hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08219.1
Complex Portal: CPX-25149
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| EDC4 | Enhancer of mRNA-decapping protein 4 (Autoantigen Ge-1) (Autoantigen RCD-8) (Human enhancer of decapping large subunit) (Hedls) | 5 | UniProt NCBI |
| DCP2 | m7GpppN-mRNA hydrolase (EC 3.6.1.62) (Nucleoside diphosphate-linked moiety X motif 20) (Nudix motif 20) (mRNA-decapping enzyme 2) (hDpc) | 5 | UniProt NCBI |
| MARF1 | Meiosis regulator and mRNA stability factor 1 (Limkain-b1) (Meiosis arrest female protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:559 | 3.41705576683e-05 | 0.666666666667 | DCP2 EDC4 | Decapping complex |
| REAC:R-HSA-430039 | 0.000715513386354 | 0.666666666667 | DCP2 EDC4 | mRNA decay by 5' to 3' exoribonuclease |
| KEGG:03018 | 0.0019996401701 | 0.666666666667 | DCP2 EDC4 | RNA degradation |
| REAC:R-HSA-429914 | 0.0101009261622 | 0.666666666667 | DCP2 EDC4 | Deadenylation-dependent mRNA decay |
| CORUM:1296 | 0.0499402709677 | 0.333333333333 | DCP2 | DCP1A-DCP2 Decapping complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| EDC4 | DCP2 | 0.999 | 0.282 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 treiber_WMM | |
| MARF1 | DCP2 | 0.985 | 0.222 | hein_WMM youn () youn_WMM WMM_only | |
| MARF1 | EDC4 | 0.978 | 0.152 | hein_WMM youn () youn_WMM hein () |
Related Complexes