hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08299.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DOCK3 | Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP) | 5 | UniProt NCBI |
| HS3ST2 | Heparan sulfate glucosamine 3-O-sulfotransferase 2 (EC 2.8.2.29) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2) (3-OST-2) (Heparan sulfate 3-O-sulfotransferase 2) (h3-OST-2) | 5 | UniProt NCBI |
| HS3ST4 | Heparan sulfate glucosamine 3-O-sulfotransferase 4 (EC 2.8.2.23) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4) (3-OST-4) (Heparan sulfate 3-O-sulfotransferase 4) (h3-OST-4) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2022928 | 0.00257431960226 | 0.666666666667 | HS3ST2 HS3ST4 | HS-GAG biosynthesis |
| REAC:R-HSA-1638091 | 0.00833431912959 | 0.666666666667 | HS3ST2 HS3ST4 | Heparan sulfate/heparin (HS-GAG) metabolism |
| WP:WP702 | 0.0101834993772 | 0.666666666667 | HS3ST2 HS3ST4 | Metapathway biotransformation Phase I and II |
| GO:0008467 | 0.0140440992017 | 0.666666666667 | HS3ST2 HS3ST4 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
| REAC:R-HSA-1630316 | 0.0406752460979 | 0.666666666667 | HS3ST2 HS3ST4 | Glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HS3ST2 | HS3ST4 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DOCK3 | HS3ST4 | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only |
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