hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08224.1
Complex Portal: CPX-13907
Confidence: High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C4B | Complement C4-B (Basic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3) [Cleaved into: Complement C4 beta chain; Complement C4-B alpha chain; C4a anaphylatoxin; C4b-B; C4d-B; Complement C4 gamma chain] | 5 | UniProt   NCBI |
| OR6C70 | Olfactory receptor 6C70 | 3 | UniProt   NCBI |
| GC | Vitamin D-binding protein (DBP) (VDB) (Gc protein-derived macrophage activating factor) (Gc-MAF) (GcMAF) (Gc-globulin) (Group-specific component) (Gc) (Vitamin D-binding protein-macrophage activating factor) (DBP-maf) | 5 | UniProt   NCBI |
| SERPINA3 | Alpha-1-antichymotrypsin (ACT) (Cell growth-inhibiting gene 24/25 protein) (Serpin A3) [Cleaved into: Alpha-1-antichymotrypsin His-Pro-less] | 5 | UniProt   NCBI |
| TF | Serotransferrin (Transferrin) (Beta-1 metal-binding globulin) (Siderophilin) | 5 | UniProt   NCBI |
| HPR | Haptoglobin-related protein | 5 | UniProt   NCBI |
| PGLYRP1 | Peptidoglycan recognition protein 1 (Peptidoglycan recognition protein short) (PGRP-S) | 5 | UniProt   NCBI |
| APOL1 | Apolipoprotein L1 (Apolipoprotein L) (Apo-L) (ApoL) (Apolipoprotein L-I) (ApoL-I) | 5 | UniProt   NCBI |
| PTPRC | Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) | 5 | UniProt   NCBI |
| C3 | Complement C3 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1) [Cleaved into: Complement C3 beta chain; C3-beta-c (C3bc); Complement C3 alpha chain; C3a anaphylatoxin; Acylation stimulating protein (ASP) (C3adesArg); Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3dg fragment; Complement C3g fragment; Complement C3d fragment; Complement C3f fragment; Complement C3c alpha' chain fragment 2] | 5 | UniProt   NCBI |
| FGA | Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain] | 5 | UniProt   NCBI |
| KLK10 | Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1) | 5 | UniProt   NCBI |
| PADI2 | Protein-arginine deiminase type-2 (EC 3.5.3.15) (PAD-H19) (Peptidylarginine deiminase II) (Protein-arginine deiminase type II) | 5 | UniProt   NCBI |
| FGG | Fibrinogen gamma chain | 5 | UniProt   NCBI |
| SERPIND1 | Heparin cofactor 2 (Heparin cofactor II) (HC-II) (Protease inhibitor leuserpin-2) (HLS2) (Serpin D1) | 5 | UniProt   NCBI |
| APOC1 | Apolipoprotein C-I (Apo-CI) (ApoC-I) (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I] | 5 | UniProt   NCBI |
| C5 | Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain] | 5 | UniProt   NCBI |
| DYSF | Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1) | 5 | UniProt   NCBI |
| NCF2 | Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox) | 5 | UniProt   NCBI |
| HP | Haptoglobin (Zonulin) [Cleaved into: Haptoglobin alpha chain; Haptoglobin beta chain] | 5 | UniProt   NCBI |
| APOA1 | Apolipoprotein A-I (Apo-AI) (ApoA-I) (Apolipoprotein A1) [Cleaved into: Proapolipoprotein A-I (ProapoA-I); Truncated apolipoprotein A-I (Apolipoprotein A-I(1-242))] | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   GO:0072562 | 1.45620108552e-14 | 0.52380952381 | HPR C4B HP APOL1 APOA1 FGA FGG C3 GC TF SERPINA3 | blood microparticle |
|   CORUM:6819 | 1.09361872632e-10 | 0.190476190476 | HPR APOA1 C3 APOL1 | APOL1 complex A (APOL1, APOA1, HPR, C3) |
|   REAC:R-HSA-8957275 | 7.21561555286e-09 | 0.333333333333 | C3 APOL1 FGA SERPIND1 FGG TF APOA1 | Post-translational protein phosphorylation |
|   REAC:R-HSA-381426 | 1.95515117198e-08 | 0.333333333333 | C3 APOL1 FGA SERPIND1 FGG TF APOA1 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
|   KEGG:04610 | 3.18896886911e-08 | 0.285714285714 | C4B FGA C5 FGG SERPIND1 C3 | Complement and coagulation cascades |
|   GO:0005576 | 1.61596402575e-07 | 0.904761904762 | HPR C4B PTPRC APOL1 APOC1 FGG FGA KLK10 PADI2 HP PGLYRP1 DYSF SERPIND1 C3 GC C5 TF APOA1 SERPINA3 | extracellular region |
|   WP:WP5115 | 3.30276938765e-07 | 0.333333333333 | APOA1 HP APOL1 FGA FGG APOC1 TF | Network map of SARS CoV 2 signaling pathway |
|   CORUM:6820 | 3.54782066137e-07 | 0.142857142857 | HPR APOA1 APOL1 | APOL1 complex B (APOL1, APOA1, HPR, FN1, IGHM) |
|   REAC:R-HSA-2168880 | 4.95990512365e-07 | 0.190476190476 | HPR HP APOA1 APOL1 | Scavenging of heme from plasma |
|   GO:0005615 | 8.07077828216e-07 | 0.857142857143 | HPR C4B PTPRC APOL1 APOC1 FGG FGA SERPIND1 PADI2 HP PGLYRP1 DYSF C3 GC C5 TF APOA1 SERPINA3 | extracellular space |
|   GO:0070062 | 1.90010880284e-06 | 0.761904761905 | HPR C4B PTPRC APOA1 FGG FGA SERPIND1 PADI2 HP PGLYRP1 DYSF C3 GC C5 TF SERPINA3 | extracellular exosome |
|   GO:1903561 | 2.19062591172e-06 | 0.761904761905 | HPR C4B PTPRC APOA1 FGG FGA SERPIND1 PADI2 HP PGLYRP1 DYSF C3 GC C5 TF SERPINA3 | extracellular vesicle |
|   GO:0065010 | 2.20894162801e-06 | 0.761904761905 | HPR C4B PTPRC APOA1 FGG FGA SERPIND1 PADI2 HP PGLYRP1 DYSF C3 GC C5 TF SERPINA3 | extracellular membrane-bounded organelle |
|   GO:0043230 | 2.20894162801e-06 | 0.761904761905 | HPR C4B PTPRC APOA1 FGG FGA SERPIND1 PADI2 HP PGLYRP1 DYSF C3 GC C5 TF SERPINA3 | extracellular organelle |
|   REAC:R-HSA-168249 | 2.52438923052e-06 | 0.52380952381 | PTPRC C3 FGG NCF2 FGA C5 PADI2 PGLYRP1 SERPINA3 HP C4B | Innate Immune System |
|   GO:0099503 | 2.79957227824e-06 | 0.571428571429 | PTPRC C3 FGG APOA1 DYSF FGA KLK10 PADI2 PGLYRP1 HP TF SERPINA3 | secretory vesicle |
|   GO:0034774 | 4.87412236672e-06 | 0.428571428571 | C3 FGG APOA1 FGA PADI2 PGLYRP1 HP TF SERPINA3 | secretory granule lumen |
|   GO:0060205 | 5.18297972811e-06 | 0.428571428571 | C3 FGG APOA1 FGA PADI2 PGLYRP1 HP TF SERPINA3 | cytoplasmic vesicle lumen |
|   GO:0031983 | 5.34379341988e-06 | 0.428571428571 | C3 FGG APOA1 FGA PADI2 PGLYRP1 HP TF SERPINA3 | vesicle lumen |
|   WP:WP2806 | 8.32835451352e-06 | 0.238095238095 | FGG C5 C3 APOA1 FGA | Complement system |
|   GO:0031982 | 1.23459411849e-05 | 0.857142857143 | HPR C4B PTPRC NCF2 APOA1 FGG FGA KLK10 PADI2 HP PGLYRP1 DYSF SERPIND1 C3 GC C5 TF SERPINA3 | vesicle |
|   GO:0030141 | 1.4546315152e-05 | 0.52380952381 | PTPRC C3 FGG APOA1 FGA KLK10 PADI2 PGLYRP1 HP TF SERPINA3 | secretory granule |
|   REAC:R-HSA-174577 | 2.85761248074e-05 | 0.142857142857 | C5 C4B C3 | Activation of C3 and C5 |
|   GO:0060627 | 3.42131603333e-05 | 0.428571428571 | PTPRC C3 DYSF APOA1 FGA FGG APOC1 TF C4B | regulation of vesicle-mediated transport |
|   KEGG:05150 | 4.4263825273e-05 | 0.190476190476 | FGG C5 C4B C3 | Staphylococcus aureus infection |
|   REAC:R-HSA-2173782 | 5.13526282739e-05 | 0.190476190476 | HPR HP APOA1 APOL1 | Binding and Uptake of Ligands by Scavenger Receptors |
|   REAC:R-HSA-114608 | 0.000103503935537 | 0.238095238095 | FGG FGA APOA1 SERPINA3 TF | Platelet degranulation |
|   KEGG:04613 | 0.00010792977244 | 0.238095238095 | NCF2 FGG C5 C3 FGA | Neutrophil extracellular trap formation |
|   WP:WP176 | 0.000125841279376 | 0.190476190476 | FGG APOA1 SERPINA3 FGA | Folate metabolism |
|   REAC:R-HSA-76005 | 0.000130592694123 | 0.238095238095 | FGG FGA APOA1 SERPINA3 TF | Response to elevated platelet cytosolic Ca2+ |
|   CORUM:6417 | 0.000204660259961 | 0.0952380952381 | FGG FGA | Fibrinogen complex |
|   WP:WP545 | 0.000210843558531 | 0.142857142857 | C5 C4B C3 | Complement activation |
|   GO:0034364 | 0.000212770750591 | 0.190476190476 | HPR APOA1 APOC1 APOL1 | high-density lipoprotein particle |
|   WP:WP15 | 0.000296869445973 | 0.190476190476 | FGG APOA1 SERPINA3 FGA | Selenium micronutrient network |
|   GO:0030100 | 0.000323698172005 | 0.333333333333 | PTPRC C3 DYSF APOA1 APOC1 TF C4B | regulation of endocytosis |
|   GO:1990777 | 0.000475649605248 | 0.190476190476 | HPR APOA1 APOC1 APOL1 | lipoprotein particle |
|   GO:0034358 | 0.000475649605248 | 0.190476190476 | HPR APOA1 APOC1 APOL1 | plasma lipoprotein particle |
|   KEGG:05171 | 0.000479314288262 | 0.238095238095 | FGG FGA C5 C4B C3 | Coronavirus disease - COVID-19 |
|   REAC:R-HSA-140875 | 0.000550085437963 | 0.142857142857 | FGG FGA SERPIND1 | Common Pathway of Fibrin Clot Formation |
|   KEGG:05143 | 0.000658001348084 | 0.142857142857 | HPR APOA1 APOL1 | African trypanosomiasis |
|   GO:0032994 | 0.000927718555523 | 0.190476190476 | HPR APOA1 APOC1 APOL1 | protein-lipid complex |
|   HP:0000988 | 0.000991989762003 | 0.238095238095 | NCF2 PTPRC APOA1 C4B FGA | Skin rash |
|   GO:0005788 | 0.00171867491572 | 0.333333333333 | C3 APOL1 FGA SERPIND1 FGG TF APOA1 | endoplasmic reticulum lumen |
|   REAC:R-HSA-168256 | 0.00175907007428 | 0.52380952381 | PTPRC C3 FGG NCF2 FGA C5 PADI2 PGLYRP1 SERPINA3 HP C4B | Immune System |
|   GO:0031410 | 0.00208185194651 | 0.619047619048 | PTPRC C3 FGG NCF2 APOA1 DYSF FGA KLK10 PADI2 PGLYRP1 HP TF SERPINA3 | cytoplasmic vesicle |
|   GO:0097708 | 0.00212792542024 | 0.619047619048 | PTPRC C3 FGG NCF2 APOA1 DYSF FGA KLK10 PADI2 PGLYRP1 HP TF SERPINA3 | intracellular vesicle |
|   GO:0050764 | 0.00224598616417 | 0.238095238095 | PTPRC APOA1 DYSF C4B C3 | regulation of phagocytosis |
|   REAC:R-HSA-140877 | 0.00358948171295 | 0.142857142857 | FGG FGA SERPIND1 | Formation of Fibrin Clot (Clotting Cascade) |
|   WP:WP4927 | 0.00361111981408 | 0.0952380952381 | FGG FGA | COVID 19 thrombosis and anticoagulation |
|   REAC:R-HSA-76002 | 0.003702442397 | 0.238095238095 | FGG FGA APOA1 SERPINA3 TF | Platelet activation, signaling and aggregation |
|   KEGG:05133 | 0.00463728868438 | 0.142857142857 | C5 C4B C3 | Pertussis |
|   WP:WP558 | 0.00489021544052 | 0.142857142857 | SERPIND1 C4B C3 | Complement and coagulation cascades |
|   HP:0400008 | 0.00701692319865 | 0.0952380952381 | FGG FGA | Menometrorrhagia |
|   HP:0034287 | 0.00701692319865 | 0.0952380952381 | FGG FGA | Afibrinogenemia |
|   REAC:R-HSA-6798695 | 0.00738491897702 | 0.285714285714 | PTPRC C3 PADI2 HP PGLYRP1 SERPINA3 | Neutrophil degranulation |
|   REAC:R-HSA-977606 | 0.00843423915171 | 0.142857142857 | C5 C4B C3 | Regulation of Complement cascade |
|   GO:0002376 | 0.00862170043979 | 0.571428571429 | PTPRC C3 DYSF APOL1 APOA1 FGA C5 PADI2 PGLYRP1 NCF2 TF C4B | immune system process |
|   WP:WP5104 | 0.00864417645563 | 0.0952380952381 | C3 C5 | Acquired partial lipodystrophy Barraquer Simons syndrome |
|   HP:0000093 | 0.00902977913775 | 0.238095238095 | APOL1 FGA APOA1 C4B C3 | Proteinuria |
|   HP:0020129 | 0.0134474191838 | 0.238095238095 | APOL1 FGA APOA1 C4B C3 | Abnormal urine protein level |
|   REAC:R-HSA-166658 | 0.0135964405716 | 0.142857142857 | C5 C4B C3 | Complement cascade |
|   WP:WP2328 | 0.0141829488343 | 0.142857142857 | C5 C4B C3 | Allograft rejection |
|   HP:0011123 | 0.0174261373181 | 0.285714285714 | PTPRC C4B NCF2 C5 FGA APOA1 | Inflammatory abnormality of the skin |
|   GO:0045807 | 0.0177440983181 | 0.238095238095 | C3 PTPRC APOA1 C4B TF | positive regulation of endocytosis |
|   WP:WP4493 | 0.0186642269482 | 0.0952380952381 | C3 C5 | Cells and molecules involved in local acute inflammatory response |
|   HP:0100763 | 0.0202886630797 | 0.333333333333 | PTPRC C4B NCF2 APOA1 FGA FGG C3 | Abnormality of the lymphatic system |
|   GO:0006952 | 0.0219421824584 | 0.47619047619 | PTPRC SERPINA3 APOL1 FGA C5 HP PGLYRP1 NCF2 TF APOA1 | defense response |
|   REAC:R-HSA-109582 | 0.0229054025689 | 0.285714285714 | APOA1 FGA TF FGG SERPIND1 SERPINA3 | Hemostasis |
|   HP:0100310 | 0.023349216204 | 0.0952380952381 | FGG FGA | Epidural hemorrhage |
|   HP:0012223 | 0.023349216204 | 0.0952380952381 | FGG FGA | Splenic rupture |
|   GO:0006955 | 0.0251465518969 | 0.47619047619 | PTPRC C3 DYSF APOL1 FGA APOA1 PGLYRP1 NCF2 TF C4B | immune response |
|   KEGG:05322 | 0.0278333210506 | 0.142857142857 | C5 C4B C3 | Systemic lupus erythematosus |
|   WP:WP5090 | 0.032945799547 | 0.142857142857 | C5 C4B C3 | Complement system in neuronal development and plasticity |
|   REAC:R-HSA-354194 | 0.0343954281992 | 0.0952380952381 | FGG FGA | GRB2:SOS provides linkage to MAPK signaling for Integrins |
|   HP:0003216 | 0.0349934705793 | 0.0952380952381 | FGA APOA1 | Generalized amyloid deposition |
|   HP:0011122 | 0.0359164928597 | 0.285714285714 | PTPRC C4B NCF2 C5 FGA APOA1 | Abnormality of skin physiology |
|   HP:0004431 | 0.0362002638118 | 0.142857142857 | C5 C4B C3 | Complement deficiency |
|   GO:0034361 | 0.0362257557392 | 0.142857142857 | APOL1 APOC1 APOA1 | very-low-density lipoprotein particle |
|   GO:0034385 | 0.0362257557392 | 0.142857142857 | APOL1 APOC1 APOA1 | triglyceride-rich plasma lipoprotein particle |
|   WP:WP272 | 0.0364523199885 | 0.0952380952381 | FGG FGA | Blood clotting cascade |
|   GO:0050766 | 0.0407695423619 | 0.190476190476 | PTPRC APOA1 C4B C3 | positive regulation of phagocytosis |
|   REAC:R-HSA-372708 | 0.0412387552064 | 0.0952380952381 | FGG FGA | p130Cas linkage to MAPK signaling for integrins |
|   KEGG:04936 | 0.0416601991328 | 0.142857142857 | C5 C4B C3 | Alcoholic liver disease |
|   HP:0005339 | 0.0444047297639 | 0.142857142857 | C5 C4B C3 | Abnormality of complement system |
|   HP:0011884 | 0.0489484028541 | 0.0952380952381 | FGG FGA | Abnormal umbilical stump bleeding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
|  C3 |  APOA1 | 0.993 | 0.49           |          |
|  FGA |  APOA1 | 0.991 | 0.366           |          |
|  FGG |  APOA1 | 0.99 | 0.418           |          |
|  HP |  HPR | 0.989 |            |
structurally_consistent (dimer)        
|
|  APOC1 |  KLK10 | 0.989 |            |          |
|  APOL1 |  KLK10 | 0.989 |            |          |
|  KLK10 |  FGA | 0.986 |            |          |
|  FGG |  C3 | 0.986 | 0.512           |          |
|  HP |  C3 | 0.985 | 0.44           |          |
|  KLK10 |  HP | 0.985 |            |          |
|  TF |  APOA1 | 0.985 | 0.37           |          |
|  DYSF |  KLK10 | 0.984 |            |          |
|  HP |  APOA1 | 0.983 | 0.458           |          |
|  HP |  SERPINA3 | 0.982 | 0.342           |          |
|  FGA |  TF | 0.982 | 0.306           |          |
|  KLK10 |  C3 | 0.981 |            |          |
|  SERPINA3 |  APOA1 | 0.981 | 0.388           |          |
|  KLK10 |  APOA1 | 0.98 |            |          |
|  KLK10 |  HPR | 0.98 |            |          |
|  C3 |  TF | 0.979 | 0.49           |          |
|  FGG |  FGA | 0.979 | 0.364           |
structurally_consistent (dimer)        
|
|  KLK10 |  FGG | 0.978 |            |          |
|  PADI2 |  KLK10 | 0.977 |            |          |
|  FGG |  TF | 0.976 | 0.388           |          |
|  PTPRC |  KLK10 | 0.975 |            |          |
|  KLK10 |  TF | 0.972 |            |          |
|  C3 |  FGA | 0.972 | 0.428           |          |
|  C3 |  SERPINA3 | 0.971 | 0.366           |          |
|  PGLYRP1 |  KLK10 | 0.97 |            |          |
|  OR6C70 |  KLK10 | 0.968 |            |          |
|  HP |  TF | 0.968 | 0.368           |          |
|  HP |  FGA | 0.966 | 0.338           |          |
|  KLK10 |  GC | 0.963 |            |          |
|  NCF2 |  KLK10 | 0.962 |            |          |
|  KLK10 |  SERPIND1 | 0.962 |            |          |
|  C5 |  KLK10 | 0.96 |            |          |
|  SERPINA3 |  TF | 0.953 | 0.364           |          |
|  HP |  FGG | 0.944 | 0.37           |          |
|  FGA |  SERPINA3 | 0.93 | 0.3           |          |
|  C5 |  PGLYRP1 | 0.904 |            |          |
|  PGLYRP1 |  HPR | 0.904 |            |          |
|  DYSF |  APOC1 | 0.902 |            |          |
|  DYSF |  NCF2 | 0.902 | 0.07           |          |
|  PTPRC |  NCF2 | 0.902 | 0.1606           |          |
|  NCF2 |  APOC1 | 0.902 |            |          |
|  APOL1 |  NCF2 | 0.902 |            |          |
|  PGLYRP1 |  PTPRC | 0.902 |            |          |
|  PTPRC |  APOC1 | 0.902 |            |          |
|  DYSF |  PTPRC | 0.902 | 0.325010752688           |          |
|  PGLYRP1 |  DYSF | 0.902 |            |          |
|  APOL1 |  DYSF | 0.902 | 0.110115942029           |          |
|  PGLYRP1 |  APOC1 | 0.902 |            |          |
|  APOL1 |  APOC1 | 0.902 |            |          |
|  PGLYRP1 |  APOL1 | 0.902 |            |          |
|  APOL1 |  PTPRC | 0.902 | 0.302           |          |
|  PGLYRP1 |  NCF2 | 0.902 |            |          |
|  PTPRC |  HPR | 0.902 |            |          |
|  C5 |  DYSF | 0.902 | 0.07           |          |
|  PADI2 |  NCF2 | 0.902 | 0.132           |          |
|  APOL1 |  HPR | 0.902 |            |          |
|  PADI2 |  PTPRC | 0.902 | 0.28           |          |
|  APOC1 |  HPR | 0.902 |            |          |
|  PADI2 |  DYSF | 0.902 | 0.096           |          |
|  PGLYRP1 |  PADI2 | 0.902 |            |          |
|  DYSF |  HPR | 0.902 |            |          |
|  C5 |  APOC1 | 0.902 |            |          |
|  C5 |  PTPRC | 0.902 | 0.234           |          |
|  PADI2 |  APOL1 | 0.902 |            |          |
|  PADI2 |  APOC1 | 0.902 |            |          |
|  C5 |  APOL1 | 0.902 | 0.282           |          |
|  C3 |  GC | 0.888 | 0.426           |          |
|  APOA1 |  GC | 0.888 | 0.192           |          |
|  HP |  GC | 0.886 | 0.344           |          |
|  FGG |  SERPINA3 | 0.877 | 0.342           |          |
|  TF |  GC | 0.872 | 0.318           |          |
|  FGA |  GC | 0.867 | 0.306           |          |
|  SERPINA3 |  GC | 0.836 | 0.258           |          |
|  FGG |  GC | 0.806 | 0.258           |          |
|  SERPINA3 |  HPR | 0.797 |            |          |
|  FGA |  HPR | 0.796 |            |          |
|  HPR |  GC | 0.784 |            |          |
|  SERPIND1 |  HPR | 0.783 |            |          |
|  C5 |  NCF2 | 0.768 | 0.086           |          |
|  NCF2 |  HPR | 0.768 |            |          |
|  SERPIND1 |  GC | 0.766 | 0.368           |          |
|  PADI2 |  HPR | 0.722 |            |          |
|  C5 |  PADI2 | 0.714 | 0.058           |          |
|  SERPIND1 |  TF | 0.71 | 0.224           |          |
|  SERPIND1 |  FGA | 0.709 | 0.338           |          |
|  SERPIND1 |  C3 | 0.709 | 0.28           |          |
|  SERPIND1 |  FGG | 0.709 | 0.342           |          |
|  DYSF |  SERPIND1 | 0.698 | 0.13           |          |
|  APOC1 |  SERPIND1 | 0.698 |            |          |
|  PTPRC |  SERPIND1 | 0.698 | 0.27           |          |
|  APOL1 |  SERPIND1 | 0.698 | 0.234           |          |
|  SERPIND1 |  APOA1 | 0.686 | 0.35           |          |
|  FGG |  HPR | 0.667 |            |          |
|  PADI2 |  SERPIND1 | 0.638 | 0.092           |          |
|  C5 |  HPR | 0.633 |            |          |
|  PGLYRP1 |  SERPIND1 | 0.626 |            |          |
|  C3 |  HPR | 0.625 |            |          |
|  HPR |  APOA1 | 0.616 |            |          |
|  TF |  HPR | 0.602 |            |          |
|  HP |  SERPIND1 | 0.573 | 0.292           |          |
|  KLK10 |  SERPINA3 | 0.559 |            |
structurally_consistent (O15547)        
|
|  SERPIND1 |  SERPINA3 | 0.54 | 0.288           |          |
|  APOL1 |  GC | 0.468 | 0.24           |          |
|  PTPRC |  GC | 0.468 | 0.168           |          |
|  APOC1 |  GC | 0.468 |            |          |
|  DYSF |  GC | 0.468 | 0.092           |          |
|  C5 |  HP | 0.455 | 0.328           |          |
|  C5 |  APOA1 | 0.455 | 0.348           |          |
|  C5 |  GC | 0.455 | 0.362           |          |
|  C5 |  FGA | 0.455 | 0.204           |          |
|  C5 |  SERPIND1 | 0.438 | 0.42           |          |
|  C5 |  C3 | 0.438 | 0.368           |          |
|  C5 |  FGG | 0.438 | 0.248           |          |
|  NCF2 |  SERPIND1 | 0.405 | 0.046           |          |
|  C5 |  TF | 0.404 | 0.288           |          |
|  DYSF |  APOA1 | 0.401 | 0.278           |          |
|  PTPRC |  FGA | 0.401 | 0.206           |          |
|  APOL1 |  FGA | 0.401 | 0.176           |          |
|  APOC1 |  APOA1 | 0.401 |            |          |
|  PTPRC |  APOA1 | 0.401 | 0.314           |          |
|  APOC1 |  FGA | 0.401 |            |          |
|  DYSF |  FGA | 0.401 | 0.264           |          |
|  APOL1 |  APOA1 | 0.401 | 0.178           |          |
|  PGLYRP1 |  GC | 0.401 |            |          |
|  DYSF |  HP | 0.378 | 0.118           |          |
|  APOC1 |  HP | 0.378 |            |          |
|  PTPRC |  HP | 0.378 | 0.208           |          |
|  APOL1 |  HP | 0.378 | 0.322           |          |
|  NCF2 |  APOA1 | 0.356 | 0.104           |          |
|  NCF2 |  FGA | 0.356 | 0.036           |          |
|  PGLYRP1 |  APOA1 | 0.356 |            |          |
|  NCF2 |  GC | 0.356 | 0.056           |          |
|  PGLYRP1 |  FGA | 0.356 |            |          |
|  NCF2 |  HP | 0.334 | 0.034           |          |
|  PGLYRP1 |  HP | 0.334 |            |
mutually_exclusive (P02763)        
|
|  C5 |  SERPINA3 | 0.274 | 0.31           |          |
|  PTPRC |  C3 | 0.255 | 0.43           |          |
|  PADI2 |  GC | 0.255 | 0.062           |          |
|  APOC1 |  C3 | 0.255 |            |          |
|  APOL1 |  C3 | 0.255 | 0.36           |          |
|  DYSF |  C3 | 0.255 | 0.19           |          |
|  DYSF |  TF | 0.22 | 0.3           |          |
|  APOL1 |  TF | 0.22 | 0.238           |          |
|  PTPRC |  TF | 0.22 | 0.471010752688           |          |
|  APOC1 |  TF | 0.22 |            |          |
|  PGLYRP1 |  TF | 0.22 |            |          |
|  APOC1 |  FGG | 0.22 |            |          |
|  PTPRC |  FGG | 0.22 | 0.175010752688           |          |
|  PGLYRP1 |  FGG | 0.22 |            |          |
|  DYSF |  FGG | 0.22 | 0.246           |          |
|  NCF2 |  C3 | 0.22 | 0.068           |          |
|  PGLYRP1 |  C3 | 0.22 |            |          |
|  APOL1 |  FGG | 0.22 | 0.262           |          |
|  OR6C70 |  PTPRC | 0.214 |            |          |
|  OR6C70 |  NCF2 | 0.214 |            |          |
|  C5 |  OR6C70 | 0.214 |            |          |
|  OR6C70 |  PADI2 | 0.214 |            |          |
|  OR6C70 |  APOC1 | 0.214 |            |          |
|  OR6C70 |  HPR | 0.214 |            |          |
|  OR6C70 |  APOL1 | 0.214 |            |          |
|  PGLYRP1 |  OR6C70 | 0.214 |            |          |
|  OR6C70 |  DYSF | 0.214 |            |          |
|  OR6C70 |  SERPIND1 | 0.214 |            |          |
|  NCF2 |  FGG | 0.205 | 0.072           |          |
|  NCF2 |  TF | 0.199 | 0.078328358209           |          |
|  PADI2 |  TF | 0.188 | 0.166317460317           |          |
|  PADI2 |  C3 | 0.188 | 0.154           |          |
|  PADI2 |  HP | 0.188 | 0.12           |          |
|  PADI2 |  APOA1 | 0.188 | 0.138636363636           |          |
|  PADI2 |  FGG | 0.188 | 0.07           |          |
|  PADI2 |  FGA | 0.188 | 0.036           |          |
|  OR6C70 |  GC | 0.055 |            |          |
|  OR6C70 |  HP | 0.043 |            |          |
|  OR6C70 |  APOA1 | 0.043 |            |          |
|  OR6C70 |  FGA | 0.043 |            |          |
|  OR6C70 |  C3 | 0.043 |            |          |
|  OR6C70 |  TF | 0.042 |            |          |
|  OR6C70 |  FGG | 0.042 |            |          |
Related Complexes