hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08455.1
Complex Portal: CPX-17004
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNIP4 | Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) | 5 | UniProt NCBI |
| KCNIP2 | Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2) | 5 | UniProt NCBI |
| APMAP | Adipocyte plasma membrane-associated protein (Protein BSCv) | 5 | UniProt NCBI |
| KCNIP1 | Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) | 5 | UniProt NCBI |
| KCNIP3 | Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5576894 | 2.13564856385e-12 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | Phase 1 - inactivation of fast Na+ channels |
| REAC:R-HSA-5576891 | 8.61057377169e-07 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | Cardiac conduction |
| GO:0015459 | 5.37501604002e-06 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | potassium channel regulator activity |
| REAC:R-HSA-397014 | 8.58505749822e-06 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | Muscle contraction |
| GO:1901379 | 3.84216218146e-05 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of potassium ion transmembrane transport |
| GO:0008076 | 4.14930734417e-05 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | voltage-gated potassium channel complex |
| GO:0043266 | 5.56532631373e-05 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of potassium ion transport |
| GO:0034705 | 6.84426164966e-05 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | potassium channel complex |
| GO:0099106 | 0.00043484599868 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | ion channel regulator activity |
| GO:0016247 | 0.000534309588813 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | channel regulator activity |
| GO:0141108 | 0.000534309588813 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | transporter regulator activity |
| GO:0071805 | 0.00118663084114 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | potassium ion transmembrane transport |
| GO:0034703 | 0.00148410028721 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | cation channel complex |
| GO:0006813 | 0.00157850838896 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | potassium ion transport |
| GO:0034702 | 0.00407551040215 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | monoatomic ion channel complex |
| GO:1904062 | 0.00563530898302 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of monoatomic cation transmembrane transport |
| GO:0034765 | 0.00825090824596 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of monoatomic ion transmembrane transport |
| GO:0010959 | 0.0130363720333 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of metal ion transport |
| GO:1902495 | 0.0187071120569 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | transmembrane transporter complex |
| GO:0043269 | 0.0233977310013 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of monoatomic ion transport |
| GO:1990351 | 0.025656507175 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | transporter complex |
| GO:0034762 | 0.0302165890257 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | regulation of transmembrane transport |
| GO:0005509 | 0.0358551890782 | 0.8 | KCNIP4 KCNIP2 KCNIP3 KCNIP1 | calcium ion binding |
| CORUM:6650 | 0.0498708842806 | 0.2 | KCNIP4 | KCND3-KCNIP4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNIP2 | KCNIP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNIP4 | KCNIP2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNIP4 | KCNIP1 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KCNIP4 | KCNIP3 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| KCNIP4 | APMAP | 0.993 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNIP1 | APMAP | 0.835 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNIP3 | KCNIP1 | 0.543 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNIP2 | KCNIP3 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNIP3 | APMAP | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KCNIP2 | APMAP | 0.098 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes