hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08296.1
Complex Portal: CPX-17165
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SH2D3C | SH2 domain-containing protein 3C (Cas/HEF1-associated signal transducer) (Chat-H) (Novel SH2-containing protein 3) (SH2 domain-containing Eph receptor-binding protein 1) (SHEP1) | 5 | UniProt NCBI |
| NEDD9 | Enhancer of filamentation 1 (hEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (Cas scaffolding protein family member 2) (CASS2) (Neural precursor cell expressed developmentally down-regulated protein 9) (NEDD-9) (Renal carcinoma antigen NY-REN-12) (p105) [Cleaved into: Enhancer of filamentation 1 p55] | 5 | UniProt NCBI |
| BCAR1 | Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP366 | 0.00791054256456 | 0.666666666667 | NEDD9 BCAR1 | TGF beta signaling pathway |
| CORUM:5282 | 0.0499402709677 | 0.333333333333 | BCAR1 | CAS-SRC-FAK complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SH2D3C | BCAR1 | 0.999 | 0.094 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BCAR1 | NEDD9 | 0.976 | 0.152 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SH2D3C | NEDD9 | 0.415 | 0.114 | bioplex3_WMM WMM_only |
Related Complexes