hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08270.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RNF170 | E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170) | 5 | UniProt NCBI |
| DUSP3 | Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase VHR) (Vaccinia H1-related phosphatase) (VHR) | 5 | UniProt NCBI |
| ERLIN2 | Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6476 | 1.02521027753e-05 | 0.666666666667 | ERLIN2 RNF170 | erlin1/2-RNF170 complex |
| HP:0006986 | 0.00319841341764 | 0.666666666667 | ERLIN2 RNF170 | Upper limb spasticity |
| HP:0000763 | 0.047155317063 | 0.666666666667 | ERLIN2 RNF170 | Sensory neuropathy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ERLIN2 | RNF170 | 0.998 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ERLIN2 | DUSP3 | 0.995 | 0.044 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| DUSP3 | RNF170 | 0.985 | 0.036 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes