hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08403.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VKORC1 | Vitamin K epoxide reductase complex subunit 1 (EC 1.17.4.4) (Vitamin K1 2,3-epoxide reductase subunit 1) | 5 | UniProt NCBI |
| KTN1 | Kinectin (CG-1 antigen) (Kinesin receptor) | 5 | UniProt NCBI |
| RMND1 | Required for meiotic nuclear division protein 1 homolog | 5 | UniProt NCBI |
| CKAP4 | Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63) | 5 | UniProt NCBI |
| VDAC1 | Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) | 5 | UniProt NCBI |
| TMEM43 | Transmembrane protein 43 (Protein LUMA) | 5 | UniProt NCBI |
| MLEC | Malectin | 5 | UniProt NCBI |
| TMEM109 | Voltage-gated monoatomic cation channel TMEM109 (Mitsugumin-23) (Mg23) (Transmembrane protein 109) | 5 | UniProt NCBI |
| VDAC2 | Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2) | 5 | UniProt NCBI |
| CLCN7 | H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0540053 | 0.00631774157266 | 0.777777777778 | VDAC2 KTN1 CKAP4 RMND1 TMEM109 VKORC1 CLCN7 | stomach 1; glandular cells[High] |
| HPA:0461422 | 0.0180797357512 | 0.333333333333 | CKAP4 KTN1 VDAC2 | skin 1; eccrine glands[>=Medium] |
| HPA:0461421 | 0.0395221685132 | 0.333333333333 | CKAP4 KTN1 VDAC2 | skin 1; eccrine glands[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TMEM109 | TMEM43 | 0.999 | 0.192 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM boldt_WMM |
| VDAC2 | TMEM43 | 0.997 | 0.178 | hein_WMM bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only |
| VDAC1 | TMEM43 | 0.996 | 0.2 | hein_WMM bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only |
| VDAC1 | VDAC2 | 0.996 | 0.882 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM fraction boldt_WMM treiber_WMM |
| CKAP4 | TMEM43 | 0.995 | 0.372 | hein_WMM bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
| CKAP4 | MLEC | 0.992 | 0.25 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| CLCN7 | KTN1 | 0.992 | 0.078 | hein_WMM youn_WMM hein () gupta_WMM |
| VDAC1 | RMND1 | 0.991 | 0.162 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| RMND1 | TMEM109 | 0.991 | 0.048 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| CKAP4 | KTN1 | 0.991 | 0.292 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM boldt_WMM treiber_WMM |
| KTN1 | TMEM43 | 0.99 | 0.156 | hein_WMM bioplex_WMM bioplex3_WMM hein () |
| CKAP4 | CLCN7 | 0.989 | 0.08 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| VDAC1 | TMEM109 | 0.983 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM boldt hein () gupta_WMM boldt_WMM |
| VKORC1 | MLEC | 0.982 | hein_WMM bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| RMND1 | TMEM43 | 0.982 | 0.076 | hein_WMM bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
| VKORC1 | KTN1 | 0.982 | hein_WMM bioplex3_WMM hein () gupta_WMM | |
| CKAP4 | TMEM109 | 0.976 | 0.222 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| VDAC1 | MLEC | 0.975 | 0.226 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only |
| RMND1 | VDAC2 | 0.974 | 0.086 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| CKAP4 | VDAC1 | 0.968 | 0.292 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| VKORC1 | TMEM43 | 0.967 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| TMEM43 | MLEC | 0.951 | 0.316 | hein_WMM bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
| CLCN7 | TMEM43 | 0.939 | 0.04 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| CKAP4 | VDAC2 | 0.92 | 0.324 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM treiber_WMM WMM_only |
| TMEM109 | VDAC2 | 0.915 | 0.052 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () boldt_WMM |
| VDAC2 | KTN1 | 0.911 | 0.35 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| VDAC2 | MLEC | 0.875 | 0.23 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM treiber_WMM WMM_only |
| TMEM109 | KTN1 | 0.848 | 0.16 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| VDAC1 | KTN1 | 0.781 | 0.488 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| VKORC1 | CLCN7 | 0.774 | hein_WMM WMM_only | |
| CLCN7 | MLEC | 0.764 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| VKORC1 | VDAC2 | 0.756 | hein_WMM bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| KTN1 | MLEC | 0.722 | 0.294 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| CLCN7 | VDAC2 | 0.657 | 0.136 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| CKAP4 | VKORC1 | 0.632 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TMEM109 | CLCN7 | 0.621 | 0.062 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| TMEM109 | VKORC1 | 0.444 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TMEM109 | MLEC | 0.362 | 0.158 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| VDAC1 | CLCN7 | 0.325 | 0.17 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| VDAC1 | VKORC1 | 0.26 | hein_WMM bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| RMND1 | KTN1 | 0.245 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
| RMND1 | MLEC | 0.066 | 0.152 | bioplex_WMM bioplex3_WMM WMM_only |
| CKAP4 | RMND1 | 0.064 | 0.088 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
| RMND1 | CLCN7 | 0.021 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes