hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08365.1

Complex Portal: CPX-18509

Confidence: High

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Genename	Protein Name	Uniprot Annotation Score	Links
ACIN1	Apoptotic chromatin condensation inducer in the nucleus (Acinus)	5	UniProt NCBI
CWC22	Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb)	5	UniProt NCBI
EPB41L2	Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)	5	UniProt NCBI
GPATCH8	G patch domain-containing protein 8	4	UniProt NCBI
NKTR	NK-tumor recognition protein (NK-TR protein) (Natural-killer cells cyclophilin-related protein) (Peptidyl-prolyl cis-trans isomerase NKTR) (PPIase) (EC 5.2.1.8) (Rotamase)	5	UniProt NCBI
PRPF4B	Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)	5	UniProt NCBI
RNPS1	RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)	5	UniProt NCBI
RSBN1L	Lysine-specific demethylase RSBN1L (EC 1.14.11.-) (Round spermatid basic protein 1-like protein)	3	UniProt NCBI
SAP18	Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)	5	UniProt NCBI
SETD2	Histone-lysine N-methyltransferase SETD2 (EC 2.1.1.359) (HIF-1) (Huntingtin yeast partner B) (Huntingtin-interacting protein 1) (HIP-1) (Huntingtin-interacting protein B) (Lysine N-methyltransferase 3A) (Protein-lysine N-methyltransferase SETD2) (EC 2.1.1.-) (SET domain-containing protein 2) (hSET2) (p231HBP)	5	UniProt NCBI

Showing 1 to 10 of 12 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:760	2.5725558439e-08	0.25	RNPS1 SAP18 ACIN1	Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L
REAC:R-HSA-72163	1.47221997734e-06	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	1.80802915765e-06	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	mRNA Splicing
REAC:R-HSA-72203	9.39234395669e-06	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	Processing of Capped Intron-Containing Pre-mRNA
GO:0061574	8.45465618902e-05	0.25	RNPS1 SAP18 ACIN1	ASAP complex
CORUM:351	0.000209900402146	0.333333333333	RNPS1 CWC22 ACIN1 PRPF4B	Spliceosome
GO:0000377	0.00144841757832	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0000398	0.00144841757832	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	mRNA splicing, via spliceosome
GO:0000375	0.00158319444835	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	RNA splicing, via transesterification reactions
REAC:R-HSA-8953854	0.0020263217605	0.5	RNPS1 SNIP1 ACIN1 SAP18 PRPF4B CWC22	Metabolism of RNA

Showing 1 to 10 of 26 entries

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Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ACIN1	SAP18	1.0
RNPS1	GPATCH8	0.999	0.376
RNPS1	SAP18	0.999		structurally_consistent (dimer)
CWC22	EPB41L2	0.998	0.066
ACIN1	RNPS1	0.998	0.92	mutually_exclusive (P61326)
SETD2	SAP18	0.998
RNPS1	SNIP1	0.996	0.742	mutually_exclusive (P49760)
CWC22	RNPS1	0.996	0.318
ACIN1	NKTR	0.996	0.362
RNPS1	SETD2	0.994	0.126

Showing 1 to 10 of 65 entries

Related Complexes

Genename	Complexes
CWC22	huMAP3_00373.1 huMAP3_00489.1 huMAP3_07467.1 huMAP3_08365.1 huMAP3_08647.1 huMAP3_09637.1 huMAP3_09803.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_11077.1 huMAP3_11931.1 huMAP3_12350.1
SAP18	huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1
SETD2	huMAP3_02739.1 huMAP3_03484.1 huMAP3_05722.1 huMAP3_08365.1 huMAP3_08769.1 huMAP3_08851.1 huMAP3_09520.1 huMAP3_09637.1 huMAP3_09923.1 huMAP3_11073.1
RSBN1L	huMAP3_02403.1 huMAP3_02739.1 huMAP3_03128.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08715.1 huMAP3_08769.1 huMAP3_09607.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_11073.1
SNIP1	huMAP3_03772.1 huMAP3_06391.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07561.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08486.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10139.1 huMAP3_10564.1 huMAP3_11073.1
EPB41L2	huMAP3_00373.1 huMAP3_00489.1 huMAP3_00734.1 huMAP3_08365.1 huMAP3_08647.1 huMAP3_09637.1 huMAP3_09803.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_11077.1 huMAP3_11493.1
PRPF4B	huMAP3_05807.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_11073.1
NKTR	huMAP3_00489.1 huMAP3_01312.1 huMAP3_02739.1 huMAP3_04339.1 huMAP3_05069.1 huMAP3_05740.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_06799.1 huMAP3_07248.1 huMAP3_07309.1 huMAP3_07835.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08769.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10564.1 huMAP3_10789.1 huMAP3_11073.1 huMAP3_11261.1
ACIN1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_06219.1 huMAP3_07248.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
RNPS1	huMAP3_00373.1 huMAP3_00489.1 huMAP3_02739.1 huMAP3_03253.1 huMAP3_05722.1 huMAP3_06097.1 huMAP3_07248.1 huMAP3_07267.1 huMAP3_07291.1 huMAP3_08365.1 huMAP3_08745.1 huMAP3_08769.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
VANGL1	huMAP3_00489.1 huMAP3_06097.1 huMAP3_08365.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10250.1 huMAP3_12350.1
GPATCH8	huMAP3_02739.1 huMAP3_05319.1 huMAP3_05722.1 huMAP3_05740.1 huMAP3_07248.1 huMAP3_07737.1 huMAP3_08302.1 huMAP3_08365.1 huMAP3_08467.1 huMAP3_08769.1 huMAP3_09095.1 huMAP3_09226.1 huMAP3_09621.1 huMAP3_09637.1 huMAP3_09943.1 huMAP3_10789.1 huMAP3_11073.1