hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08330.1
Confidence: High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ORMDL3 | ORM1-like protein 3 | 5 | UniProt   NCBI |
ORMDL2 | ORM1-like protein 2 (Adoplin-2) | 5 | UniProt   NCBI |
SLC5A5 | Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-1660661 | 0.00381957013228 | 0.666666666667 | ORMDL2 ORMDL3 | Sphingolipid de novo biosynthesis |
  GO:0035339 | 0.00842684400117 | 0.666666666667 | ORMDL2 ORMDL3 | SPOTS complex |
  GO:0090156 | 0.00842684400117 | 0.666666666667 | ORMDL2 ORMDL3 | intracellular sphingolipid homeostasis |
  GO:1900060 | 0.0140440992017 | 0.666666666667 | ORMDL2 ORMDL3 | negative regulation of ceramide biosynthetic process |
  REAC:R-HSA-428157 | 0.0178608636553 | 0.666666666667 | ORMDL2 ORMDL3 | Sphingolipid metabolism |
  GO:0017059 | 0.0210651876021 | 0.666666666667 | ORMDL2 ORMDL3 | serine C-palmitoyltransferase complex |
  GO:0031211 | 0.0210651876021 | 0.666666666667 | ORMDL2 ORMDL3 | endoplasmic reticulum palmitoyltransferase complex |
  GO:0090155 | 0.0210651876021 | 0.666666666667 | ORMDL2 ORMDL3 | negative regulation of sphingolipid biosynthetic process |
  HPA:0120233 | 0.0282719715809 | 0.333333333333 | SLC5A5 | choroid plexus; ependymal cells[High] |
  REAC:R-HSA-5619096 | 0.0498224659464 | 0.333333333333 | SLC5A5 | Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) |
  CORUM:6982 | 0.0499402709677 | 0.333333333333 | ORMDL3 | ORMDL3-SPTLC1 complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 ORMDL2 |  ORMDL3 | 0.988 | 0.262           | bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     gupta_WMM     WMM_only     |
 SLC5A5 |  ORMDL2 | 0.95 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes