hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08376.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC15A4 | Solute carrier family 15 member 4 (Peptide transporter 4) (Peptide/histidine transporter 1) (hPHT1) | 5 | UniProt NCBI |
| SLC12A7 | Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4) | 5 | UniProt NCBI |
| LGALS9 | Galectin-9 (Gal-9) (Ecalectin) (Tumor antigen HOM-HD-21) | 5 | UniProt NCBI |
| ATP2B4 | Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4) | 5 | UniProt NCBI |
| LGALS9C | Galectin-9C (Gal-9C) (Galectin-9-like protein B) | 5 | UniProt NCBI |
| SLC44A2 | Choline transporter-like protein 2 (Solute carrier family 44 member 2) | 5 | UniProt NCBI |
| SLC30A1 | Proton-coupled zinc antiporter SLC30A1 (Solute carrier family 30 member 1) (Zinc transporter 1) | 5 | UniProt NCBI |
| LUM | Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican) | 5 | UniProt NCBI |
| CLCN3 | H(+)/Cl(-) exchange transporter 3 (Chloride channel protein 3) (ClC-3) (Chloride transporter ClC-3) | 5 | UniProt NCBI |
| ABCC4 | ATP-binding cassette sub-family C member 4 (EC 7.6.2.-) (EC 7.6.2.2) (EC 7.6.2.3) (MRP/cMOAT-related ABC transporter) (Multi-specific organic anion transporter B) (MOAT-B) (Multidrug resistance-associated protein 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-382551 | 4.14784262889e-05 | 0.666666666667 | SLC30A1 ABCC4 SLC12A7 SLC15A4 CLCN3 SLC44A2 | Transport of small molecules |
| REAC:R-HSA-425407 | 0.000395821135224 | 0.444444444444 | SLC12A7 SLC15A4 SLC30A1 SLC44A2 | SLC-mediated transmembrane transport |
| GO:0022804 | 0.0132316433059 | 0.555555555556 | SLC12A7 CLCN3 ABCC4 SLC15A4 SLC30A1 | active transmembrane transporter activity |
| WP:WP3945 | 0.0300346853536 | 0.222222222222 | LGALS9C ABCC4 | TYROBP causal network in microglia |
| GO:0022857 | 0.0409845251376 | 0.666666666667 | SLC30A1 ABCC4 SLC12A7 SLC15A4 CLCN3 SLC44A2 | transmembrane transporter activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LGALS9 | LGALS9C | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS9 | SLC12A7 | 0.998 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS9C | SLC12A7 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS9 | ATP2B4 | 0.996 | 0.29 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ATP2B4 | LGALS9C | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LGALS9 | CLCN3 | 0.992 | 0.08 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LGALS9 | LUM | 0.991 | 0.132 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| LGALS9 | ABCC4 | 0.99 | 0.236 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| SLC44A2 | LGALS9 | 0.99 | 0.18 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| SLC30A1 | LGALS9 | 0.985 | 0.246 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| SLC15A4 | LGALS9 | 0.976 | 0.094 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| LGALS9C | ABCC4 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLC30A1 | SLC12A7 | 0.965 | 0.074 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| ATP2B4 | SLC12A7 | 0.961 | 0.036 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| SLC30A1 | ABCC4 | 0.952 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only |
| ATP2B4 | ABCC4 | 0.952 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC15A4 | SLC12A7 | 0.943 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC30A1 | CLCN3 | 0.941 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only |
| CLCN3 | ABCC4 | 0.935 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC12A7 | ABCC4 | 0.93 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only |
| ATP2B4 | CLCN3 | 0.921 | 0.13 | bioplex_WMM bioplex3_WMM WMM_only |
| CLCN3 | SLC12A7 | 0.911 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC15A4 | ABCC4 | 0.903 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC30A1 | ATP2B4 | 0.889 | 0.06 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| SLC15A4 | ATP2B4 | 0.863 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC30A1 | SLC15A4 | 0.81 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC44A2 | ABCC4 | 0.767 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC44A2 | SLC12A7 | 0.766 | 0.052 | bioplex3_WMM WMM_only |
| SLC44A2 | ATP2B4 | 0.587 | 0.106 | bioplex3_WMM WMM_only |
| SLC44A2 | SLC15A4 | 0.586 | 0.096 | bioplex3_WMM WMM_only |
| SLC15A4 | CLCN3 | 0.427 | 0.152 | bioplex_WMM bioplex3_WMM WMM_only |
| LUM | SLC12A7 | 0.395 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only |
| CLCN3 | LUM | 0.369 | 0.046 | bioplex_WMM bioplex3_WMM WMM_only |
| ATP2B4 | LUM | 0.25 | 0.208 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC44A2 | SLC30A1 | 0.249 | 0.026 | bioplex3_WMM WMM_only |
| SLC30A1 | LUM | 0.249 | 0.01 | bioplex3_WMM WMM_only |
| LUM | ABCC4 | 0.214 | 0.23 | bioplex3_WMM WMM_only |
| SLC44A2 | CLCN3 | 0.159 | 0.086 | bioplex3_WMM WMM_only |
| SLC44A2 | LUM | 0.046 | 0.048 | bioplex3_WMM WMM_only |
| SLC15A4 | LUM | 0.042 | 0.02 | bioplex3_WMM WMM_only |
Related Complexes