hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08241.1
Complex Portal: CPX-10948
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDAP1 | 28 kDa heat- and acid-stable phosphoprotein (PDGF-associated protein) (PAP) (PDGFA-associated protein 1) (PAP1) | 4 | UniProt NCBI |
| ABCF1 | ATP-binding cassette sub-family F member 1 (ATP-binding cassette 50) (TNF-alpha-stimulated ABC protein) | 5 | UniProt NCBI |
| RTRAF | RNA transcription, translation and transport factor protein (CLE7 homolog) (CLE) (hCLE) | 5 | UniProt NCBI |
| DEK | Protein DEK | 5 | UniProt NCBI |
| NEMF | Ribosome quality control complex subunit NEMF (Antigen NY-CO-1) (Nuclear export mediator factor) (Serologically defined colon cancer antigen 1) | 5 | UniProt NCBI |
| RTCB | RNA-splicing ligase RtcB homolog (EC 6.5.1.8) (3'-phosphate/5'-hydroxy nucleic acid ligase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6301 | 0.000170782642132 | 0.333333333333 | RTRAF RTCB | tRNA Splicing Ligase Complex |
| HPA:0130242 | 0.00850602329029 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | colon; peripheral nerve/ganglion[>=Medium] |
| HPA:0440342 | 0.0142822139719 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | skeletal muscle; myocytes[>=Medium] |
| HPA:0050092 | 0.0158607015262 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | breast; myoepithelial cells[>=Medium] |
| HPA:0340461 | 0.022484133991 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | ovary; ovarian stroma cells[>=Low] |
| HPA:0630052 | 0.02278471139 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | cervix; glandular cells[>=Medium] |
| HPA:0160251 | 0.0253947209828 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | endometrium 1; cells in endometrial stroma[>=Low] |
| HPA:0250132 | 0.0311695988487 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | hippocampus; neuronal cells[>=Medium] |
| HPA:0530721 | 0.0362409368932 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | spleen; cells in white pulp[>=Low] |
| HPA:0330222 | 0.0368007038962 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | oral mucosa; squamous epithelial cells[>=Medium] |
| REAC:R-HSA-6784531 | 0.0379731829042 | 0.333333333333 | RTRAF RTCB | tRNA processing in the nucleus |
| GO:0003723 | 0.0382588428658 | 1.0 | RTCB DEK RTRAF ABCF1 PDAP1 NEMF | RNA binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RTRAF | RTCB | 0.996 | 0.92 |
structurally_consistent (dimer)
|
hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| RTRAF | ABCF1 | 0.981 | 0.132 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| RTRAF | NEMF | 0.978 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PDAP1 | RTRAF | 0.977 | 0.12 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only | |
| DEK | RTRAF | 0.976 | 0.13 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| NEMF | RTCB | 0.973 | 0.162 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| DEK | RTCB | 0.97 | 0.118 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM | |
| PDAP1 | NEMF | 0.964 | 0.098 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| DEK | NEMF | 0.883 | 0.062 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| DEK | ABCF1 | 0.684 | 0.114 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PDAP1 | DEK | 0.679 | 0.156 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PDAP1 | RTCB | 0.498 | 0.08 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| NEMF | ABCF1 | 0.32 | 0.18 | bioplex_WMM bioplex3_WMM youn_WMM fraction | |
| ABCF1 | RTCB | 0.105 | 0.172 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM | |
| PDAP1 | ABCF1 | 0.063 | 0.214 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes