hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08363.1
Complex Portal: CPX-17597
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FCGRT | IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor) | 5 | UniProt NCBI |
| B2M | Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3] | 5 | UniProt NCBI |
| GTF2E1 | General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012065 | 0.0499436884913 | 0.5 | B2M | Multiple bony cystic lesions |
| HP:0025044 | 0.0499436884913 | 0.5 | B2M | Lung abscess |
| HP:0033670 | 0.0499436884913 | 0.5 | B2M | Organizing pneumonia |
| HP:0100292 | 0.0499436884913 | 0.5 | B2M | Amyloidosis of peripheral nerves |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| B2M | FCGRT | 0.997 | 0.307 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FCGRT | GTF2E1 | 0.991 | 0.046 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| B2M | GTF2E1 | 0.165 | 0.01 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes