333333	APBA1 DLG1 LIN7B MPP2 CASK LIN7A LIN7C DLG4	synapse
GO:1903361	0.00152694380207	0.2	LIN7B LIN7A LIN7C	protein localization to basolateral plasma membrane
GO:0045199	0.00244160521127	0.2	LIN7B LIN7A LIN7C	maintenance of epithelial cell apical/basal polarity
GO:0035090	0.00244160521127	0.2	LIN7B LIN7A LIN7C	maintenance of apical/basal cell polarity
GO:0019904	0.00248642746352	0.466666666667	CRB3 MPP7 DLG4 LIN7B LIN7A LIN7C DLG1	protein domain specific binding
REAC:R-HSA-451308	0.00293854252908	0.133333333333	DLG4 DLG1	Activation of Ca-permeable Kainate Receptor
REAC:R-HSA-451306	0.00293854252908	0.133333333333	DLG4 DLG1	Ionotropic activity of kainate receptors
REAC:R-HSA-447038	0.00616362235606	0.133333333333	DLG4 DLG1	NrCAM interactions
GO:0030011	0.0158118674804	0.2	LIN7B LIN7A LIN7C	maintenance of cell polarity
REAC:R-HSA-442982	0.026598363591	0.133333333333	DLG4 DLG1	Ras activation upon Ca2+ influx through NMDA receptor
REAC:R-HSA-9617324	0.0396807363997	0.133333333333	DLG4 DLG1	Negative regulation of NMDA receptor-mediated neuronal transmission
REAC:R-HSA-438066	0.0396807363997	0.133333333333	DLG4 DLG1	Unblocking of NMDA receptors, glutamate binding and activation
REAC:R-HSA-8849932	0.0446143620426	0.133333333333	DLG4 DLG1	Synaptic adhesion-like molecules
REAC:R-HSA-9620244	0.0446143620426	0.133333333333	DLG4 DLG1	Long-term potentiation
CORUM:6321	0.0498224659463	0.0666666666667	DLG4	DLG4-DLGAP1-SHANK3 complex
CORUM:1909	0.0498224659463	0.0666666666667	DLG4	APC-DLG4 complex
CORUM:4869	0.0498224659463	0.0666666666667	DLG1	beta(1)-AR receptosome (ADRB1-SAP97-AKAP79-PRKAR2A)



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
LIN7C	PALS2	1.0	0.086
LIN7A	MPP2	1.0
LIN7B	MPP2	1.0
DLG1	LIN7C	1.0
LIN7C	MPP2	1.0
PALS2	MPP2	1.0
MPP7	LIN7C	0.999	0.078
DLG1	MPP2	0.999
APBA1	CASK	0.999
CASK	LIN7C	0.999
APBA1	DLG1	0.999
APBA1	LIN7C	0.999	0.098
MPP3	LIN7C	0.998
PXDC1	LIN7C	0.998	0.17
DLG1	LIN7B	0.997
CASK	LIN7B	0.997
APBA1	LIN7B	0.997
CASK	DLG1	0.997
ARHGEF26	LIN7C	0.996	0.09
LIN7B	LIN7C	0.996
DLG1	MPP7	0.996
CASK	MPP7	0.995
MPP7	LIN7B	0.995
LIN7B	PALS2	0.995
PXDC1	LIN7B	0.994
KIF26B	LIN7C	0.994	0.124
APBA1	PXDC1	0.993	0.13
MPP3	LIN7B	0.991
CASK	PXDC1	0.991
LIN7A	PALS2	0.987	0.054
CASK	PALS2	0.984
KIF26B	MPP7	0.984	0.102
DLG4	LIN7C	0.982	0.178
APBA1	DLG4	0.981	0.106
CRB3	LIN7C	0.978
LIN7A	APBA1	0.974	0.152
MPP3	PXDC1	0.967
APBA1	MPP3	0.967
KIF26B	DLG1	0.967
MPP7	PALS2	0.966	0.132
MPP3	CASK	0.96
MPP3	MPP7	0.958
MPP3	DLG1	0.958
MPP3	MPP2	0.958
ARHGEF26	APBA1	0.954	0.242
MPP3	PALS2	0.951
PXDC1	DLG1	0.95
KIF26B	LIN7B	0.937
ARHGEF26	DLG1	0.93
MPP7	MPP2	0.917
CASK	MPP2	0.914
ARHGEF26	MPP3	0.908
DLG4	CRB3	0.902
DLG4	MPP3	0.902
CRB3	MPP3	0.902
APBA1	MPP7	0.898	0.088
APBA1	MPP2	0.895
APBA1	PALS2	0.893	0.052
PXDC1	MPP7	0.888	0.082
PXDC1	MPP2	0.885
KIF26B	CASK	0.88
PXDC1	PALS2	0.879	0.1
ARHGEF26	LIN7B	0.873
LIN7A	LIN7C	0.853	0.142
DLG1	PALS2	0.85
ARHGEF26	PXDC1	0.849	0.176
ARHGEF26	CASK	0.849
ARHGEF26	MPP7	0.776	0.25
ARHGEF26	PALS2	0.742	0.124
ARHGEF26	MPP2	0.723
CRB3	PXDC1	0.717
APBA1	CRB3	0.717
ARHGEF26	CRB3	0.696
KIF26B	PXDC1	0.691	0.064
ARHGEF26	DLG4	0.642	0.184
DLG4	LIN7B	0.64
DLG4	DLG1	0.633
DLG4	CASK	0.633
LIN7A	LIN7B	0.63
DLG4	PXDC1	0.616	0.096
LIN7A	DLG1	0.606
MPP3	KIF26B	0.583
APBA1	KIF26B	0.566	0.068
ARHGEF26	KIF26B	0.466	0.136
CRB3	CASK	0.459
DLG4	MPP2	0.45
CRB3	MPP2	0.45
CRB3	MPP7	0.45
DLG4	MPP7	0.45	0.096
LIN7A	CASK	0.449
CRB3	DLG1	0.437
DLG4	PALS2	0.388	0.078
CRB3	PALS2	0.388
KIF26B	MPP2	0.357
LIN7A	DLG4	0.356	0.104
KIF26B	PALS2	0.353	0.074
CRB3	LIN7B	0.352
LIN7A	PXDC1	0.332	0.05
LIN7A	CRB3	0.225
CRB3	KIF26B	0.214
DLG4	KIF26B	0.214	0.186
LIN7A	MPP7	0.079	0.054
ARHGEF26	LIN7A	0.022	0.176





Related Complexes

Genename	Complexes
LIN7A	huMAP3_00243.1 huMAP3_05314.1 huMAP3_06839.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_10716.1 huMAP3_11195.1 huMAP3_14575.1
MPP3	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_11270.1 huMAP3_14575.1
DLG4	huMAP3_00243.1 huMAP3_05036.1 huMAP3_05627.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_11270.1 huMAP3_14575.1
KIF26B	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
CASK	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
PALS2	huMAP3_05314.1 huMAP3_06839.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_10716.1 huMAP3_11195.1 huMAP3_14575.1
APBA1	huMAP3_00243.1 huMAP3_05627.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
MPP2	huMAP3_05314.1 huMAP3_06839.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_10716.1 huMAP3_11195.1 huMAP3_14575.1
PXDC1	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
DLG1	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
CRB3	huMAP3_03320.1 huMAP3_04256.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_10760.1 huMAP3_11195.1 huMAP3_11270.1 huMAP3_14575.1
MPP7	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
LIN7B	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
LIN7C	huMAP3_05036.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
ARHGEF26	huMAP3_00174.1 huMAP3_08198.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1