hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08287.1
Complex Portal: CPX-19571
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| OTUD3 | OTU domain-containing protein 3 (EC 3.4.19.12) | 5 | UniProt NCBI |
| GNAT3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 (Gustducin alpha-3 chain) | 5 | UniProt NCBI |
| HRAS | GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9009391 | 0.0128584085686 | 0.666666666667 | GNAT3 HRAS | Extra-nuclear estrogen signaling |
| CORUM:5922 | 0.0499402709677 | 0.333333333333 | HRAS | RAF1-RAS complex, EGF induced |
| CORUM:6219 | 0.0499402709677 | 0.333333333333 | HRAS | DGKZ-RASGRP1-HRAS complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| OTUD3 | GNAT3 | 0.998 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| OTUD3 | HRAS | 0.984 | 0.296 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GNAT3 | HRAS | 0.297 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes