hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08465.1

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
TARBP2	RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)	5	UniProt NCBI
ZNF770	Zinc finger protein 770	3	UniProt NCBI
APOBEC3C	DNA dC->dU-editing enzyme APOBEC-3C (A3C) (EC 3.5.4.38) (APOBEC1-like) (Phorbolin I)	5	UniProt NCBI
C8orf33	UPF0488 protein C8orf33	5	UniProt NCBI
GRWD1	Glutamate-rich WD repeat-containing protein 1	5	UniProt NCBI
NOL8	Nucleolar protein 8 (Nucleolar protein Nop132)	5	UniProt NCBI
WDR36	WD repeat-containing protein 36 (T-cell activation WD repeat-containing protein) (TA-WDRP)	5	UniProt NCBI
URB2	Unhealthy ribosome biogenesis protein 2 homolog	3	UniProt NCBI
WDR89	WD repeat-containing protein 89	2	UniProt NCBI
RPL3	Large ribosomal subunit protein uL3 (60S ribosomal protein L3) (HIV-1 TAR RNA-binding protein B) (TARBP-B)	5	UniProt NCBI
ZNF16	Zinc finger protein 16 (Zinc finger protein KOX9)	5	UniProt NCBI
XRN1	5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)	5	UniProt NCBI
DDX52	Probable ATP-dependent RNA helicase DDX52 (EC 3.6.4.13) (ATP-dependent RNA helicase ROK1-like) (DEAD box protein 52)	5	UniProt NCBI
ZBTB41	Zinc finger and BTB domain-containing protein 41	3	UniProt NCBI
RPL10A	Large ribosomal subunit protein uL1 (60S ribosomal protein L10a) (CSA-19) (Neural precursor cell expressed developmentally down-regulated protein 6) (NEDD-6)	5	UniProt NCBI
RPL15	Large ribosomal subunit protein eL15 (60S ribosomal protein L15)	5	UniProt NCBI
RRP15	RRP15-like protein (Ribosomal RNA-processing protein 15)	3	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:308	0.000475873773807	0.2	RPL15 RPL3 RPL10A	60S ribosomal subunit, cytoplasmic
CORUM:306	0.00252936451858	0.2	RPL15 RPL3 RPL10A	Ribosome, cytoplasmic
GO:0022613	0.00253039690998	0.466666666667	NOL8 URB2 RRP15 TARBP2 RPL10A DDX52 GRWD1	ribonucleoprotein complex biogenesis
CORUM:3055	0.00504754432189	0.2	RPL15 RPL3 RPL10A	Nop56p-associated pre-rRNA complex
GO:0042254	0.00570113122599	0.4	NOL8 URB2 DDX52 RPL10A RRP15 GRWD1	ribosome biogenesis
REAC:R-HSA-6791226	0.00817918845653	0.266666666667	DDX52 RPL15 RPL3 RPL10A	Major pathway of rRNA processing in the nucleolus and cytosol
WP:WP477	0.00978158342006	0.2	RPL15 RPL3 RPL10A	Cytoplasmic ribosomal proteins
CORUM:5380	0.00991081017598	0.133333333333	RPL15 RPL10A	TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle)
REAC:R-HSA-8868773	0.0101105523609	0.266666666667	DDX52 RPL15 RPL3 RPL10A	rRNA processing in the nucleus and cytosol
REAC:R-HSA-8953854	0.0107143533133	0.4	APOBEC3C RPL15 RPL10A DDX52 XRN1 RPL3	Metabolism of RNA
REAC:R-HSA-72312	0.0123578325655	0.266666666667	DDX52 RPL15 RPL3 RPL10A	rRNA processing
KEGG:03010	0.0164970695273	0.2	RPL15 RPL3 RPL10A	Ribosome
REAC:R-HSA-192823	0.0272710008453	0.2	RPL15 RPL3 RPL10A	Viral mRNA Translation
REAC:R-HSA-156902	0.0272710008453	0.2	RPL15 RPL3 RPL10A	Peptide chain elongation
REAC:R-HSA-2408557	0.030134983839	0.2	RPL15 RPL3 RPL10A	Selenocysteine synthesis
REAC:R-HSA-72764	0.030134983839	0.2	RPL15 RPL3 RPL10A	Eukaryotic Translation Termination
REAC:R-HSA-156842	0.0311315607877	0.2	RPL15 RPL3 RPL10A	Eukaryotic Translation Elongation
REAC:R-HSA-975956	0.0331888349265	0.2	RPL15 RPL3 RPL10A	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
REAC:R-HSA-9633012	0.0398884538309	0.2	RPL15 RPL3 RPL10A	Response of EIF2AK4 (GCN2) to amino acid deficiency
REAC:R-HSA-72689	0.0398884538309	0.2	RPL15 RPL3 RPL10A	Formation of a pool of free 40S subunits

Edges

Protein 1	Protein 2	Score	ProteomeHD
RPL3	RPL15	1.0	1.0
RPL3	RPL10A	0.999	1.0
RPL10A	RPL15	0.999	1.0
RPL3	RRP15	0.999	0.326
RPL15	RRP15	0.998	0.628
RPL3	APOBEC3C	0.998	0.09
RPL3	URB2	0.997	0.302
GRWD1	RPL3	0.997	0.576
WDR89	NOL8	0.997	0.186
C8orf33	RPL3	0.996	0.212
NOL8	URB2	0.996	0.516
NOL8	RPL3	0.996	0.28
NOL8	RPL10A	0.995	0.18
RPL10A	RRP15	0.994	0.444
C8orf33	RRP15	0.994	0.186
APOBEC3C	RPL15	0.993	0.114
C8orf33	RPL10A	0.993	0.22
WDR36	RRP15	0.991	0.668
NOL8	RPL15	0.988	0.426
C8orf33	WDR36	0.988	0.096
ZBTB41	RPL3	0.987
APOBEC3C	RPL10A	0.987	0.04
TARBP2	RPL15	0.987
WDR89	RPL10A	0.987	0.094
WDR36	RPL15	0.985	0.94
URB2	RPL10A	0.982	0.232
WDR36	URB2	0.981	0.634
WDR89	RPL3	0.981	0.134
APOBEC3C	RRP15	0.977	0.012
GRWD1	C8orf33	0.977	0.404
WDR89	APOBEC3C	0.974	0.04
RPL3	ZNF770	0.971	0.452
ZNF16	RPL3	0.97
DDX52	RPL3	0.97	0.642
TARBP2	RPL3	0.968
URB2	RPL15	0.967	0.346
WDR36	RPL3	0.966	0.87
TARBP2	WDR36	0.962
WDR36	RPL10A	0.961	0.93
C8orf33	RPL15	0.959	0.394
XRN1	RPL3	0.953	0.272
ZNF770	RPL10A	0.953	0.35
C8orf33	URB2	0.949	0.054
APOBEC3C	URB2	0.949	0.088
NOL8	RRP15	0.947	0.084
GRWD1	RPL15	0.922	0.502
ZNF770	RPL15	0.917	0.364
ZNF770	RRP15	0.917	0.112
WDR89	URB2	0.897	0.11
NOL8	APOBEC3C	0.893	0.028
C8orf33	APOBEC3C	0.891	0.028
NOL8	C8orf33	0.89	0.024
DDX52	RRP15	0.888	0.622
WDR36	ZNF770	0.882	0.136
TARBP2	RPL10A	0.864
C8orf33	ZNF770	0.862	0.114
TARBP2	ZNF770	0.857
NOL8	ZBTB41	0.839
DDX52	RPL15	0.839	0.852
URB2	RRP15	0.832	0.492
NOL8	ZNF770	0.821	0.094
WDR89	C8orf33	0.803	0.036
ZBTB41	C8orf33	0.796
ZBTB41	URB2	0.794
WDR89	XRN1	0.787	0.056
TARBP2	APOBEC3C	0.78
ZNF16	WDR36	0.776
ZBTB41	APOBEC3C	0.772
DDX52	C8orf33	0.747	0.102
NOL8	ZNF16	0.744
DDX52	RPL10A	0.734	0.4168
DDX52	APOBEC3C	0.733	0.074
ZNF770	URB2	0.729	0.08
TARBP2	RRP15	0.722
DDX52	ZBTB41	0.714
TARBP2	C8orf33	0.713
ZBTB41	ZNF16	0.71
ZNF770	APOBEC3C	0.708	0.056
WDR89	ZNF770	0.705	0.15
TARBP2	ZBTB41	0.7
ZNF16	URB2	0.7
DDX52	ZNF770	0.692	0.122
XRN1	C8orf33	0.67	0.022
TARBP2	NOL8	0.664
ZNF16	RPL15	0.627
WDR36	APOBEC3C	0.615	0.086
XRN1	URB2	0.609	0.062
TARBP2	ZNF16	0.603
ZNF16	RPL10A	0.587
WDR89	GRWD1	0.57	0.058
ZBTB41	ZNF770	0.565
ZNF16	APOBEC3C	0.562
ZBTB41	GRWD1	0.561
ZNF16	ZNF770	0.548
ZBTB41	RPL10A	0.545
ZBTB41	RRP15	0.543
ZBTB41	RPL15	0.514
ZNF16	RRP15	0.479
XRN1	ZNF770	0.44	0.102
TARBP2	URB2	0.42
XRN1	RPL15	0.411	0.224
DDX52	ZNF16	0.411
GRWD1	APOBEC3C	0.384	0.0442909090909
DDX52	URB2	0.378	0.32
NOL8	WDR36	0.378	0.276
XRN1	ZBTB41	0.372
ZNF16	C8orf33	0.371
DDX52	NOL8	0.366	0.066
XRN1	TARBP2	0.344
WDR89	DDX52	0.303	0.082
XRN1	ZNF16	0.284
NOL8	GRWD1	0.283	0.058
WDR89	RRP15	0.26	0.064
WDR89	TARBP2	0.242
WDR89	ZBTB41	0.214
GRWD1	ZNF16	0.204
XRN1	RRP15	0.198	0.012
XRN1	NOL8	0.191	0.024
XRN1	RPL10A	0.18	0.218
GRWD1	URB2	0.149	0.16
XRN1	APOBEC3C	0.109	0.044
WDR89	RPL15	0.098	0.148
DDX52	TARBP2	0.093
WDR89	ZNF16	0.087
WDR89	WDR36	0.087	0.062
GRWD1	RPL10A	0.084	0.594
TARBP2	GRWD1	0.066
ZBTB41	WDR36	0.063
XRN1	GRWD1	0.048	0.042
GRWD1	ZNF770	0.045	0.076
DDX52	GRWD1	0.024	0.372
GRWD1	RRP15	0.021	0.452
XRN1	DDX52	0.016	0.018
XRN1	WDR36	0.016	0.044
DDX52	WDR36	0.016	0.832
GRWD1	WDR36	0.008	0.266

Related Complexes

Genename	Complexes
TARBP2	huMAP3_01680.1 huMAP3_07613.1 huMAP3_08465.1
ZNF770	huMAP3_06336.1 huMAP3_08465.1
APOBEC3C	huMAP3_07224.1 huMAP3_08465.1 huMAP3_09610.1 huMAP3_10431.1
C8orf33	huMAP3_03966.1 huMAP3_08465.1
GRWD1	huMAP3_02406.1 huMAP3_08465.1 huMAP3_10062.1 huMAP3_12390.1
NOL8	huMAP3_01862.1 huMAP3_08465.1 huMAP3_09131.1 huMAP3_10427.1
WDR36	huMAP3_03966.1 huMAP3_08465.1
URB2	huMAP3_08465.1
WDR89	huMAP3_00874.1 huMAP3_08465.1 huMAP3_09131.1 huMAP3_09610.1 huMAP3_10427.1 huMAP3_10836.1 huMAP3_12689.1 huMAP3_15310.1
RPL3	huMAP3_03966.1 huMAP3_08465.1
ZNF16	huMAP3_02789.1 huMAP3_03966.1 huMAP3_08237.1 huMAP3_08465.1 huMAP3_10445.1
XRN1	huMAP3_01210.1 huMAP3_06122.1 huMAP3_06400.1 huMAP3_08465.1 huMAP3_09148.1 huMAP3_09378.1 huMAP3_09667.1
DDX52	huMAP3_01512.1 huMAP3_01944.1 huMAP3_04077.1 huMAP3_06378.1 huMAP3_08465.1 huMAP3_09055.1
ZBTB41	huMAP3_02371.1 huMAP3_02503.1 huMAP3_02657.1 huMAP3_06145.1 huMAP3_08465.1 huMAP3_10045.1 huMAP3_10814.1
RPL10A	huMAP3_08465.1
RPL15	huMAP3_08465.1
RRP15	huMAP3_08465.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08465.1