hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08257.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STEAP4 | Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9) | 5 | UniProt NCBI |
| ITGB2 | Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18) | 5 | UniProt NCBI |
| MMP12 | Macrophage metalloelastase (MME) (EC 3.4.24.65) (Macrophage elastase) (ME) (hME) (Matrix metalloproteinase-12) (MMP-12) | 5 | UniProt NCBI |
| SARAF | Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66) | 5 | UniProt NCBI |
| CFHR1 | Complement factor H-related protein 1 (FHR-1) (H factor-like protein 1) (FHL-1) (H-factor-like 1) (H36) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04610 | 0.0111896078643 | 0.4 | ITGB2 CFHR1 | Complement and coagulation cascades |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MMP12 | SARAF | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| CFHR1 | SARAF | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| STEAP4 | SARAF | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ITGB2 | SARAF | 0.97 | 0.062 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CFHR1 | MMP12 | 0.902 | bioplex3_WMM WMM_only | |
| STEAP4 | MMP12 | 0.902 | bioplex3_WMM WMM_only | |
| ITGB2 | MMP12 | 0.902 | bioplex3_WMM WMM_only | |
| CFHR1 | ITGB2 | 0.722 | bioplex3_WMM WMM_only | |
| STEAP4 | ITGB2 | 0.626 | 0.144 | bioplex3_WMM WMM_only |
| CFHR1 | STEAP4 | 0.602 | bioplex3_WMM WMM_only |
Related Complexes