hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08312.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LTBR | Tumor necrosis factor receptor superfamily member 3 (Lymphotoxin-beta receptor) (Tumor necrosis factor C receptor) (Tumor necrosis factor receptor 2-related protein) (Tumor necrosis factor receptor type III) (TNF-RIII) (TNFR-III) | 5 | UniProt NCBI |
| TCHP | Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein) | 5 | UniProt NCBI |
| BIRC3 | Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1) | 5 | UniProt NCBI |
| CCDC121 | Coiled-coil domain-containing protein 121 | 2 | UniProt NCBI |
| PRC1 | Protein regulator of cytokinesis 1 | 5 | UniProt NCBI |
| CCDC113 | Coiled-coil domain-containing protein 113 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5676594 | 0.0014177632075 | 0.333333333333 | LTBR BIRC3 | TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway |
| KEGG:04064 | 0.0226487502466 | 0.333333333333 | LTBR BIRC3 | NF-kappa B signaling pathway |
| CORUM:5530 | 0.0499436884912 | 0.166666666667 | LTBR | LTBR homodimer complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CCDC121 | LTBR | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CCDC113 | LTBR | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BIRC3 | LTBR | 0.991 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TCHP | LTBR | 0.985 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PRC1 | LTBR | 0.97 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| CCDC113 | CCDC121 | 0.513 | bioplex_WMM bioplex3_WMM WMM_only | |
| TCHP | CCDC121 | 0.513 | bioplex_WMM bioplex3_WMM WMM_only | |
| CCDC113 | TCHP | 0.378 | bioplex_WMM bioplex3_WMM WMM_only | |
| CCDC113 | PRC1 | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| PRC1 | CCDC121 | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| BIRC3 | CCDC121 | 0.146 | bioplex3_WMM WMM_only | |
| CCDC113 | BIRC3 | 0.131 | bioplex3_WMM WMM_only | |
| PRC1 | TCHP | 0.062 | 0.07 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| BIRC3 | TCHP | 0.055 | bioplex3_WMM WMM_only | |
| BIRC3 | PRC1 | 0.042 | bioplex3_WMM WMM_only |
Related Complexes