hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08323.1

Complex Portal: CPX-14694

Confidence: High

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Genename	Protein Name	Uniprot Annotation Score	Links
ACVR1B	Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)	5	UniProt NCBI
ACVR2B	Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)	5	UniProt NCBI

Showing 1 to 2 of 2 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1433617	6.15154230766e-05	1.0	ACVR2B ACVR1B	Regulation of signaling by NODAL
REAC:R-HSA-1502540	7.68942788458e-05	1.0	ACVR2B ACVR1B	Signaling by Activin
REAC:R-HSA-1181150	0.000261440548076	1.0	ACVR2B ACVR1B	Signaling by NODAL
KEGG:04350	0.000608173227025	1.0	ACVR2B ACVR1B	TGF-beta signaling pathway
KEGG:04550	0.00116074761854	1.0	ACVR2B ACVR1B	Signaling pathways regulating pluripotency of stem cells
KEGG:04060	0.0031385705215	1.0	ACVR2B ACVR1B	Cytokine-cytokine receptor interaction
GO:0048179	0.00468200720083	1.0	ACVR2B ACVR1B	activin receptor complex
GO:0032927	0.00468200720083	1.0	ACVR2B ACVR1B	positive regulation of activin receptor signaling pathway
GO:0048185	0.00983221512175	1.0	ACVR2B ACVR1B	activin binding
REAC:R-HSA-9006936	0.0098732254038	1.0	ACVR2B ACVR1B	Signaling by TGFB family members

Showing 1 to 10 of 14 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
ACVR2B	ACVR1B	0.994		structurally_consistent (dimer)	bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only

Showing 1 to 1 of 1 entries

Related Complexes

Genename	Complexes
ACVR2B	huMAP3_00655.1 huMAP3_00866.1 huMAP3_04581.1 huMAP3_06211.1 huMAP3_08323.1 huMAP3_09249.1 huMAP3_10877.1 huMAP3_11149.1 huMAP3_11605.1 huMAP3_14203.1
ACVR1B	huMAP3_02078.1 huMAP3_07383.1 huMAP3_08323.1 huMAP3_09144.1 huMAP3_10877.1 huMAP3_11149.1 huMAP3_11556.1 huMAP3_11605.1