hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08357.1
Complex Portal: CPX-14892
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDC14A | Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) | 5 | UniProt NCBI |
| SACS | Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) | 5 | UniProt NCBI |
| LRIG1 | Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) | 5 | UniProt NCBI |
| SPSB4 | SPRY domain-containing SOCS box protein 4 (SSB-4) | 5 | UniProt NCBI |
| PCDH18 | Protocadherin-18 | 4 | UniProt NCBI |
| CD9 | CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9) | 5 | UniProt NCBI |
| SPSB1 | SPRY domain-containing SOCS box protein 1 (SSB-1) | 5 | UniProt NCBI |
| ACSM3 | Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) | 5 | UniProt NCBI |
| LRIG3 | Leucine-rich repeats and immunoglobulin-like domains protein 3 (LIG-3) | 4 | UniProt NCBI |
| SIK2 | Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) | 5 | UniProt NCBI |
| SH2B1 | SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B) | 5 | UniProt NCBI |
| TTC1 | Tetratricopeptide repeat protein 1 (TPR repeat protein 1) | 4 | UniProt NCBI |
| PARG | Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2370 | 0.0499717467432 | 0.0769230769231 | CD9 | ITGA2B-ITGB3-CD9 complex |
| CORUM:2770 | 0.0499717467432 | 0.0769230769231 | CD9 | ITGA6-ITGB4-CD9 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| LRIG1 | LRIG3 | 0.999 | ||
| SPSB4 | ACSM3 | 0.998 | ||
| SPSB4 | SIK2 | 0.997 | ||
| SPSB1 | TTC1 | 0.994 | ||
| SACS | SPSB4 | 0.993 | ||
| SPSB4 | CD9 | 0.988 | ||
| SPSB4 | SPSB1 | 0.987 | ||
| CDC14A | SPSB4 | 0.985 | ||
| SPSB4 | TTC1 | 0.983 | ||
| SPSB4 | SH2B1 | 0.975 | ||
| SPSB4 | LRIG3 | 0.975 | ||
| SPSB4 | LRIG1 | 0.974 | ||
| SPSB4 | PARG | 0.973 | ||
| PCDH18 | SPSB4 | 0.96 | ||
| ACSM3 | TTC1 | 0.825 | 0.066 | |
| ACSM3 | LRIG1 | 0.813 | 0.064 | |
| ACSM3 | LRIG3 | 0.81 | ||
| SACS | SIK2 | 0.78 | 0.05 | |
| SACS | ACSM3 | 0.757 | 0.028 | |
| SACS | LRIG3 | 0.752 | ||
| TTC1 | LRIG3 | 0.752 | ||
| ACSM3 | SIK2 | 0.72 | 0.088 | |
| SIK2 | LRIG1 | 0.608 | 0.072 | |
| SACS | LRIG1 | 0.608 | 0.036 | |
| SIK2 | TTC1 | 0.49 | 0.094 | |
| SPSB1 | ACSM3 | 0.415 | ||
| SPSB1 | SH2B1 | 0.415 | ||
| SPSB1 | PARG | 0.415 | ||
| ACSM3 | PARG | 0.415 | 0.072 | |
| CDC14A | SPSB1 | 0.415 | ||
| SH2B1 | PARG | 0.415 | 0.09 | |
| CDC14A | PARG | 0.415 | ||
| SACS | PARG | 0.415 | 0.034 | |
| CDC14A | SH2B1 | 0.415 | ||
| PCDH18 | PARG | 0.415 | ||
| SIK2 | LRIG3 | 0.389 | ||
| SACS | TTC1 | 0.319 | 0.006 | |
| ACSM3 | SH2B1 | 0.274 | 0.054 | |
| CDC14A | ACSM3 | 0.274 | ||
| SIK2 | PARG | 0.274 | 0.064 | |
| PCDH18 | SPSB1 | 0.274 | ||
| TTC1 | LRIG1 | 0.256 | 0.086 | |
| SACS | SPSB1 | 0.25 | ||
| SIK2 | CD9 | 0.156 | 0.034 | |
| SACS | CD9 | 0.137 | 0.052 | |
| ACSM3 | CD9 | 0.122 | 0.066 | |
| PARG | LRIG3 | 0.116 | ||
| CDC14A | SACS | 0.113 | ||
| SACS | SH2B1 | 0.113 | 0.04 | |
| PCDH18 | CDC14A | 0.113 | ||
| PCDH18 | SH2B1 | 0.113 | ||
| SPSB1 | SIK2 | 0.113 | ||
| PARG | LRIG1 | 0.102 | 0.05 | |
| TTC1 | PARG | 0.102 | 0.056 | |
| PCDH18 | ACSM3 | 0.095 | ||
| PCDH18 | SACS | 0.078 | ||
| CDC14A | SIK2 | 0.078 | ||
| SIK2 | SH2B1 | 0.078 | 0.116 | |
| PARG | CD9 | 0.076 | 0.028 | |
| PCDH18 | SIK2 | 0.076 | ||
| SPSB1 | CD9 | 0.076 | ||
| SPSB1 | LRIG1 | 0.076 | ||
| SPSB1 | LRIG3 | 0.074 | ||
| CDC14A | LRIG1 | 0.071 | ||
| SH2B1 | LRIG1 | 0.071 | 0.096 | |
| SH2B1 | TTC1 | 0.071 | 0.058 | |
| CDC14A | TTC1 | 0.071 | ||
| PCDH18 | LRIG1 | 0.063 | ||
| CDC14A | CD9 | 0.059 | ||
| SH2B1 | CD9 | 0.059 | 0.064 | |
| TTC1 | CD9 | 0.057 | 0.102 | |
| PCDH18 | CD9 | 0.055 | ||
| LRIG1 | CD9 | 0.054 | 0.084 | |
| CDC14A | LRIG3 | 0.054 | ||
| SH2B1 | LRIG3 | 0.054 | ||
| PCDH18 | TTC1 | 0.046 | ||
| PCDH18 | LRIG3 | 0.043 | ||
| LRIG3 | CD9 | 0.043 |
Related Complexes