hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08372.1
Complex Portal: CPX-17605
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GBP3 | Guanylate-binding protein 3 (EC 3.6.5.-) (GTP-binding protein 3) (GBP-3) (Guanine nucleotide-binding protein 3) | 5 | UniProt NCBI |
| GBP2 | Guanylate-binding protein 2 (EC 3.6.5.-) (GTP-binding protein 2) (GBP-2) (HuGBP-2) (Guanine nucleotide-binding protein 2) (Interferon-induced guanylate-binding protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04621 | 0.001720800216 | 1.0 | GBP2 GBP3 | NOD-like receptor signaling pathway |
| GO:0140639 | 0.00468200720083 | 1.0 | GBP2 GBP3 | positive regulation of pyroptosis |
| REAC:R-HSA-877300 | 0.00486997099357 | 1.0 | GBP2 GBP3 | Interferon gamma signaling |
| GO:0051715 | 0.00702301080125 | 1.0 | GBP2 GBP3 | cytolysis in another organism |
| GO:0019835 | 0.00983221512175 | 1.0 | GBP2 GBP3 | cytolysis |
| REAC:R-HSA-913531 | 0.0260158976762 | 1.0 | GBP2 GBP3 | Interferon Signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GBP3 | GBP2 | 0.999 |
mutually_exclusive (P32455)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| GBP3 | huMAP3_00791.1 huMAP3_08372.1 huMAP3_09442.1 huMAP3_12098.1 huMAP3_15160.1 |
| GBP2 | huMAP3_06824.1 huMAP3_08372.1 huMAP3_09442.1 huMAP3_12098.1 huMAP3_13465.1 |