hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08335.1
Complex Portal: CPX-14853
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DCUN1D5 | DCN1-like protein 5 (DCNL5) (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5) (Squamous cell carcinoma-related oncogene 5) | 5 | UniProt NCBI |
| WDHD1 | WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA-binding protein 1) (And-1) | 5 | UniProt NCBI |
| DGKA | Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (EC 2.7.1.93) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha) | 5 | UniProt NCBI |
| PSD3 | PH and SEC7 domain-containing protein 3 (Epididymis tissue protein Li 20mP) (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 D) (Exchange factor for ARF6 D) (Hepatocellular carcinoma-associated antigen 67) (Pleckstrin homology and SEC7 domain-containing protein 3) | 5 | UniProt NCBI |
| SMARCAL1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.4.-) (HepA-related protein) (hHARP) (Sucrose nonfermenting protein 2-like 1) | 5 | UniProt NCBI |
| WNK2 | Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Antigen NY-CO-43) (Protein kinase lysine-deficient 2) (Protein kinase with no lysine 2) (Serologically defined colon cancer antigen 43) | 5 | UniProt NCBI |
| USP48 | Ubiquitin carboxyl-terminal hydrolase 48 (EC 3.4.19.12) (Deubiquitinating enzyme 48) (Ubiquitin thioesterase 48) (Ubiquitin-specific peptidase 48) (Ubiquitin-specific protease 48) (Ubiquitin-specific-processing protease 48) | 5 | UniProt NCBI |
| RINL | Ras and Rab interactor-like protein | 3 | UniProt NCBI |
| EEF1AKMT3 | EEF1A lysine methyltransferase 3 (EC 2.1.1.-) (Hepatocellular carcinoma-associated antigen 557a) (Methyltransferase-like protein 21B) (Protein-lysine methyltransferase METTL21B) (eEF1A-KMT3) | 5 | UniProt NCBI |
| GRB7 | Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein) | 5 | UniProt NCBI |
| EYA3 | Eyes absent homolog 3 (EC 3.1.3.48) | 5 | UniProt NCBI |
| ABR | Active breakpoint cluster region-related protein | 5 | UniProt NCBI |
| ZC3H7B | Zinc finger CCCH domain-containing protein 7B (Rotavirus 'X'-associated non-structural protein) (RoXaN) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| WNK2 | EEF1AKMT3 | 0.999 | ||
| RINL | EEF1AKMT3 | 0.999 | ||
| EEF1AKMT3 | PSD3 | 0.998 | ||
| EEF1AKMT3 | ABR | 0.998 | ||
| DGKA | EEF1AKMT3 | 0.998 | ||
| EEF1AKMT3 | ZC3H7B | 0.998 | ||
| USP48 | EEF1AKMT3 | 0.998 | ||
| EEF1AKMT3 | GRB7 | 0.997 | ||
| EEF1AKMT3 | EYA3 | 0.996 |
structurally_consistent (dimer)
|
|
| EEF1AKMT3 | WDHD1 | 0.995 | ||
| EEF1AKMT3 | SMARCAL1 | 0.995 | ||
| EEF1AKMT3 | DCUN1D5 | 0.993 |
structurally_consistent (dimer)
|
|
| DGKA | ZC3H7B | 0.902 | 0.074 | |
| GRB7 | ZC3H7B | 0.902 | 0.088 | |
| RINL | GRB7 | 0.902 | 0.114 | |
| DGKA | GRB7 | 0.902 | 0.094 | |
| DGKA | RINL | 0.902 | 0.064 | |
| GRB7 | PSD3 | 0.902 | 0.076 | |
| DGKA | PSD3 | 0.902 | 0.03 | |
| RINL | PSD3 | 0.902 | ||
| DGKA | ABR | 0.902 | 0.036 | |
| GRB7 | ABR | 0.902 | 0.202 | |
| RINL | EYA3 | 0.892 | 0.078 | |
| DGKA | EYA3 | 0.892 | 0.044 | |
| GRB7 | EYA3 | 0.892 | 0.076 | |
| USP48 | DCUN1D5 | 0.892 | 0.1 | |
| WNK2 | GRB7 | 0.869 | 0.128 | |
| DGKA | WNK2 | 0.869 | 0.05 | |
| WNK2 | ZC3H7B | 0.869 | 0.068 | |
| WNK2 | RINL | 0.869 | ||
| RINL | ZC3H7B | 0.796 | 0.07 | |
| USP48 | RINL | 0.768 | 0.106 | |
| USP48 | GRB7 | 0.768 | 0.106 | |
| USP48 | ZC3H7B | 0.768 | 0.038 | |
| DGKA | USP48 | 0.768 | 0.04 | |
| ZC3H7B | SMARCAL1 | 0.73 | 0.046 | |
| GRB7 | SMARCAL1 | 0.73 | 0.074 | |
| RINL | SMARCAL1 | 0.73 | 0.092 | |
| DGKA | SMARCAL1 | 0.73 | 0.028 | |
| GRB7 | WDHD1 | 0.715 | 0.124 | |
| RINL | WDHD1 | 0.715 | 0.114 | |
| DGKA | WDHD1 | 0.715 | 0.086 | |
| WNK2 | EYA3 | 0.675 | 0.028 | |
| DGKA | DCUN1D5 | 0.675 | 0.034 | |
| GRB7 | DCUN1D5 | 0.675 | 0.116 | |
| ZC3H7B | DCUN1D5 | 0.675 | 0.052 | |
| ABR | DCUN1D5 | 0.675 | 0.046 | |
| EYA3 | SMARCAL1 | 0.675 | 0.124 | |
| WNK2 | USP48 | 0.675 | 0.068 | |
| RINL | DCUN1D5 | 0.675 | 0.046 | |
| EYA3 | ZC3H7B | 0.667 | 0.03 | |
| RINL | ABR | 0.661 | 0.078 | |
| ZC3H7B | PSD3 | 0.661 | 0.082 | |
| USP48 | EYA3 | 0.59 | 0.09 | |
| EYA3 | DCUN1D5 | 0.552 | 0.122 |
mutually_exclusive (Q96AZ1)
|
| WNK2 | DCUN1D5 | 0.548 | 0.054 | |
| ZC3H7B | ABR | 0.542 | 0.102 | |
| WNK2 | PSD3 | 0.522 | 0.132 | |
| WNK2 | SMARCAL1 | 0.499 | 0.064 | |
| EYA3 | WDHD1 | 0.421 | 0.112 | |
| EYA3 | PSD3 | 0.388 | 0.062 | |
| WNK2 | ABR | 0.388 | 0.078 | |
| USP48 | PSD3 | 0.364 | 0.082 | |
| PSD3 | SMARCAL1 | 0.356 | 0.072 | |
| ABR | SMARCAL1 | 0.343 | 0.012 | |
| USP48 | SMARCAL1 | 0.323 | 0.052 | |
| PSD3 | DCUN1D5 | 0.321 | 0.064 | |
| WNK2 | WDHD1 | 0.317 | 0.064 | |
| EYA3 | ABR | 0.312 | 0.044 | |
| SMARCAL1 | WDHD1 | 0.267 | 0.076 | |
| DCUN1D5 | SMARCAL1 | 0.251 | 0.036 | |
| USP48 | ABR | 0.236 | 0.038 | |
| PSD3 | ABR | 0.236 | 0.034 | |
| DCUN1D5 | WDHD1 | 0.235 | 0.048 | |
| USP48 | WDHD1 | 0.211 | 0.084 | |
| ZC3H7B | WDHD1 | 0.18 | 0.032 | |
| PSD3 | WDHD1 | 0.178 | 0.056 | |
| ABR | WDHD1 | 0.081 | 0.056 |
Related Complexes