hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
ACVR2B	Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)	5	UniProt NCBI
ACVR1B	Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1433617	6.15154230766e-05	1.0	ACVR2B ACVR1B	Regulation of signaling by NODAL
REAC:R-HSA-1502540	7.68942788458e-05	1.0	ACVR2B ACVR1B	Signaling by Activin
REAC:R-HSA-1181150	0.000261440548076	1.0	ACVR2B ACVR1B	Signaling by NODAL
KEGG:04350	0.000608173227025	1.0	ACVR2B ACVR1B	TGF-beta signaling pathway
KEGG:04550	0.00116074761854	1.0	ACVR2B ACVR1B	Signaling pathways regulating pluripotency of stem cells
KEGG:04060	0.0031385705215	1.0	ACVR2B ACVR1B	Cytokine-cytokine receptor interaction
GO:0048179	0.00468200720083	1.0	ACVR2B ACVR1B	activin receptor complex
GO:0032927	0.00468200720083	1.0	ACVR2B ACVR1B	positive regulation of activin receptor signaling pathway
GO:0048185	0.00983221512175	1.0	ACVR2B ACVR1B	activin binding
REAC:R-HSA-9006936	0.0098732254038	1.0	ACVR2B ACVR1B	Signaling by TGFB family members
GO:0017002	0.0131096201623	1.0	ACVR2B ACVR1B	activin receptor activity
GO:0004675	0.0426062655276	1.0	ACVR2B ACVR1B	transmembrane receptor protein serine/threonine kinase activity
HP:0010452	0.0499436884913	0.5	ACVR2B	Ectopia of the spleen
HP:0034188	0.0499436884913	0.5	ACVR2B	Midline liver

Protein 1	Protein 2	Score	ProteomeHD	Evidence
ACVR2B	ACVR1B	0.994		bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only

Genename	Complexes
ACVR2B	huMAP3_00655.1 huMAP3_00866.1 huMAP3_04581.1 huMAP3_06211.1 huMAP3_08323.1 huMAP3_09249.1 huMAP3_10877.1 huMAP3_11149.1 huMAP3_11605.1 huMAP3_14203.1
ACVR1B	huMAP3_02078.1 huMAP3_07383.1 huMAP3_08323.1 huMAP3_09144.1 huMAP3_10877.1 huMAP3_11149.1 huMAP3_11556.1 huMAP3_11605.1