hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08368.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WBP2 | WW domain-binding protein 2 (WBP-2) | 5 | UniProt NCBI |
| EVL | Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) | 5 | UniProt NCBI |
| VASP | Vasodilator-stimulated phosphoprotein (VASP) | 5 | UniProt NCBI |
| ZYX | Zyxin (Zyxin-2) | 5 | UniProt NCBI |
| ENAH | Protein enabled homolog | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-202433 | 6.30285051125e-06 | 0.6 | EVL ENAH VASP | Generation of second messenger molecules |
| GO:0005522 | 0.000115261178119 | 0.6 | EVL ENAH VASP | profilin binding |
| REAC:R-HSA-202403 | 0.000595712868223 | 0.6 | EVL ENAH VASP | TCR signaling |
| KEGG:04015 | 0.000687014133415 | 0.6 | EVL ENAH VASP | Rap1 signaling pathway |
| REAC:R-HSA-376176 | 0.00464799867734 | 0.6 | EVL ENAH VASP | Signaling by ROBO receptors |
| GO:0017124 | 0.019918492568 | 0.6 | EVL ENAH VASP | SH3 domain binding |
| WP:WP185 | 0.020275205407 | 0.4 | VASP ZYX | Integrin mediated cell adhesion |
| CORUM:6731 | 0.0498708842806 | 0.2 | VASP | VASP-CXCR2 complex, CXCL8 stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| EVL | ENAH | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM Malo bioplex3_HCT116 gupta_WMM fraction | |
| VASP | ENAH | 1.0 | 0.052 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| EVL | VASP | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM Malo bioplex3_HCT116 fraction | |
| ENAH | ZYX | 0.996 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| VASP | ZYX | 0.97 | 0.424 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction |
| WBP2 | VASP | 0.957 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| EVL | WBP2 | 0.419 | bioplex_WMM bioplex3_WMM WMM_only | |
| WBP2 | ENAH | 0.204 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only |
| WBP2 | ZYX | 0.112 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| EVL | ZYX | 0.057 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM |
Related Complexes