hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
PUM2	Pumilio homolog 2 (Pumilio-2)	5	UniProt NCBI
UPF1	Regulator of nonsense transcripts 1 (EC 3.6.4.12) (EC 3.6.4.13) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1)	5	UniProt NCBI
RBMS1	RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2)	5	UniProt NCBI
SZRD1	SUZ domain-containing protein 1 (Putative MAPK-activating protein PM18/PM20/PM22)	3	UniProt NCBI
PUM1	Pumilio homolog 1 (HsPUM) (Pumilio-1)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0061158	0.000174830724535	0.75	PUM1 PUM2 UPF1	3'-UTR-mediated mRNA destabilization
KEGG:05017	0.0192212154966	0.5	PUM2 PUM1	Spinocerebellar ataxia
GO:0061157	0.0434703685672	0.75	PUM1 PUM2 UPF1	mRNA destabilization
GO:0050779	0.048062454325	0.75	PUM1 PUM2 UPF1	RNA destabilization
GO:0061014	0.0496619752722	0.75	PUM1 PUM2 UPF1	positive regulation of mRNA catabolic process

Protein 1	Protein 2	Score	ProteomeHD	Evidence
PUM2	UPF1	0.988		hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM
PUM1	UPF1	0.985	0.35	youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only
PUM2	PUM1	0.983		youn () bioplex_WMM bioplex3_WMM youn_WMM treiber_WMM WMM_only
RBMS1	UPF1	0.972	0.2524	youn () bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only
SZRD1	UPF1	0.955	0.21	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
PUM2	RBMS1	0.663		youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only
PUM1	RBMS1	0.501	0.168	youn () bioplex_WMM bioplex3_WMM youn_WMM boldt_WMM treiber_WMM WMM_only
PUM1	SZRD1	0.005	0.126	youn_WMM fraction

Genename	Complexes
PUM2	huMAP3_00039.1 huMAP3_03682.1 huMAP3_05745.1 huMAP3_05758.1 huMAP3_06196.1 huMAP3_06975.1 huMAP3_07115.1 huMAP3_07589.1 huMAP3_07939.1 huMAP3_08105.1 huMAP3_08338.1 huMAP3_09095.1 huMAP3_09113.1 huMAP3_09186.1 huMAP3_09223.1 huMAP3_09317.1 huMAP3_10091.1 huMAP3_10114.1 huMAP3_10625.1 huMAP3_10905.1 huMAP3_11032.1
UPF1	huMAP3_01658.1 huMAP3_05758.1 huMAP3_06975.1 huMAP3_08338.1 huMAP3_08686.1 huMAP3_10625.1 huMAP3_10905.1
RBMS1	huMAP3_01658.1 huMAP3_04085.1 huMAP3_05043.1 huMAP3_05758.1 huMAP3_07183.1 huMAP3_08338.1 huMAP3_08686.1 huMAP3_10114.1 huMAP3_10625.1 huMAP3_10905.1
SZRD1	huMAP3_01658.1 huMAP3_03627.1 huMAP3_05758.1 huMAP3_08338.1 huMAP3_09986.1 huMAP3_10905.1 huMAP3_15264.1
PUM1	huMAP3_00582.1 huMAP3_03682.1 huMAP3_05538.1 huMAP3_05758.1 huMAP3_06975.1 huMAP3_07115.1 huMAP3_07846.1 huMAP3_08338.1 huMAP3_09223.1 huMAP3_10625.1 huMAP3_10905.1 huMAP3_13164.1