hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08214.1
Complex Portal: CPX-21300
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ARL6IP1 | ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum) | 5 | UniProt NCBI |
| RTN2 | Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI) | 5 | UniProt NCBI |
| RTN4 | Reticulon-4 (Foocen) (Neurite outgrowth inhibitor) (Nogo protein) (Neuroendocrine-specific protein) (NSP) (Neuroendocrine-specific protein C homolog) (RTN-x) (Reticulon-5) | 5 | UniProt NCBI |
| SVOPL | Putative transporter SVOPL (SV2-related protein-like) (SVOP-like protein) | 3 | UniProt NCBI |
| CYB5R3 | NADH-cytochrome b5 reductase 3 (B5R) (Cytochrome b5 reductase) (EC 1.6.2.2) (Diaphorase-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1990809 | 0.0280843539964 | 0.4 | ARL6IP1 RTN4 | endoplasmic reticulum tubular network membrane organization |
| HP:0007054 | 0.0402186552091 | 0.4 | ARL6IP1 RTN2 | Proximal hyperreflexia |
| GO:0071787 | 0.0468008499735 | 0.4 | ARL6IP1 RTN4 | endoplasmic reticulum tubular network formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RTN4 | ARL6IP1 | 0.999 | 0.206 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RTN4 | RTN2 | 0.999 | 0.114 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RTN4 | CYB5R3 | 0.991 | 0.244 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| SVOPL | RTN4 | 0.965 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ARL6IP1 | RTN2 | 0.958 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only | |
| ARL6IP1 | CYB5R3 | 0.81 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only | |
| CYB5R3 | RTN2 | 0.588 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| SVOPL | RTN2 | 0.462 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes