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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_08306.1
Complex Portal:
CPX-15507
Confidence:
High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
LRP1
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
5
UniProt
NCBI
LRP2
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
5
UniProt
NCBI
LRP8
Low-density lipoprotein receptor-related protein 8 (LRP-8) (Apolipoprotein E receptor 2)
5
UniProt
NCBI
LRPAP1
Alpha-2-macroglobulin receptor-associated protein (Alpha-2-MRAP) (Low density lipoprotein receptor-related protein-associated protein 1) (RAP)
5
UniProt
NCBI
Showing 1 to 4 of 4 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
KEGG:04979
3.65228974203e-06
0.75
LRP2 LRP1 LRPAP1
Cholesterol metabolism
REAC:R-HSA-975634
1.38374083551e-05
0.75
LRP2 LRP1 LRP8
Retinoid metabolism and transport
REAC:R-HSA-6806667
1.72814889866e-05
0.75
LRP2 LRP1 LRP8
Metabolism of fat-soluble vitamins
REAC:R-HSA-2187338
0.000106339832101
0.75
LRP2 LRP1 LRP8
Visual phototransduction
GO:0005041
0.000139871762976
0.75
LRP2 LRP1 LRP8
low-density lipoprotein particle receptor activity
GO:0045056
0.000174830724535
0.75
LRP2 LRP1 LRPAP1
transcytosis
GO:0030228
0.000215165225046
0.75
LRP2 LRP1 LRP8
lipoprotein particle receptor activity
REAC:R-HSA-196854
0.000880808650283
0.75
LRP2 LRP1 LRP8
Metabolism of vitamins and cofactors
GO:0097242
0.00190418300832
0.75
LRP2 LRP1 LRPAP1
amyloid-beta clearance
REAC:R-HSA-9709957
0.002052480752
0.75
LRP2 LRP1 LRP8
Sensory Perception
Showing 1 to 10 of 21 entries
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Interface Overlap
?
Evidence
?
LRP2
LRPAP1
0.99
0.092
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRP8
LRPAP1
0.979
0.058
structurally_consistent (dimer)
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRPAP1
LRP1
0.96
0.112
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
LRP2
LRP1
0.575
0.254
bioplex_WMM bioplex3_WMM WMM_only
LRP8
LRP1
0.111
0.152
bioplex_WMM bioplex3_WMM WMM_only
LRP8
LRP2
0.066
0.086
bioplex_WMM bioplex3_WMM gupta_WMM WMM_only
Showing 1 to 6 of 6 entries
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Related Complexes
Genename
Complexes
LRP2
huMAP3_01857.1
huMAP3_02751.1
huMAP3_05672.1
huMAP3_06423.1
huMAP3_06436.1
huMAP3_07892.1
huMAP3_08306.1
huMAP3_10228.1
huMAP3_10712.1
LRP1
huMAP3_02751.1
huMAP3_05672.1
huMAP3_06423.1
huMAP3_08306.1
huMAP3_10228.1
huMAP3_10712.1
huMAP3_11525.1
huMAP3_13632.1
LRP8
huMAP3_00485.1
huMAP3_02751.1
huMAP3_05013.1
huMAP3_05672.1
huMAP3_05926.1
huMAP3_06423.1
huMAP3_06930.1
huMAP3_07676.1
huMAP3_08247.1
huMAP3_08306.1
huMAP3_10228.1
huMAP3_10712.1
huMAP3_10755.1
huMAP3_13100.1
LRPAP1
huMAP3_02751.1
huMAP3_05672.1
huMAP3_06423.1
huMAP3_08306.1
huMAP3_10228.1
huMAP3_10712.1
huMAP3_13192.1