hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08420.1
Complex Portal: CPX-22950
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GUF1 | Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase) | 4 | UniProt NCBI |
| AMACR | Alpha-methylacyl-CoA racemase (EC 5.1.99.4) (2-methylacyl-CoA racemase) | 5 | UniProt NCBI |
| COQ6 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial (EC 1.14.13.-) (Coenzyme Q10 monooxygenase 6) | 5 | UniProt NCBI |
| CPT2 | Carnitine O-palmitoyltransferase 2, mitochondrial (EC 2.3.1.21) (Carnitine palmitoyltransferase II) (CPT II) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010964 | 0.00400802433742 | 0.5 | AMACR CPT2 | Abnormal circulating long-chain fatty-acid concentration |
| HP:0001298 | 0.0158129816731 | 0.75 | GUF1 CPT2 AMACR | Encephalopathy |
| HP:0003201 | 0.0246976114972 | 0.5 | AMACR CPT2 | Rhabdomyolysis |
| HP:0010996 | 0.034474601612 | 0.5 | AMACR CPT2 | Abnormal circulating monocarboxylic acid concentration |
| HP:0004359 | 0.040788355352 | 0.5 | AMACR CPT2 | Abnormal circulating fatty-acid concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GUF1 | AMACR | 0.99 | 0.124 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COQ6 | AMACR | 0.979 | 0.07 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| AMACR | CPT2 | 0.97 | 0.206 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| GUF1 | COQ6 | 0.76 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| COQ6 | CPT2 | 0.655 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only | |
| GUF1 | CPT2 | 0.513 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes