hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08444.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ST8SIA4 | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV) | 5 | UniProt NCBI |
| CACHD1 | VWFA and cache domain-containing protein 1 (Cache domain-containing protein 1) | 4 | UniProt NCBI |
| ADAMTS2 | A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAM-TS 2) (ADAM-TS2) (ADAMTS-2) (EC 3.4.24.14) (Procollagen I N-proteinase) (PC I-NP) (Procollagen I/II amino propeptide-processing enzyme) (Procollagen N-endopeptidase) (pNPI) | 5 | UniProt NCBI |
| RNASEL | 2-5A-dependent ribonuclease (2-5A-dependent RNase) (EC 3.1.26.-) (Ribonuclease 4) (Ribonuclease L) (RNase L) | 5 | UniProt NCBI |
| GLG1 | Golgi apparatus protein 1 (CFR-1) (Cysteine-rich fibroblast growth factor receptor) (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160) | 5 | UniProt NCBI |
| ST8SIA2 | Alpha-2,8-sialyltransferase 8B (EC 2.4.3.-) (Sialyltransferase 8B) (SIAT8-B) (Sialyltransferase St8Sia II) (ST8SiaII) (Sialyltransferase X) (STX) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-419037 | 0.00902151290218 | 0.333333333333 | ST8SIA4 ST8SIA2 | NCAM1 interactions |
| REAC:R-HSA-4085001 | 0.0111743831709 | 0.333333333333 | ST8SIA4 ST8SIA2 | Sialic acid metabolism |
| REAC:R-HSA-375165 | 0.0220691409046 | 0.333333333333 | ST8SIA4 ST8SIA2 | NCAM signaling for neurite out-growth |
| REAC:R-HSA-446219 | 0.0422459670228 | 0.333333333333 | ST8SIA4 ST8SIA2 | Synthesis of substrates in N-glycan biosythesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ST8SIA2 | ST8SIA4 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RNASEL | ST8SIA4 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ADAMTS2 | ST8SIA4 | 0.967 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GLG1 | ST8SIA4 | 0.965 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ADAMTS2 | GLG1 | 0.951 | bioplex_WMM bioplex3_WMM WMM_only | |
| CACHD1 | ST8SIA4 | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| GLG1 | CACHD1 | 0.575 | 0.114 | bioplex_WMM bioplex3_WMM WMM_only |
| ADAMTS2 | CACHD1 | 0.203 | bioplex_WMM bioplex3_WMM WMM_only | |
| RNASEL | CACHD1 | 0.106 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only |
| ADAMTS2 | RNASEL | 0.033 | bioplex_WMM bioplex3_WMM WMM_only | |
| GLG1 | RNASEL | 0.016 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes