hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08448.1

Complex Portal: CPX-15122

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
FAR1	Fatty acyl-CoA reductase 1 (EC 1.2.1.84) (Male sterility domain-containing protein 2)	5	UniProt NCBI
YME1L1	ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)	5	UniProt NCBI
SLC35E1	Solute carrier family 35 member E1	3	UniProt NCBI
SLC38A5	Sodium-coupled neutral amino acid transporter 5 (Solute carrier family 38 member 5) (System N transporter 2)	5	UniProt NCBI
QSOX2	Sulfhydryl oxidase 2 (EC 1.8.3.2) (Neuroblastoma-derived sulfhydryl oxidase) (Quiescin Q6-like protein 1)	5	UniProt NCBI
KDELR2	ER lumen protein-retaining receptor 2 (ERD2-like protein 1) (ELP-1) (KDEL endoplasmic reticulum protein retention receptor 2) (KDEL receptor 2)	5	UniProt NCBI
SLC39A7	Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7)	5	UniProt NCBI
NDUFA11	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (Complex I-B14.7) (CI-B14.7) (NADH-ubiquinone oxidoreductase subunit B14.7)	5	UniProt NCBI
RHBDD2	Rhomboid domain-containing protein 2	5	UniProt NCBI
SEC61A1	Protein transport protein Sec61 subunit alpha isoform 1 (Sec61 alpha-1)	5	UniProt NCBI
SLC7A11	Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)	5	UniProt NCBI
ACSL4	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 4) (LACS 4)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04216	0.0163080582055	0.181818181818	SLC7A11 ACSL4	Ferroptosis
REAC:R-HSA-352230	0.0305690780225	0.181818181818	SLC7A11 SLC38A5	Amino acid transport across the plasma membrane

Edges

Protein 1	Protein 2	Score	ProteomeHD
SLC35E1	FAR1	0.993	0.036
SLC35E1	NDUFA11	0.992	0.024
SLC35E1	SEC61A1	0.987	0.096
NDUFA11	KDELR2	0.984	0.086
SLC7A11	FAR1	0.984	0.194
ACSL4	KDELR2	0.983	0.068
SLC7A11	SLC35E1	0.983	0.07
SLC35E1	SLC38A5	0.982	0.022
FAR1	QSOX2	0.982	0.146
SLC35E1	SLC39A7	0.978	0.116
SLC35E1	ACSL4	0.975	0.048
SLC35E1	YME1L1	0.974	0.042
SLC35E1	RHBDD2	0.974	0.288
YME1L1	ACSL4	0.969	0.076
YME1L1	FAR1	0.969	0.054
FAR1	KDELR2	0.964	0.134
FAR1	ACSL4	0.962	0.094
SLC7A11	RHBDD2	0.961	0.098
SLC39A7	SEC61A1	0.952	0.126
SEC61A1	RHBDD2	0.946	0.102
SLC39A7	QSOX2	0.944	0.03
SLC35E1	QSOX2	0.94	0.034
NDUFA11	RHBDD2	0.932	0.05
SLC7A11	SEC61A1	0.928	0.168
SEC61A1	FAR1	0.928	0.078
ACSL4	RHBDD2	0.914	0.056
SLC35E1	KDELR2	0.911	0.11
FAR1	RHBDD2	0.89	0.07
SEC61A1	KDELR2	0.875	0.168
SLC7A11	QSOX2	0.861	0.094
QSOX2	RHBDD2	0.836	0.078
SEC61A1	QSOX2	0.819	0.04
KDELR2	RHBDD2	0.798	0.132
SLC38A5	SEC61A1	0.75	0.1
SLC7A11	NDUFA11	0.72	0.126
SLC38A5	YME1L1	0.656	0.098
YME1L1	QSOX2	0.654	0.07
FAR1	NDUFA11	0.622	0.03
SLC7A11	ACSL4	0.62	0.152
SLC39A7	YME1L1	0.579	0.03
ACSL4	NDUFA11	0.553	0.022
SEC61A1	ACSL4	0.494	0.086
SLC7A11	KDELR2	0.49	0.046
SLC38A5	FAR1	0.473	0.146
SLC7A11	YME1L1	0.409	0.034
YME1L1	KDELR2	0.391	0.064
SLC38A5	ACSL4	0.374	0.152
SLC38A5	KDELR2	0.374	0.084
YME1L1	NDUFA11	0.344	0.022
SLC38A5	RHBDD2	0.335	0.084
SLC39A7	FAR1	0.319	0.034
ACSL4	QSOX2	0.298	0.062
SLC39A7	SLC38A5	0.229	0.078
SEC61A1	NDUFA11	0.209	0.048
SLC39A7	NDUFA11	0.156	0.05
NDUFA11	QSOX2	0.156	0.008
SLC38A5	NDUFA11	0.142	0.012
SLC39A7	KDELR2	0.108	0.372
KDELR2	QSOX2	0.107	0.12
SLC7A11	SLC39A7	0.089	0.038
SLC38A5	QSOX2	0.076	0.05
SLC7A11	SLC38A5	0.072	0.08
YME1L1	SEC61A1	0.051	0.19
SLC39A7	RHBDD2	0.049	0.11
SLC39A7	ACSL4	0.045	0.008
YME1L1	RHBDD2	0.038	0.048

Related Complexes

Genename	Complexes
FAR1	huMAP3_05784.1 huMAP3_08448.1 huMAP3_09904.1
YME1L1	huMAP3_02214.1 huMAP3_08448.1 huMAP3_09904.1 huMAP3_15030.1
SLC35E1	huMAP3_00678.1 huMAP3_05784.1 huMAP3_07365.1 huMAP3_08448.1 huMAP3_09904.1
SLC38A5	huMAP3_01649.1 huMAP3_02027.1 huMAP3_05783.1 huMAP3_05784.1 huMAP3_05797.1 huMAP3_08448.1 huMAP3_09904.1 huMAP3_10245.1 huMAP3_10473.1
QSOX2	huMAP3_08448.1 huMAP3_09592.1
KDELR2	huMAP3_07365.1 huMAP3_08448.1 huMAP3_09904.1
SLC39A7	huMAP3_00678.1 huMAP3_03704.1 huMAP3_05784.1 huMAP3_05797.1 huMAP3_07977.1 huMAP3_08448.1 huMAP3_09691.1 huMAP3_09904.1 huMAP3_10473.1 huMAP3_11421.1
NDUFA11	huMAP3_06885.1 huMAP3_07365.1 huMAP3_08448.1 huMAP3_09904.1
RHBDD2	huMAP3_08448.1 huMAP3_09904.1
SEC61A1	huMAP3_05784.1 huMAP3_06247.1 huMAP3_07170.1 huMAP3_08448.1 huMAP3_09592.1
SLC7A11	huMAP3_00678.1 huMAP3_05784.1 huMAP3_07365.1 huMAP3_08448.1 huMAP3_09904.1
ACSL4	huMAP3_06247.1 huMAP3_06791.1 huMAP3_08448.1 huMAP3_09592.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08448.1

Complex Portal: CPX-15122