hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08316.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ADAR | Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP) | 5 | UniProt NCBI |
| DDX3Y | ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal) | 5 | UniProt NCBI |
| ADARB1 | Double-stranded RNA-specific editase 1 (EC 3.5.4.37) (RNA-editing deaminase 1) (RNA-editing enzyme 1) (dsRNA adenosine deaminase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-75102 | 6.81845708859e-06 | 0.666666666667 | ADAR ADARB1 | C6 deamination of adenosine |
| REAC:R-HSA-77042 | 6.81845708859e-06 | 0.666666666667 | ADAR ADARB1 | Formation of editosomes by ADAR proteins |
| REAC:R-HSA-75064 | 6.81845708859e-06 | 0.666666666667 | ADAR ADARB1 | mRNA Editing: A to I Conversion |
| REAC:R-HSA-75072 | 0.000102258192243 | 0.666666666667 | ADAR ADARB1 | mRNA Editing |
| GO:0003726 | 0.00421361424067 | 0.666666666667 | ADAR ADARB1 | double-stranded RNA adenosine deaminase activity |
| GO:0008251 | 0.00842684400117 | 0.666666666667 | ADAR ADARB1 | tRNA-specific adenosine deaminase activity |
| GO:0006382 | 0.0140440992017 | 0.666666666667 | ADAR ADARB1 | adenosine to inosine editing |
| GO:0044387 | 0.0210651876021 | 0.666666666667 | ADAR ADARB1 | negative regulation of protein kinase activity by regulation of protein phosphorylation |
| GO:0004000 | 0.0294899169624 | 0.666666666667 | ADAR ADARB1 | adenosine deaminase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ADAR | ADARB1 | 0.977 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM treiber_WMM WMM_only | |
| DDX3Y | ADAR | 0.954 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM | |
| DDX3Y | ADARB1 | 0.033 | 0.07 | hein_WMM WMM_only treiber_WMM |
Related Complexes