hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08487.1

Complex Portal: CPX-22594

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
POLR3B	DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)	5	UniProt NCBI
RRN3	RNA polymerase I-specific transcription initiation factor RRN3 (Transcription initiation factor IA) (TIF-IA)	5	UniProt NCBI
CRCP	DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9) (Calcitonin gene-related peptide-receptor component protein) (CGRP-RCP) (CGRP-receptor component protein) (CGRPRCP) (HsC17)	5	UniProt NCBI
POLR2F	DNA-directed RNA polymerases I, II, and III subunit RPABC2 (RNA polymerases I, II, and III subunit ABC2) (DNA-directed RNA polymerase II subunit F) (DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide) (RPABC14.4) (RPB14.4) (RPB6 homolog) (RPC15)	5	UniProt NCBI
POLR3H	DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9)	5	UniProt NCBI
PIH1D1	PIH1 domain-containing protein 1 (Nucleolar protein 17 homolog)	5	UniProt NCBI
POLR2L	DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)	5	UniProt NCBI
POLR1C	DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)	5	UniProt NCBI
POLR3D	DNA-directed RNA polymerase III subunit RPC4 (RNA polymerase III subunit C4) (DNA-directed RNA polymerase III subunit D) (Protein BN51) (RNA polymerase III 47 kDa subunit) (RPC53 homolog)	5	UniProt NCBI
PFDN6	Prefoldin subunit 6 (Protein Ke2)	5	UniProt NCBI
GPN3	GPN-loop GTPase 3 (ATP-binding domain 1 family member C)	4	UniProt NCBI
UXT	Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein)	5	UniProt NCBI
POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (DNA-directed RNA polymerase II subunit H) (DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide) (RPB17) (RPB8 homolog) (hRPB8)	5	UniProt NCBI
POLR1G	DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)	5	UniProt NCBI
POLR3A	DNA-directed RNA polymerase III subunit RPC1 (RNA polymerase III subunit C1) (EC 2.7.7.6) (DNA-directed RNA polymerase III largest subunit) (DNA-directed RNA polymerase III subunit A) (RNA polymerase III 155 kDa subunit) (RPC155) (RNA polymerase III subunit C160)	5	UniProt NCBI
POLR2K	DNA-directed RNA polymerases I, II, and III subunit RPABC4 (RNA polymerases I, II, and III subunit ABC4) (ABC10-alpha) (DNA-directed RNA polymerase II subunit K) (RNA polymerase II 7.0 kDa subunit) (RPB7.0) (RPB10alpha)	5	UniProt NCBI
POLR1B	DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)	5	UniProt NCBI
POLR1A	DNA-directed RNA polymerase I subunit RPA1 (RNA polymerase I subunit A1) (EC 2.7.7.6) (A190) (DNA-directed RNA polymerase I largest subunit) (DNA-directed RNA polymerase I subunit A) (RNA polymerase I 194 kDa subunit) (RPA194)	5	UniProt NCBI
GPN1	GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1)	5	UniProt NCBI
POLR2A	DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)	5	UniProt NCBI
POLR3GL	DNA-directed RNA polymerase III subunit RPC7-like (RNA polymerase III subunit C7-like) (DNA-directed RNA polymerase III subunit G-like) (RNA polymerase III 32 kDa beta subunit) (RPC32-beta)	5	UniProt NCBI
POLR1H	DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) (Zinc ribbon domain-containing protein 1)	5	UniProt NCBI
POLR3K	DNA-directed RNA polymerase III subunit RPC10 (RNA polymerase III subunit C10) (DNA-directed RNA polymerase III subunit K) (RNA polymerase III 12.5 kDa subunit) (RPC12.5) (RNA polymerase III subunit C11) (HsC11p) (RPC11) (hRPC11)	5	UniProt NCBI
POLR2E	DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)	5	UniProt NCBI
RPAP1	RNA polymerase II-associated protein 1	5	UniProt NCBI
GPN2	GPN-loop GTPase 2 (ATP-binding domain 1 family member B)	3	UniProt NCBI
POLR1E	DNA-directed RNA polymerase I subunit RPA49 (RNA polymerase I subunit A49) (DNA-directed RNA polymerase I subunit E) (RNA polymerase I-associated factor 1) (RNA polymerase I-associated factor 53)	5	UniProt NCBI
DNAAF10	Dynein axonemal assembly factor 10 (WD repeat-containing protein 92) (WD repeat-containing protein Monad)	4	UniProt NCBI
POLR3E	DNA-directed RNA polymerase III subunit RPC5 (RNA polymerase III subunit C5) (DNA-directed RNA polymerase III 80 kDa polypeptide)	5	UniProt NCBI
POLR3F	DNA-directed RNA polymerase III subunit RPC6 (RNA polymerase III subunit C6) (DNA-directed RNA polymerase III subunit F) (RNA polymerase III 39 kDa subunit) (RPC39)	5	UniProt NCBI
URI1	Unconventional prefoldin RPB5 interactor 1 (Protein NNX3) (Protein phosphatase 1 regulatory subunit 19) (RNA polymerase II subunit 5-mediating protein) (RPB5-mediating protein)	5	UniProt NCBI
POLR3G	DNA-directed RNA polymerase III subunit RPC7 (RNA polymerase III subunit C7) (DNA-directed RNA polymerase III subunit G) (RNA polymerase III 32 kDa apha subunit) (RPC32-alpha) (RNA polymerase III 32 kDa subunit) (RPC32)	5	UniProt NCBI
POLR3C	DNA-directed RNA polymerase III subunit RPC3 (RNA polymerase III subunit C3) (DNA-directed RNA polymerase III subunit C) (RNA polymerase III 62 kDa subunit) (RPC62)	5	UniProt NCBI
POLR1D	DNA-directed RNA polymerases I and III subunit RPAC2 (RNA polymerases I and III subunit AC2) (AC19) (DNA-directed RNA polymerase I subunit D) (RNA polymerase I 16 kDa subunit) (RPA16) (RPC16) (hRPA19)	5	UniProt NCBI
POLR1F	DNA-directed RNA polymerase I subunit RPA43 (DNA-directed RNA polymerase I subunit F) (Twist neighbor protein)	4	UniProt NCBI
PDRG1	p53 and DNA damage-regulated protein 1	4	UniProt NCBI
RPAP3	RNA polymerase II-associated protein 3	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:03020	6.04173138686e-59	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	RNA polymerase
REAC:R-HSA-73780	1.99497090975e-47	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Chain Elongation
GO:0005666	3.1720037465e-45	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA polymerase III complex
REAC:R-HSA-73980	6.67375341967e-43	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription Termination
REAC:R-HSA-76061	3.08767766657e-41	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription Initiation From Type 1 Promoter
REAC:R-HSA-76066	3.08767766657e-41	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription Initiation From Type 2 Promoter
GO:0055029	3.36068373627e-41	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	nuclear DNA-directed RNA polymerase complex
GO:0000428	4.52602516603e-41	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	DNA-directed RNA polymerase complex
REAC:R-HSA-76071	9.25220630542e-41	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription Initiation From Type 3 Promoter
GO:0030880	1.08172539133e-40	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	RNA polymerase complex
GO:0003899	4.11426753876e-38	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	DNA-directed 5'-3' RNA polymerase activity
REAC:R-HSA-76046	4.31533343109e-38	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription Initiation
GO:0034062	2.70534020709e-37	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	5'-3' RNA polymerase activity
GO:0097747	2.70534020709e-37	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	RNA polymerase activity
REAC:R-HSA-74158	1.21386230304e-36	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Transcription
REAC:R-HSA-749476	1.21386230304e-36	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	RNA Polymerase III Abortive And Retractive Initiation
REAC:R-HSA-1834949	1.23126265106e-32	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	Cytosolic sensors of pathogen-associated DNA
GO:0005736	5.21128172646e-31	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	RNA polymerase I complex
WP:WP4655	1.11163327991e-29	0.472222222222	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	Cytosolic DNA sensing pathway
KEGG:04623	2.36966683264e-29	0.472222222222	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	Cytosolic DNA-sensing pathway
GO:0061695	7.88843114691e-29	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	transferase complex, transferring phosphorus-containing groups
GO:0016779	5.94185057891e-26	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	nucleotidyltransferase activity
GO:0140535	1.04457453886e-25	0.805555555556	POLR2H POLR3E CRCP POLR1E POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3GL PDRG1 POLR1D POLR1G POLR3G POLR3F URI1 POLR1F RPAP3 POLR2E POLR2F POLR3B POLR3K PFDN6 POLR3D POLR1B	intracellular protein-containing complex
REAC:R-HSA-73863	6.58415848923e-25	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	RNA Polymerase I Transcription Termination
REAC:R-HSA-73762	1.683638635e-24	0.388888888889	POLR1E POLR1G RRN3 POLR2F POLR1A POLR2E POLR1H POLR1C POLR1D POLR2K POLR1B POLR2L POLR1F POLR2H	RNA Polymerase I Transcription Initiation
WP:WP405	1.56157723398e-23	0.361111111111	POLR3B POLR2H POLR1E POLR2K POLR1A POLR3K POLR3D POLR1D POLR3E POLR1B POLR3H POLR2E POLR2F	Eukaryotic transcription initiation
GO:0001054	1.04048404392e-22	0.277777777778	POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR2H	RNA polymerase I activity
GO:0001056	1.04048404392e-22	0.277777777778	POLR3A POLR2H POLR3B POLR2K POLR2F POLR3K POLR1D POLR2L POLR2E POLR1C	RNA polymerase III activity
WP:WP5222	8.09696824029e-22	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	2q13 copy number variation syndrome
REAC:R-HSA-73772	5.86086549373e-21	0.388888888889	POLR1E POLR1G RRN3 POLR2F POLR1A POLR2E POLR1H POLR1C POLR1D POLR2K POLR1B POLR2L POLR1F POLR2H	RNA Polymerase I Promoter Escape
REAC:R-HSA-73854	1.49615449277e-19	0.388888888889	POLR1E POLR1G RRN3 POLR2F POLR1A POLR2E POLR1H POLR1C POLR1D POLR2K POLR1B POLR2L POLR1F POLR2H	RNA Polymerase I Promoter Clearance
REAC:R-HSA-73864	1.7401173893e-19	0.388888888889	POLR1E POLR1G RRN3 POLR2F POLR1A POLR2E POLR1H POLR1C POLR1D POLR2K POLR1B POLR2L POLR1F POLR2H	RNA Polymerase I Transcription
REAC:R-HSA-5250924	6.56982933988e-19	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	B-WICH complex positively regulates rRNA expression
GO:1990234	6.29468357921e-18	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	transferase complex
REAC:R-HSA-5250913	7.56519284302e-18	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	Positive epigenetic regulation of rRNA expression
REAC:R-HSA-427413	8.76646063635e-18	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	NoRC negatively regulates rRNA expression
REAC:R-HSA-74160	1.18599758517e-17	0.722222222222	POLR2H POLR3E CRCP POLR1E POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL POLR1F POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B	Gene expression (Transcription)
REAC:R-HSA-5250941	1.35052852082e-17	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	Negative epigenetic regulation of rRNA expression
GO:0006383	2.09147419165e-17	0.333333333333	POLR3G POLR3K POLR2F POLR3C POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR3GL POLR2L	transcription by RNA polymerase III
GO:0140098	2.10090401427e-16	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	catalytic activity, acting on RNA
GO:1990062	4.82023188108e-15	0.222222222222	RPAP3 PFDN6 DNAAF10 URI1 UXT PDRG1 POLR2E PIH1D1	RPAP3/R2TP/prefoldin-like complex
GO:0140513	2.54521909343e-14	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	nuclear protein-containing complex
REAC:R-HSA-212165	2.79397932858e-14	0.361111111111	POLR1E POLR2H POLR1C POLR2K POLR2F POLR1A POLR2E POLR1H POLR1D POLR1B POLR2L POLR1F POLR1G	Epigenetic regulation of gene expression
GO:0140640	6.31968668217e-13	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	catalytic activity, acting on a nucleic acid
GO:1902494	4.43538859796e-11	0.666666666667	POLR2H POLR3E POLR3GL CRCP POLR1E POLR3H POLR3G POLR1C POLR3D POLR2K POLR1A POLR2L POLR1D POLR1H POLR1G POLR3A POLR3F POLR1F POLR2E POLR3B POLR3K POLR2F POLR3C POLR1B	catalytic complex
CORUM:2685	8.10916622846e-11	0.166666666667	POLR2H POLR2K POLR2L RPAP1 POLR2E POLR2F	RNA polymerase II (RNAPII)
REAC:R-HSA-168249	1.08587001696e-10	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	Innate Immune System
GO:0016772	2.53073210009e-10	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	transferase activity, transferring phosphorus-containing groups
CORUM:5233	1.98661134992e-09	0.166666666667	POLR1G POLR1E POLR1A POLR1B POLR2L POLR2H	TNF-alpha/NF-kappa B signaling complex 5
CORUM:104	3.22394940913e-09	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II core complex
CORUM:2686	5.90012245025e-09	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	BRCA1-core RNA polymerase II complex
GO:0006360	5.16790294516e-08	0.222222222222	POLR1C RRN3 POLR1E POLR1H PIH1D1 POLR2K POLR2L POLR2F	transcription by RNA polymerase I
CORUM:103	1.4641137929e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II holoenzyme complex
REAC:R-HSA-8851708	1.78762560605e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Signaling by FGFR2 IIIa TM
CORUM:2825	2.55314518022e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	BRCA1-RNA polymerase II complex
GO:0032991	2.74838486415e-07	0.888888888889	POLR2H POLR3E CRCP POLR1E POLR1C PIH1D1 POLR3H POLR3A POLR3C GPN3 POLR1H POLR2K POLR1A POLR2L UXT POLR3F PDRG1 POLR1D POLR1G POLR3G POLR3GL DNAAF10 URI1 RPAP3 POLR2E PFDN6 POLR3B POLR3K POLR2F POLR3D POLR1B POLR1F	protein-containing complex
GO:0001055	4.24700324456e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II activity
REAC:R-HSA-167242	5.45555829578e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Abortive elongation of HIV-1 transcript in the absence of Tat
REAC:R-HSA-203927	6.95866344133e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	MicroRNA (miRNA) biogenesis
REAC:R-HSA-5601884	6.95866344133e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	PIWI-interacting RNA (piRNA) biogenesis
GO:0031981	8.38078912513e-07	0.805555555556	POLR2H POLR3E CRCP POLR1E PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B POLR1F	nuclear lumen
REAC:R-HSA-6803529	8.77434623277e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	FGFR2 alternative splicing
REAC:R-HSA-1839126	8.77434623277e-07	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	FGFR2 mutant receptor activation
REAC:R-HSA-77075	1.35313586597e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Pol II CTD phosphorylation and interaction with CE
REAC:R-HSA-167160	1.35313586597e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
GO:0005654	1.67434963273e-06	0.777777777778	POLR2H POLR3E CRCP POLR1E POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR3K UXT POLR3F POLR2L POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR2F RRN3 POLR3D POLR1B POLR1F	nucleoplasm
REAC:R-HSA-72086	2.01453692844e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	mRNA Capping
REAC:R-HSA-167243	2.91075572814e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Tat-mediated HIV elongation arrest and recovery
REAC:R-HSA-167238	2.91075572814e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Pausing and recovery of Tat-mediated HIV elongation
GO:0032728	3.2855492381e-06	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	positive regulation of interferon-beta production
REAC:R-HSA-5655253	3.46437870951e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Signaling by FGFR2 in disease
REAC:R-HSA-113418	4.09866878053e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of the Early Elongation Complex
REAC:R-HSA-167290	4.09866878053e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Pausing and recovery of HIV elongation
REAC:R-HSA-167287	4.09866878053e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	HIV elongation arrest and recovery
REAC:R-HSA-167158	4.09866878053e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of the HIV-1 Early Elongation Complex
GO:0005665	4.30740859998e-06	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II, core complex
REAC:R-HSA-168256	4.44910075479e-06	0.5	POLR3B POLR3K POLR3C POLR2H POLR1C POLR3A POLR2K POLR3E CRCP POLR3H POLR3D POLR3F POLR1D POLR3GL POLR3G POLR2L POLR2E POLR2F	Immune System
HP:0000652	5.3774529555e-06	0.111111111111	POLR1B POLR1D POLR1C POLR1A	Lower eyelid coloboma
GO:0005730	7.83660323628e-06	0.416666666667	POLR1E POLR1D POLR2H RRN3 POLR1G POLR2F POLR1A POLR2E POLR1H PIH1D1 POLR2K POLR1B POLR2L POLR1F POLR1C	nucleolus
GO:0006351	1.27108966048e-05	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	DNA-templated transcription
REAC:R-HSA-168325	1.32043210371e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Viral Messenger RNA Synthesis
GO:0032774	1.58458553156e-05	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	RNA biosynthetic process
REAC:R-HSA-167200	1.70101204405e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of HIV-1 elongation complex containing HIV-1 Tat
REAC:R-HSA-167169	1.70101204405e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	HIV Transcription Elongation
REAC:R-HSA-167246	1.70101204405e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Tat-mediated elongation of the HIV-1 transcript
KEGG:03420	1.865808569e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Nucleotide excision repair
REAC:R-HSA-167152	2.16392740408e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of HIV elongation complex in the absence of HIV Tat
REAC:R-HSA-167162	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II HIV Promoter Escape
REAC:R-HSA-76042	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Transcription Initiation And Promoter Clearance
REAC:R-HSA-73776	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Promoter Escape
REAC:R-HSA-73779	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REAC:R-HSA-75953	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Transcription Initiation
REAC:R-HSA-167161	2.43011253773e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	HIV Transcription Initiation
GO:0032648	3.04489701814e-05	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	regulation of interferon-beta production
GO:0032608	3.04489701814e-05	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	interferon-beta production
REAC:R-HSA-72165	3.38778006822e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	mRNA Splicing - Minor Pathway
REAC:R-HSA-1226099	4.17713400699e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Signaling by FGFR in disease
REAC:R-HSA-6781823	5.10573796844e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of TC-NER Pre-Incision Complex
REAC:R-HSA-5654738	6.79793342672e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Signaling by FGFR2
REAC:R-HSA-9670095	6.79793342672e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Inhibition of DNA recombination at telomere
REAC:R-HSA-75955	8.15320763405e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Transcription Elongation
REAC:R-HSA-112382	8.15320763405e-05	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Formation of RNA Pol II elongation complex
REAC:R-HSA-6796648	0.000115025373052	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	TP53 Regulates Transcription of DNA Repair Genes
REAC:R-HSA-190236	0.000124893999251	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Signaling by FGFR
REAC:R-HSA-6782210	0.000135420748991	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Gap-filling DNA repair synthesis and ligation in TC-NER
REAC:R-HSA-6782135	0.000146637231292	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Dual incision in TC-NER
GO:0032481	0.000191527246376	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	positive regulation of type I interferon production
REAC:R-HSA-167172	0.000199065591279	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Transcription of the HIV genome
GO:0034654	0.000205249782815	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	nucleobase-containing compound biosynthetic process
GO:0070013	0.000239517484451	0.805555555556	POLR2H POLR3E CRCP POLR1E PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B POLR1F	intracellular organelle lumen
GO:0043233	0.000239517484451	0.805555555556	POLR2H POLR3E CRCP POLR1E PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B POLR1F	organelle lumen
GO:0031974	0.000239517484451	0.805555555556	POLR2H POLR3E CRCP POLR1E PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B POLR1F	membrane-enclosed lumen
REAC:R-HSA-6807505	0.000265305522327	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II transcribes snRNA genes
GO:0098781	0.000283838622664	0.194444444444	POLR1G POLR3E POLR1E POLR3D PIH1D1 POLR2L POLR2F	ncRNA transcription
GO:0018130	0.00029642586527	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	heterocycle biosynthetic process
GO:0019438	0.000302830911395	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	aromatic compound biosynthetic process
HPA:0470683	0.000304594204491	0.333333333333	POLR3B POLR2H POLR3G RRN3 URI1 POLR3E POLR1A POLR1E RPAP3 UXT RPAP1 PIH1D1	skin 2; epidermal cells[High]
GO:0042797	0.000322081911533	0.111111111111	POLR3D POLR3E POLR2F POLR2L	tRNA transcription by RNA polymerase III
REAC:R-HSA-6781827	0.000371342523822	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
REAC:R-HSA-674695	0.000422088786872	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA Polymerase II Pre-transcription Events
GO:0009304	0.000505242014007	0.111111111111	POLR3D POLR3E POLR2F POLR2L	tRNA transcription
GO:1901362	0.000541414202465	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	organic cyclic compound biosynthetic process
HP:0000561	0.000725734044658	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Absent eyelashes
GO:0050821	0.000780139631226	0.222222222222	RPAP3 PFDN6 DNAAF10 URI1 UXT PDRG1 POLR2E PIH1D1	protein stabilization
WP:WP5362	0.000786233722322	0.111111111111	POLR3G POLR3GL POLR3C POLR3F	TAR syndrome
REAC:R-HSA-5578749	0.000852636821739	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Transcriptional regulation by small RNAs
HPA:0620222	0.000963021523763	0.611111111111	POLR2H POLR3E POLR1A PIH1D1 POLR3H POLR3G POLR3D POLR1E POLR2E UXT POLR1G RPAP3 DNAAF10 URI1 POLR3K PFDN6 POLR3B POLR2F RRN3 POLR1H RPAP1 POLR1F	vagina; squamous epithelial cells[>=Medium]
CORUM:1558	0.00112154545115	0.0555555555556	RRN3 POLR1B	POLR1B-RRN3 complex
HP:0002550	0.00112731764174	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Absent facial hair
GO:0016740	0.00123096031759	0.5	POLR3G POLR3B POLR1A POLR3C POLR2H POLR1C POLR3A POLR2K POLR2E CRCP POLR3H POLR1H POLR1D POLR3F POLR1B POLR2L POLR3K POLR2F	transferase activity
REAC:R-HSA-157579	0.00135853506842	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Telomere Maintenance
HP:0000625	0.00147405490322	0.111111111111	POLR1B POLR1D POLR1C POLR1A	Eyelid coloboma
REAC:R-HSA-5619507	0.00180933049279	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Activation of HOX genes during differentiation
REAC:R-HSA-5617472	0.00180933049279	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Activation of anterior HOX genes in hindbrain development during early embryogenesis
HP:0000778	0.00189436995138	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Hypoplasia of the thymus
REAC:R-HSA-5696398	0.00198312368648	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Nucleotide Excision Repair
GO:0101031	0.00209948704489	0.138888888889	PDRG1 URI1 RPAP3 PFDN6 UXT	protein folding chaperone complex
HP:0009795	0.00226067508393	0.0833333333333	POLR1B POLR1C POLR1D	Branchial fistula
HP:0005701	0.00226067508393	0.0833333333333	POLR1B POLR1C POLR1D	Multiple enchondromatosis
REAC:R-HSA-211000	0.00305809441564	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Gene Silencing by RNA
HPA:0330222	0.00330788487117	0.611111111111	POLR2H POLR3E POLR1A PIH1D1 POLR3H POLR3G POLR3D POLR1E POLR2E UXT POLR1G RPAP3 DNAAF10 URI1 POLR3K PFDN6 POLR3B POLR2F RRN3 POLR1H RPAP1 POLR1F	oral mucosa; squamous epithelial cells[>=Medium]
HP:0011226	0.00333047945122	0.111111111111	POLR1B POLR1D POLR1C POLR1A	Aplasia/Hypoplasia of the eyelid
HP:0010515	0.00333047945122	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Aplasia/Hypoplasia of the thymus
CORUM:1557	0.00335941736415	0.0555555555556	RRN3 POLR1B	NMI-POLR1B-RRN3 complex
HPA:0340461	0.00362172704759	0.583333333333	POLR3B POLR3K POLR2H POLR2F URI1 POLR1H POLR1E RRN3 POLR1G POLR3E CRCP POLR1A POLR3D POLR1F UXT PIH1D1 RPAP1 RPAP3 POLR3H POLR2E PFDN6	ovary; ovarian stroma cells[>=Low]
GO:0016070	0.00435771045205	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	RNA metabolic process
REAC:R-HSA-9018519	0.00437331546665	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Estrogen-dependent gene expression
REAC:R-HSA-73886	0.00437331546665	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Chromosome Maintenance
GO:0032479	0.00441333252254	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	regulation of type I interferon production
GO:0032606	0.00441333252254	0.166666666667	POLR3G POLR3B POLR3F POLR3C POLR3D POLR3A	type I interferon production
REAC:R-HSA-162599	0.00489789450187	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Late Phase of HIV Life Cycle
REAC:R-HSA-168273	0.00508324414458	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Influenza Viral RNA Transcription and Replication
HP:0002006	0.00536062292422	0.0833333333333	POLR1B POLR1C POLR1D	Tessier cleft
REAC:R-HSA-162587	0.00750569279591	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	HIV Life Cycle
HP:0002298	0.0077555737177	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Absent hair
HP:0011386	0.0084994154175	0.0833333333333	POLR1B POLR1C POLR1D	Narrow internal auditory canal
REAC:R-HSA-168255	0.00916026979718	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Influenza Infection
HP:0002692	0.00990829554722	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Hypoplastic facial bones
HP:0011219	0.0104431127951	0.0833333333333	POLR1B POLR1C POLR1D	Short face
GO:0044271	0.0106075560723	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	cellular nitrogen compound biosynthetic process
GO:0031647	0.0114912800388	0.222222222222	RPAP3 PFDN6 DNAAF10 URI1 UXT PDRG1 POLR2E PIH1D1	regulation of protein stability
HP:0034261	0.0115696146413	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Aplasia/Hypoplasia of facial bones
GO:0005634	0.0124371660605	0.805555555556	POLR2H POLR3E CRCP POLR1E PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR1H POLR2K POLR1A POLR2L UXT POLR3F POLR1D POLR1G POLR3G POLR3GL GPN1 URI1 POLR2E POLR3B POLR3K POLR2F RRN3 POLR3D POLR1B POLR1F	nucleus
HP:0000777	0.012473309334	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Abnormal thymus morphology
HP:0009804	0.0126008967051	0.194444444444	POLR3B POLR1C POLR3A POLR3GL POLR1D POLR1B POLR3K	Tooth agenesis
HP:0009794	0.015165641856	0.0833333333333	POLR1B POLR1C POLR1D	Branchial anomaly
HPA:0320103	0.0167142957614	0.361111111111	POLR3B PFDN6 RPAP3 RRN3 URI1 POLR2F POLR3E POLR1A POLR2E UXT RPAP1 POLR3K POLR2H	nasopharynx; respiratory epithelial cells[High]
HP:0000143	0.0179787224153	0.0833333333333	POLR1B POLR1C POLR1D	Rectovaginal fistula
HP:0011384	0.0179787224153	0.0833333333333	POLR1B POLR1C POLR1D	Abnormality of the internal auditory canal
HPA:0440342	0.0191818319908	0.527777777778	POLR3B POLR3K POLR2F DNAAF10 POLR1H POLR1E RRN3 POLR1G POLR3E CRCP POLR1A POLR3D POLR1F UXT RPAP1 RPAP3 POLR3H POLR2E POLR2H	skeletal muscle; myocytes[>=Medium]
HPA:0630222	0.0204548793994	0.527777777778	POLR3B POLR2H PFDN6 URI1 POLR1H POLR1E UXT POLR1G POLR1A POLR3K POLR3D POLR1F PIH1D1 POLR3E POLR3G RPAP3 POLR3H POLR2E POLR2F	cervix; squamous epithelial cells[>=Medium]
HPA:0060103	0.0205597041829	0.361111111111	POLR3B POLR2H RPAP3 RRN3 POLR2F POLR3E POLR1A URI1 POLR1H PIH1D1 RPAP1 POLR2E UXT	bronchus; respiratory epithelial cells[High]
HP:0030038	0.0211156453092	0.0833333333333	POLR1B POLR1C POLR1D	Enchondroma
HP:0005990	0.0211156453092	0.0833333333333	POLR1B POLR1C POLR1D	Thyroid hypoplasia
HP:0000162	0.0211156453092	0.0833333333333	POLR1B POLR1C POLR1D	Glossoptosis
HP:0033079	0.0245932343755	0.0833333333333	POLR1B POLR1C POLR1D	Aplasia/Hypoplasia of the thyroid gland
HP:0006483	0.0247064439654	0.194444444444	POLR3B POLR1C POLR3A POLR3GL POLR1D POLR1B POLR3K	Abnormal number of teeth
HPA:0570771	0.0248505279528	0.222222222222	POLR3B POLR2H RPAP3 RRN3 POLR2E UXT RPAP1 POLR3H	testis; peritubular cells[>=Low]
REAC:R-HSA-8939211	0.0265443228702	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	ESR-mediated signaling
GO:0016591	0.0316514290134	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	RNA polymerase II, holoenzyme
HP:0100590	0.03263711051	0.0833333333333	POLR1B POLR1C POLR1D	Rectal fistula
KEGG:05016	0.0327714881367	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	Huntington disease
HPA:0340000	0.0330901519937	0.638888888889	POLR2H POLR3E CRCP POLR1A PIH1D1 POLR3H POLR3G POLR3D POLR1E POLR2E UXT PDRG1 POLR1G RPAP3 URI1 POLR1F POLR3K PFDN6 POLR3B POLR2F RRN3 POLR1H RPAP1	ovary
REAC:R-HSA-72163	0.0392357029894	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	mRNA Splicing - Major Pathway
CORUM:781	0.0399394623246	0.0555555555556	POLR2E URI1	URI complex (Unconventional prefoldin RPB5 Interactor)
HP:0200102	0.0415235803675	0.111111111111	POLR3A POLR1D POLR1C POLR1B	Sparse or absent eyelashes
HPA:0460662	0.0432401534349	0.472222222222	POLR3B POLR3K POLR2H POLR3G POLR1E RRN3 URI1 POLR3E CRCP POLR1A POLR3D PIH1D1 RPAP1 RPAP3 POLR3H POLR1F UXT	skin 1; keratinocytes[>=Medium]
HPA:0270351	0.0460258339299	0.611111111111	POLR2H POLR3E CRCP POLR1A PIH1D1 POLR3H RPAP3 POLR3D POLR1E POLR2E UXT PDRG1 DNAAF10 URI1 POLR3K PFDN6 POLR3B POLR2F RRN3 POLR1H RPAP1 POLR1F	kidney; cells in glomeruli[>=Low]
REAC:R-HSA-72172	0.0460648824987	0.138888888889	POLR2K POLR2H POLR2F POLR2E POLR2L	mRNA Splicing
GO:0090304	0.0465337745645	0.638888888889	POLR2H POLR3E CRCP PIH1D1 POLR3H POLR3A POLR3C POLR1C POLR3D POLR2K POLR1E POLR2L UXT POLR3F POLR1G POLR3G POLR3GL URI1 POLR3K POLR2E POLR2F RRN3 POLR1H	nucleic acid metabolic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
POLR3H	POLR3C	1.0	0.176	structurally_consistent (O14802) structurally_consistent (dimer)
POLR3H	POLR3B	1.0	0.232	structurally_consistent (dimer)
POLR3H	POLR3F	1.0	0.504
POLR3K	POLR3C	1.0	0.118	structurally_consistent (O14802) structurally_consistent (dimer)
DNAAF10	RPAP3	1.0	0.106	structurally_consistent (dimer)
PIH1D1	RPAP3	1.0	0.534	mutually_exclusive (Q96MX6) structurally_consistent (dimer)
POLR1D	POLR1C	1.0	0.898	structurally_consistent (O95602) structurally_consistent (dimer)
POLR2F	POLR1G	1.0	0.226
URI1	RPAP3	1.0	0.034	mutually_exclusive (Q96MX6)
POLR1B	POLR1D	1.0	0.264
UXT	URI1	1.0	0.23	mutually_exclusive (O15212)
POLR1G	POLR1D	1.0	0.256
POLR3K	POLR3F	1.0	0.184
POLR3F	POLR3G	1.0	0.088
CRCP	POLR3B	1.0	0.044	structurally_consistent (dimer)
POLR2F	POLR1E	1.0	0.346	structurally_consistent (O95602)
POLR3H	POLR3A	1.0	0.328	structurally_consistent (dimer)
POLR1E	POLR1D	1.0	0.304	structurally_consistent (O95602)
PIH1D1	DNAAF10	1.0	0.128	structurally_consistent (dimer)
CRCP	POLR3A	1.0	0.288
POLR3D	POLR3C	1.0	0.13
UXT	RPAP3	1.0	0.086
POLR3A	POLR3B	1.0	0.194	structurally_consistent (dimer)
POLR3H	POLR3G	1.0	0.114
POLR1B	POLR1C	1.0	0.538
POLR1G	POLR1E	1.0	0.744
POLR3H	POLR1C	1.0	0.206	structurally_consistent (Q9NW08)
CRCP	POLR3C	1.0	0.22
PIH1D1	URI1	1.0	0.066	mutually_exclusive (Q96MX6)
UXT	PDRG1	1.0	0.45
POLR3H	POLR3E	1.0	0.294	structurally_consistent (Q9NW08)
POLR2F	POLR3F	1.0	0.512
CRCP	POLR3F	1.0	0.106
CRCP	POLR3H	1.0	0.308	structurally_consistent (dimer)
POLR1A	POLR1D	1.0	0.478	structurally_consistent (dimer)
POLR3GL	POLR3C	1.0	0.066	structurally_consistent (dimer)
POLR3F	POLR3C	1.0	0.234	structurally_consistent (dimer)
POLR3G	POLR3C	1.0	0.076	structurally_consistent (dimer)
POLR3K	POLR1C	1.0	0.352
POLR3GL	POLR3F	1.0	0.112
UXT	DNAAF10	1.0	0.558
RPAP1	GPN2	1.0	0.092
POLR3D	POLR1D	1.0	0.118
POLR3H	POLR3D	1.0	0.246
POLR2E	POLR3H	1.0	0.222
PIH1D1	PDRG1	1.0	0.172
POLR3K	POLR3G	1.0	0.19
CRCP	POLR3K	1.0	0.162	mutually_exclusive (Q9HCN4)
POLR3F	POLR1D	1.0	0.12
POLR3H	GPN1	1.0	0.276	mutually_exclusive (O75575)
POLR2F	POLR1D	1.0	0.478	structurally_consistent (O95602)
POLR3F	POLR3B	1.0	0.082	structurally_consistent (dimer)
POLR2F	POLR3C	1.0	0.508	structurally_consistent (O14802)
PIH1D1	UXT	1.0	0.12
POLR3G	POLR3B	1.0	0.064	structurally_consistent (dimer)
POLR2H	POLR3K	1.0	0.17
POLR2F	POLR1B	1.0	0.34
POLR3D	POLR3B	1.0	0.11
PDRG1	RPAP3	1.0	0.162
POLR3A	POLR3F	1.0	0.328
POLR2E	POLR3K	1.0	0.29
POLR3K	POLR1D	1.0	0.104
URI1	PDRG1	1.0	0.24
POLR3G	POLR1D	1.0	0.076	structurally_consistent (Q9BUI4)
POLR2F	POLR2H	1.0	0.776	structurally_consistent (P24928)
POLR3C	POLR2L	1.0	0.22	structurally_consistent (Q9NW08)
POLR1G	POLR1C	1.0	0.282
POLR3A	POLR3G	1.0	0.076
POLR1B	POLR1A	1.0	0.842	structurally_consistent (dimer)
POLR3H	POLR2H	1.0	0.206	structurally_consistent (O14802)
POLR3D	POLR3GL	1.0	0.092
POLR3H	POLR1D	1.0	0.102	structurally_consistent (Q9BUI4)
POLR3C	POLR1D	1.0	0.132	structurally_consistent (dimer)
POLR3H	POLR3K	1.0	0.152	structurally_consistent (O14802)
GPN1	GPN2	1.0	0.14	structurally_consistent (dimer)
POLR3D	POLR3A	1.0	0.196
POLR3E	POLR1D	1.0	0.108
POLR3D	POLR3F	1.0	0.336
POLR1A	POLR1C	1.0	0.266	mutually_exclusive (Q9NW08) structurally_consistent (dimer)
POLR3GL	POLR3E	1.0	0.112
POLR1D	POLR3B	1.0	0.06	structurally_consistent (Q9BUI4)
CRCP	POLR1D	1.0	0.162
POLR1E	POLR1C	1.0	0.57
POLR2H	GPN1	1.0	0.162
POLR2E	DNAAF10	1.0	0.178
POLR3K	POLR3B	1.0	0.084
POLR2F	POLR1A	1.0	0.212	structurally_consistent (dimer)
POLR3C	POLR3B	1.0	0.104	structurally_consistent (dimer)
POLR3D	POLR2H	1.0	0.154
POLR3K	GPN1	1.0	0.18	structurally_consistent (dimer)
POLR3A	POLR3C	0.999	0.272	structurally_consistent (dimer)
POLR3K	POLR3E	0.999	0.166
POLR3H	POLR3GL	0.999	0.168
POLR3B	POLR1C	0.999	0.178	structurally_consistent (dimer)
POLR2E	POLR2H	0.999	0.966	structurally_consistent (O95602)
POLR1D	GPN1	0.999	0.084	structurally_consistent (O15160)
POLR2F	POLR1C	0.999	0.568
POLR2L	GPN2	0.999	0.14	structurally_consistent (P30876)
POLR2H	POLR1D	0.999	0.354
POLR2E	POLR3D	0.999	0.142
POLR2E	POLR1A	0.999	0.31	structurally_consistent (dimer)
POLR3A	POLR3K	0.999	0.217	structurally_consistent (dimer)
POLR3A	POLR3GL	0.999	0.086
POLR3GL	POLR3K	0.999	0.138
POLR3A	POLR1C	0.999	0.164
CRCP	POLR3G	0.999	0.09
POLR2E	POLR2F	0.999	0.864	structurally_consistent (P62487) structurally_consistent (dimer)
POLR3D	POLR2K	0.999	0.37
POLR2H	POLR2L	0.999	0.916	structurally_consistent (P30876) structurally_consistent (dimer)
POLR2E	POLR3B	0.999	0.1348
POLR1A	POLR1F	0.999	0.512	structurally_consistent (dimer)
POLR3E	POLR3C	0.999	0.228	structurally_consistent (dimer)
POLR1A	POLR1E	0.999	0.572	structurally_consistent (dimer)
POLR2K	POLR1D	0.999	0.454	structurally_consistent (Q9BUI4)
POLR3GL	POLR3B	0.999	0.1	structurally_consistent (dimer)
POLR3F	POLR2L	0.999	0.328	structurally_consistent (Q9NW08)
GPN3	POLR2H	0.999	0.084
PIH1D1	POLR3K	0.999	0.12
RRN3	POLR1A	0.999	0.08	structurally_consistent (dimer)
POLR2L	POLR2A	0.999	0.714
POLR3D	POLR3E	0.999	0.714
POLR2E	PDRG1	0.999	0.274
POLR2E	CRCP	0.999	0.406
CRCP	POLR1C	0.999	0.388
POLR2E	PIH1D1	0.999	0.298	structurally_consistent (dimer)
POLR1G	POLR2L	0.999	0.306
POLR3H	POLR2K	0.999	0.442	structurally_consistent (Q9NW08)
POLR3D	POLR3G	0.999	0.112
DNAAF10	URI1	0.999	0.122	structurally_consistent (dimer)
POLR3B	GPN1	0.999	0.018
POLR2K	POLR3K	0.999	0.3058	structurally_consistent (Q9BUI4)
POLR2K	GPN1	0.999	0.276
PFDN6	UXT	0.999	0.332	structurally_consistent (dimer)
POLR2K	POLR1C	0.999	0.606	structurally_consistent (dimer)
POLR3A	POLR1D	0.999	0.152	structurally_consistent (Q9BUI4)
POLR3G	POLR2L	0.999	0.136
POLR3D	GPN1	0.999	0.046
POLR2F	POLR3K	0.999	0.262	structurally_consistent (O14802)
POLR2F	POLR3H	0.999	0.436
POLR1G	POLR1A	0.999	0.678
PFDN6	PDRG1	0.999	0.432
GPN3	POLR3G	0.999	0.118
POLR2E	GPN3	0.999	0.108
POLR1D	POLR1F	0.999	0.216	structurally_consistent (O95602)
CRCP	POLR3E	0.999	0.408	structurally_consistent (Q9NW08)
POLR2H	POLR3GL	0.999	0.054
POLR3GL	POLR2L	0.999	0.104	structurally_consistent (Q9NW08)
POLR3D	POLR2L	0.999	0.236
RPAP1	POLR2L	0.999	0.14
POLR3D	POLR1C	0.999	0.07
POLR3A	POLR3E	0.999	0.432
POLR2L	POLR3B	0.999	0.148	structurally_consistent (dimer)
POLR2F	POLR1F	0.999	0.516
GPN3	GPN1	0.999	0.28	structurally_consistent (dimer)
POLR1F	POLR1C	0.999	0.408
POLR2F	POLR3A	0.999	0.2745	structurally_consistent (dimer)
POLR3D	RPAP3	0.999	0.088
CRCP	POLR3D	0.999	0.404	mutually_exclusive (P62487)
POLR2F	POLR3G	0.999	0.16
POLR1G	POLR1B	0.999	0.526	structurally_consistent (dimer)
GPN1	POLR2A	0.999	0.058
POLR3H	GPN3	0.999	0.196
POLR3GL	POLR1C	0.999	0.048	structurally_consistent (Q9NW08)
POLR1E	GPN1	0.999	0.064
POLR2E	POLR1D	0.999	0.324
POLR2L	POLR1C	0.999	0.866	structurally_consistent (dimer)
GPN3	POLR1G	0.999	0.146
POLR2E	RPAP3	0.999	0.244
CRCP	POLR2L	0.999	0.168	structurally_consistent (Q9NW08)
GPN3	POLR1D	0.999	0.21
CRCP	POLR2F	0.999	0.342	structurally_consistent (P62487)
RPAP1	GPN1	0.999	0.122
GPN1	POLR1C	0.999	0.212	structurally_consistent (dimer)
POLR3K	POLR2L	0.999	0.44
POLR3C	POLR1C	0.999	0.274
POLR3H	POLR2L	0.999	0.406	structurally_consistent (Q9NW08)
POLR2K	POLR3B	0.999	0.126	structurally_consistent (Q9BUI4) structurally_consistent (dimer)
POLR2E	POLR2L	0.999	0.954	structurally_consistent (dimer)
CRCP	GPN1	0.999	0.16	mixed_interface
POLR2H	POLR3F	0.999	0.218
GPN3	UXT	0.999	0.186
POLR1G	POLR1H	0.999	0.456	structurally_consistent (Q9H9Y6)
POLR2L	GPN1	0.999	0.228
POLR2E	UXT	0.999	0.39	structurally_consistent (dimer)
POLR1B	POLR1F	0.998	0.302	structurally_consistent (dimer)
POLR2F	POLR3B	0.998	0.114	structurally_consistent (dimer)
POLR2E	GPN1	0.998	0.054
POLR3GL	POLR1D	0.998	0.076
POLR1D	POLR2L	0.998	0.53
POLR3E	POLR1C	0.998	0.26	structurally_consistent (dimer)
POLR2H	POLR1C	0.998	0.566
POLR3D	POLR1A	0.998	0.036
POLR1E	POLR2L	0.998	0.43
GPN3	POLR2A	0.998	0.15
GPN3	POLR1A	0.998	0.074
POLR2E	POLR3GL	0.998	0.124	structurally_consistent (dimer)
POLR2E	POLR1C	0.998	0.372	structurally_consistent (O95602)
POLR1A	POLR1H	0.998	0.482	structurally_consistent (dimer)
POLR2H	POLR3G	0.998	0.096
POLR2F	GPN1	0.998	0.192
POLR2E	POLR2K	0.998	0.864
UXT	GPN1	0.998	0.14
POLR3K	URI1	0.998	0.058
UXT	POLR3A	0.998	0.182	structurally_consistent (dimer)
POLR2F	POLR1H	0.998	0.338
POLR3A	POLR1A	0.998	0.182
POLR3G	GPN1	0.998	0.106
POLR3E	POLR3G	0.998	0.104
CRCP	POLR3GL	0.998	0.096
POLR3G	POLR1C	0.998	0.126	structurally_consistent (Q9NW08)
POLR3F	POLR1C	0.998	0.12
POLR3D	POLR3K	0.998	0.178
POLR2F	POLR2K	0.998	0.736
POLR2F	POLR2L	0.998	0.658
PIH1D1	POLR1C	0.998	0.218
GPN3	POLR3K	0.998	0.088
PIH1D1	GPN1	0.998	0.142	structurally_consistent (dimer)
CRCP	GPN3	0.998	0.12	mutually_exclusive (Q9HCN4)
RPAP3	POLR1C	0.998	0.296
POLR1A	POLR3B	0.998	0.200533333333	structurally_consistent (dimer)
POLR1B	POLR1E	0.998	0.562
POLR2F	POLR3E	0.998	0.532	structurally_consistent (Q9NW08)
GPN3	POLR1E	0.998	0.098
POLR3E	POLR3B	0.998	0.246	structurally_consistent (dimer)
GPN3	POLR3E	0.998	0.266
RRN3	POLR1E	0.998	0.088
RRN3	POLR1C	0.998	0.202	structurally_consistent (O95602)
PFDN6	RPAP3	0.998	0.278
UXT	POLR3K	0.998	0.166
POLR3A	POLR2K	0.998	0.198
GPN3	POLR2K	0.998	0.206
POLR3A	GPN1	0.997	0.064
POLR2E	URI1	0.997	0.12	structurally_consistent (dimer)
PIH1D1	PFDN6	0.997	0.244
POLR3A	POLR2L	0.997	0.228
POLR2H	POLR1E	0.997	0.4	structurally_consistent (O95602)
GPN3	POLR3D	0.997	0.202
POLR3K	DNAAF10	0.997	0.238
RPAP3	POLR3B	0.997	0.116
RPAP1	POLR1C	0.997	0.154
GPN3	POLR1C	0.997	0.338
POLR1G	GPN1	0.997	0.1
PIH1D1	POLR2H	0.997	0.284	structurally_consistent (O14802)
GPN3	POLR3F	0.997	0.12
DNAAF10	PDRG1	0.997	0.23
POLR3K	RPAP3	0.997	0.26
RRN3	POLR1G	0.997	0.118
POLR3E	GPN1	0.997	0.086	structurally_consistent (O15160)
POLR3F	GPN1	0.997	0.108
POLR2F	GPN3	0.997	0.436
POLR2H	POLR2K	0.997	0.808
RRN3	POLR2F	0.997	0.198
POLR1G	POLR3B	0.997	0.058
RRN3	POLR1D	0.997	0.102
POLR1B	POLR2L	0.997	0.284	structurally_consistent (dimer)
POLR1A	POLR3K	0.997	0.152
POLR1E	POLR1F	0.997	0.238	structurally_consistent (O95602)
POLR1G	POLR3A	0.997	0.136
POLR3C	GPN1	0.997	0.052
POLR2K	POLR1A	0.997	0.304	structurally_consistent (Q9H9Y6)
POLR3E	POLR2L	0.997	0.382
PIH1D1	POLR2L	0.997	0.234
POLR1A	GPN1	0.997	0.022
POLR2E	POLR2A	0.997	0.808	structurally_consistent (dimer)
POLR3E	POLR3F	0.997	0.33	structurally_consistent (Q9NW08)
URI1	GPN1	0.997	0.052
POLR2H	POLR3C	0.997	0.31	structurally_consistent (O14802) structurally_consistent (dimer)
POLR1H	POLR1E	0.997	0.34	structurally_consistent (O95602)
POLR1B	GPN1	0.997	0.062
POLR2H	POLR1G	0.997	0.23
POLR2F	POLR3D	0.996	0.36	structurally_consistent (P62487)
GPN3	POLR3C	0.996	0.248
POLR1G	POLR1F	0.996	0.126
POLR2E	POLR3C	0.996	0.152	structurally_consistent (O14802) structurally_consistent (dimer)
GPN3	POLR1B	0.996	0.12
RRN3	POLR1F	0.996	0.218
POLR2K	POLR3C	0.996	0.5305	structurally_consistent (Q9NW08) structurally_consistent (dimer)
POLR2H	POLR3E	0.996	0.204	structurally_consistent (Q9BUI4)
POLR1A	POLR2L	0.996	0.356
CRCP	POLR2K	0.996	0.328	structurally_consistent (Q9NW08)
GPN3	POLR3B	0.996	0.044
POLR2K	POLR2L	0.996	0.78
UXT	POLR1A	0.996	0.098
POLR1B	POLR3B	0.996	0.042
DNAAF10	POLR1C	0.996	0.13
URI1	POLR1C	0.996	0.082
POLR2E	POLR3E	0.996	0.172
POLR1H	POLR1D	0.996	0.476	structurally_consistent (O95602)
POLR2H	POLR1B	0.996	0.296
RRN3	POLR1B	0.996	0.094
POLR1H	POLR1C	0.996	0.428
POLR2H	POLR3B	0.995	0.098	structurally_consistent (O14802)
POLR2K	POLR3F	0.995	0.326	structurally_consistent (Q9NW08)
CRCP	POLR2H	0.995	0.292
POLR2E	POLR3A	0.995	0.254	structurally_consistent (dimer)
POLR2K	POLR3GL	0.995	0.212
POLR3D	POLR1E	0.995	0.08
POLR3K	POLR1E	0.995	0.112
POLR2E	POLR1B	0.995	0.464
POLR3GL	POLR3G	0.995	0.086	mutually_exclusive (Q9BUI4)
POLR1B	POLR1H	0.995	0.552	structurally_consistent (dimer)
POLR2F	PIH1D1	0.995	0.22
PIH1D1	POLR3A	0.995	0.09	structurally_consistent (dimer)
GPN3	POLR2L	0.995	0.256
POLR3H	POLR1G	0.995	0.146
POLR2E	RRN3	0.995	0.218	structurally_consistent (O95602)
POLR2F	POLR3GL	0.995	0.118
POLR2H	POLR1A	0.995	0.254	structurally_consistent (dimer)
GPN3	URI1	0.995	0.126
PIH1D1	POLR3B	0.994	0.046	structurally_consistent (dimer)
POLR3B	POLR2A	0.994	0.326	structurally_consistent (dimer)
POLR3H	POLR1E	0.994	0.138
POLR2E	POLR1G	0.994	0.146
POLR1B	POLR3K	0.994	0.064	mutually_exclusive (O14802)
POLR2H	POLR3A	0.994	0.21	structurally_consistent (dimer)
POLR3A	POLR1B	0.994	0.062	structurally_consistent (dimer)
PDRG1	POLR2A	0.994	0.202
URI1	POLR1D	0.994	0.032
POLR3D	POLR1B	0.994	0.05
POLR3H	POLR1A	0.993	0.084
POLR2K	POLR1H	0.993	0.318	structurally_consistent (Q9H9Y6)
PIH1D1	POLR1A	0.993	0.228	mutually_exclusive (P19388)
POLR1G	POLR3K	0.993	0.108
POLR3D	POLR1G	0.993	0.076
URI1	POLR2A	0.993	0.06	mutually_exclusive (P19388)
POLR3D	DNAAF10	0.993	0.048
DNAAF10	GPN1	0.993	0.05
POLR3A	POLR1E	0.993	0.148
POLR3D	URI1	0.993	0.152
POLR1D	RPAP3	0.993	0.26
GPN3	DNAAF10	0.993	0.044
POLR3K	PDRG1	0.993	0.108
POLR3D	UXT	0.992	0.094
DNAAF10	POLR2A	0.992	0.1
PIH1D1	POLR3D	0.992	0.022
RRN3	POLR1H	0.992	0.126	structurally_consistent (O95602)
POLR2E	POLR1H	0.992	0.41	structurally_consistent (O95602)
RPAP3	GPN1	0.991	0.122
POLR2K	POLR3E	0.991	0.454
POLR2H	RPAP3	0.991	0.614
POLR2E	POLR3G	0.991	0.082	structurally_consistent (dimer)
POLR1D	GPN2	0.991	0.07
GPN3	POLR3GL	0.99	0.13
POLR1F	POLR2L	0.99	0.358	structurally_consistent (Q9H9Y6)
POLR1E	POLR3B	0.989	0.11
POLR3A	RPAP3	0.989	0.114
POLR3K	POLR2A	0.989	0.318
POLR3D	PDRG1	0.989	0.11
POLR1A	POLR3E	0.989	0.05
PIH1D1	POLR1D	0.989	0.162
PIH1D1	POLR3E	0.988	0.064	structurally_consistent (Q9NW08) structurally_consistent (dimer)
POLR2H	POLR2A	0.988	0.618	structurally_consistent (dimer)
POLR2F	POLR2A	0.988	0.8061	mutually_exclusive (Q9NW08) structurally_consistent (dimer)
GPN3	POLR3A	0.988	0.072
UXT	POLR3B	0.987	0.074	structurally_consistent (dimer)
PIH1D1	POLR2A	0.987	0.192
POLR2E	POLR3F	0.987	0.298	structurally_consistent (Q9BUI4) structurally_consistent (dimer)
URI1	POLR2L	0.987	0.048	mutually_exclusive (P19388)
PDRG1	GPN1	0.987	0.108
POLR3D	POLR2A	0.986	0.202	structurally_consistent (P62487)
POLR2E	POLR1E	0.986	0.252	structurally_consistent (O95602)
RRN3	POLR2L	0.986	0.192
POLR2H	POLR1H	0.986	0.312
POLR3GL	GPN1	0.986	0.074
POLR1G	POLR2K	0.985	0.178	structurally_consistent (Q9H9Y6)
POLR2H	PDRG1	0.985	0.218
RPAP3	POLR2A	0.985	0.136
PIH1D1	POLR2K	0.985	0.282
POLR2K	POLR3G	0.985	0.188	structurally_consistent (Q9NW08)
UXT	POLR2A	0.984	0.17
POLR2K	POLR1E	0.984	0.42
URI1	POLR3B	0.984	0.082
PDRG1	POLR3B	0.984	0.194
PFDN6	DNAAF10	0.983	0.14
POLR1A	RPAP3	0.982	0.086
POLR3H	POLR1B	0.982	0.102
RRN3	POLR2H	0.981	0.138	structurally_consistent (O95602)
POLR2H	URI1	0.981	0.114
RRN3	POLR2K	0.98	0.248
POLR2K	POLR2A	0.98	0.802
PFDN6	GPN1	0.98	0.192
PDRG1	POLR2L	0.979	0.322
CRCP	POLR1G	0.978	0.086
POLR2K	PDRG1	0.978	0.2
UXT	POLR3E	0.977	0.172
POLR2K	RPAP3	0.977	0.382
POLR3A	POLR2A	0.976	0.138
POLR2K	URI1	0.976	0.364
PIH1D1	GPN3	0.975	0.138	mutually_exclusive (Q9HCN4)
UXT	POLR1D	0.975	0.14
POLR1G	POLR3GL	0.975	0.046
POLR1A	URI1	0.974	0.068	mutually_exclusive (P19388)
POLR3B	GPN2	0.974	0.068
POLR2E	POLR1F	0.974	0.484
DNAAF10	POLR3B	0.972	0.118
POLR1A	POLR3GL	0.972	0.086	mutually_exclusive (P19388)
DNAAF10	POLR1D	0.972	0.026
POLR3H	RPAP3	0.971	0.122
CRCP	POLR1E	0.97	0.146
POLR1E	POLR3E	0.969	0.122
POLR1G	POLR3E	0.969	0.124
PFDN6	POLR1C	0.969	0.568
RPAP3	POLR2L	0.968	0.538
POLR3GL	POLR1E	0.968	0.094
POLR1A	PDRG1	0.967	0.062
PDRG1	POLR1C	0.966	0.124
POLR2K	POLR1B	0.966	0.2	structurally_consistent (dimer)
POLR2K	POLR1F	0.964	0.548	structurally_consistent (Q9H9Y6)
PFDN6	URI1	0.963	0.07	structurally_consistent (dimer)
PFDN6	POLR2A	0.961	0.152
POLR2H	DNAAF10	0.961	0.17
POLR2E	PFDN6	0.96	0.144
POLR2H	POLR1F	0.96	0.486	structurally_consistent (O95602)
POLR3A	URI1	0.959	0.134	mutually_exclusive (P19388)
CRCP	POLR1A	0.958	0.128	mutually_exclusive (Q9NW08)
POLR1G	POLR3C	0.957	0.18
POLR2K	GPN2	0.956	0.324	structurally_consistent (P30876)
POLR3E	URI1	0.955	0.082
GPN3	RPAP3	0.955	0.232
UXT	POLR2H	0.954	0.218	structurally_consistent (O14802)
GPN3	PDRG1	0.952	0.21
POLR1A	POLR3G	0.952	0.132	mutually_exclusive (Q9NW08)
POLR1G	POLR3G	0.951	0.048
POLR1E	POLR3C	0.951	0.124
POLR1E	POLR3G	0.947	0.08
CRCP	POLR1B	0.946	0.034
POLR1G	POLR3F	0.945	0.06
UXT	POLR2L	0.943	0.196	structurally_consistent (Q9NW08)
POLR1B	POLR3GL	0.94	0.044
POLR2K	RPAP1	0.937	0.422702702703
POLR3H	POLR2A	0.935	0.356	mutually_exclusive (Q9NW08)
POLR3A	PDRG1	0.935	0.158
PFDN6	POLR3B	0.933	0.076
POLR1C	GPN2	0.932	0.074	structurally_consistent (P30876)
POLR1B	POLR3G	0.93	0.064
POLR1B	POLR3C	0.929	0.082	mutually_exclusive (P53803)
POLR1B	POLR3F	0.927	0.072
UXT	POLR1C	0.927	0.152
PFDN6	POLR2K	0.924	0.35
POLR1A	POLR3F	0.922	0.042	mutually_exclusive (P19388)
RRN3	GPN1	0.922	0.11
PFDN6	POLR3K	0.921	0.290666666667
POLR1A	POLR3C	0.919	0.284
GPN3	GPN2	0.914	0.118	mutually_exclusive (Q9HCN4)
POLR2K	DNAAF10	0.908	0.426
POLR2E	GPN2	0.903	0.166
POLR1E	POLR3F	0.902	0.082
POLR3C	POLR1F	0.901	0.164
POLR3E	POLR1F	0.9	0.092
POLR3K	POLR1F	0.9	0.084
POLR3H	POLR1F	0.9	0.264
POLR3D	POLR1F	0.9	0.132
POLR3E	POLR2A	0.899	0.292	structurally_consistent (Q9NW08)
POLR3G	RPAP3	0.898	0.128
GPN3	PFDN6	0.896	0.12
POLR3F	POLR1F	0.89	0.142
POLR3H	PIH1D1	0.889	0.162
POLR2F	URI1	0.889	0.114	mutually_exclusive (P19388)
RRN3	CRCP	0.889	0.11
RRN3	POLR3GL	0.883	0.114
POLR3H	PDRG1	0.87	0.234
POLR3G	POLR1F	0.868	0.098
POLR2F	RPAP3	0.868	0.208
POLR3GL	POLR1F	0.868	0.04
RRN3	POLR3C	0.867	0.082
RRN3	POLR3G	0.867	0.092
CRCP	POLR1F	0.863	0.174
RRN3	POLR3F	0.862	0.11
RRN3	POLR3E	0.86	0.192
POLR1F	POLR3B	0.856	0.092	mutually_exclusive (O95602)
RRN3	POLR3B	0.855	0.1	structurally_consistent (O95602)
RRN3	POLR3H	0.854	0.094
UXT	POLR1E	0.839	0.124
POLR1E	URI1	0.837	0.072
RRN3	POLR3D	0.837	0.064
RRN3	POLR3K	0.837	0.15
POLR3K	RPAP1	0.836	0.126
POLR1H	POLR1F	0.835	0.53
POLR1H	POLR2L	0.834	0.392	structurally_consistent (Q9H9Y6)
PFDN6	POLR1D	0.827	0.074
POLR3E	PDRG1	0.825	0.154
RRN3	POLR3A	0.814	0.13
POLR3K	GPN2	0.811	0.122
POLR3D	GPN2	0.811	0.106
POLR3D	PFDN6	0.809	0.126
POLR3G	POLR2A	0.807	0.138
POLR1B	POLR3E	0.804	0.072
POLR1E	GPN2	0.797	0.064
PIH1D1	POLR3GL	0.795	0.158
POLR3GL	RPAP3	0.794	0.118
URI1	POLR3G	0.794	0.102	mutually_exclusive (P19388)
POLR2F	GPN2	0.788	0.154
POLR1B	PDRG1	0.785	0.126
POLR1E	POLR2A	0.784	0.18
PIH1D1	POLR3G	0.783	0.12
CRCP	PIH1D1	0.782	0.262	mutually_exclusive (Q9HCN4)
RRN3	GPN3	0.775	0.058
RRN3	URI1	0.775	0.044
POLR1D	POLR2A	0.775	0.102
POLR3A	DNAAF10	0.768	0.106
DNAAF10	POLR2L	0.767	0.308
POLR3H	DNAAF10	0.762	0.122	structurally_consistent (dimer)
POLR1F	GPN1	0.755	0.05
POLR1D	PDRG1	0.754	0.188
POLR3A	POLR1F	0.753	0.05	mutually_exclusive (Q9H9Y6)
POLR1A	GPN2	0.753	0.03
DNAAF10	POLR3E	0.753	0.122
POLR2A	GPN2	0.75	0.232	mutually_exclusive (P30876)
POLR3D	RPAP1	0.75	0.086
POLR1G	POLR2A	0.75	0.344
POLR1G	RPAP3	0.74	0.262
CRCP	RPAP3	0.739	0.252
POLR3C	RPAP3	0.735	0.132
POLR1D	RPAP1	0.73	0.1
POLR1E	RPAP1	0.721	0.042
POLR1A	DNAAF10	0.719	0.022
POLR3A	GPN2	0.712	0.116	mutually_exclusive (P30876)
PIH1D1	POLR1B	0.71	0.074
RPAP1	POLR3B	0.705	0.026
POLR3C	POLR2A	0.699	0.12
POLR3H	URI1	0.694	0.314
PIH1D1	GPN2	0.69	0.106	mutually_exclusive (Q9HCN4)
POLR1B	GPN2	0.689	0.046
GPN3	POLR1H	0.681	0.264
POLR1E	RPAP3	0.68	0.236
PFDN6	POLR2H	0.676	0.398	mutually_exclusive (Q9GZS3)
POLR2H	GPN2	0.672	0.162
POLR3GL	URI1	0.655	0.064	mutually_exclusive (P19388)
PFDN6	POLR3A	0.649	0.038
POLR1H	GPN1	0.647	0.102
POLR1B	RPAP3	0.643	0.156
URI1	POLR3C	0.633	0.058
POLR3E	RPAP3	0.633	0.042	mutually_exclusive (Q9NWS0)
PIH1D1	POLR3F	0.632	0.112
POLR1B	URI1	0.618	0.058
POLR2F	PDRG1	0.609	0.19
PIH1D1	POLR1E	0.608	0.09
POLR1G	URI1	0.608	0.04
POLR1A	POLR2A	0.592	0.236	mutually_exclusive (P52434)
GPN3	POLR1F	0.591	0.202
PIH1D1	POLR1F	0.587	0.056
UXT	POLR1B	0.578	0.152
RRN3	PIH1D1	0.573	0.11
POLR1E	PDRG1	0.558	0.188
POLR3G	PDRG1	0.518	0.08
CRCP	URI1	0.513	0.108
PFDN6	POLR2L	0.482	0.494
POLR1C	POLR2A	0.473	0.2
PIH1D1	POLR3C	0.472	0.07
POLR3H	GPN2	0.454	0.172
POLR3E	GPN2	0.454	0.138
POLR1A	RPAP1	0.453	0.057	mutually_exclusive (P52434)
CRCP	POLR2A	0.449	0.26
POLR2F	RPAP1	0.442	0.144
PFDN6	POLR1A	0.44	0.096
POLR3A	RPAP1	0.437	0.098	mutually_exclusive (P52434)
POLR3H	RPAP1	0.414	0.2
POLR3F	POLR2A	0.413	0.252
UXT	POLR2K	0.409	0.352	structurally_consistent (Q9NW08)
URI1	POLR1F	0.397	0.092
POLR3E	RPAP1	0.392	0.094
RRN3	POLR2A	0.384	0.204
CRCP	GPN2	0.384	0.094	mutually_exclusive (Q9HCN4)
RRN3	RPAP1	0.381	0.128
CRCP	RPAP1	0.368	0.126
POLR1G	GPN2	0.361	0.048
DNAAF10	POLR3C	0.345	0.052	structurally_consistent (Q9Y535)
POLR1E	DNAAF10	0.342	0.072
POLR1G	RPAP1	0.336	0.054
POLR3C	RPAP1	0.329	0.13	mutually_exclusive (P52434)
PIH1D1	POLR1G	0.327	0.152
POLR3F	RPAP1	0.318	0.07
POLR2E	RPAP1	0.318	0.148
POLR1B	DNAAF10	0.318	0.07
POLR2F	PFDN6	0.313	0.3016	mutually_exclusive (Q9GZS3)
GPN3	RPAP1	0.31	0.136
POLR1F	RPAP1	0.303	0.044
POLR1G	DNAAF10	0.3	0.026
DNAAF10	POLR3G	0.296	0.096
POLR3GL	PDRG1	0.295	0.06
DNAAF10	GPN2	0.292	0.116
POLR3C	GPN2	0.292	0.116
POLR3F	GPN2	0.292	0.102
POLR1G	PDRG1	0.291	0.172
RPAP1	POLR2A	0.288	0.136	mutually_exclusive (P52434)
POLR1B	RPAP1	0.284	0.054
POLR3F	RPAP3	0.276	0.096
POLR1F	GPN2	0.267	0.064
RRN3	GPN2	0.267	0.086
POLR1B	POLR2A	0.256	0.328	structurally_consistent (dimer)
POLR3G	GPN2	0.255	0.116
POLR1F	RPAP3	0.254	0.096
PFDN6	RPAP1	0.234	0.068
POLR1H	POLR3F	0.232	0.192
POLR3A	POLR1H	0.232	0.316	mutually_exclusive (Q9H9Y6)
POLR3C	PDRG1	0.232	0.164
RRN3	RPAP3	0.231	0.142
POLR3GL	GPN2	0.23	0.116
POLR3G	RPAP1	0.225	0.074
POLR3GL	RPAP1	0.216	0.08
PFDN6	POLR3E	0.215	0.076
POLR3D	POLR1H	0.192	0.26
RRN3	PFDN6	0.192	0.12
POLR3H	POLR1H	0.192	0.246
POLR1H	POLR3C	0.192	0.352
CRCP	POLR1H	0.192	0.15
POLR3GL	POLR1H	0.192	0.106
POLR1H	POLR3G	0.192	0.088
POLR1H	POLR3K	0.192	0.13
CRCP	PDRG1	0.191	0.12
PIH1D1	RPAP1	0.187	0.224
POLR3GL	DNAAF10	0.186	0.07
URI1	GPN2	0.175	0.106
RRN3	DNAAF10	0.168	0.05
POLR3F	URI1	0.16	0.168
RRN3	PDRG1	0.148	0.106
PFDN6	GPN2	0.127	0.098
PFDN6	POLR1G	0.124	0.158
UXT	POLR3G	0.121	0.092
POLR2F	DNAAF10	0.113	0.37
UXT	GPN2	0.11	0.132
CRCP	DNAAF10	0.11	0.134
POLR3F	PDRG1	0.098	0.136
DNAAF10	POLR3F	0.097	0.174
POLR3GL	POLR2A	0.094	0.112
POLR3H	UXT	0.085	0.198
PFDN6	POLR1B	0.075	0.074
PFDN6	POLR1E	0.074	0.162
UXT	POLR1F	0.073	0.084
UXT	POLR3GL	0.069	0.102
UXT	POLR3F	0.066	0.12
RPAP3	RPAP1	0.065	0.27
URI1	RPAP1	0.063	0.064
POLR2F	UXT	0.063	0.216
PFDN6	POLR1H	0.063	0.168
POLR1H	URI1	0.063	0.058
POLR1H	RPAP3	0.063	0.104
PIH1D1	POLR1H	0.063	0.118
POLR1H	POLR3B	0.063	0.134	mutually_exclusive (O95602)
DNAAF10	POLR1F	0.058	0.024
CRCP	UXT	0.057	0.19
RRN3	UXT	0.056	0.102
UXT	POLR3C	0.056	0.138
POLR1H	PDRG1	0.049	0.172
DNAAF10	RPAP1	0.044	0.062
PFDN6	POLR1F	0.043	0.122
POLR1F	PDRG1	0.04	0.052
POLR1H	DNAAF10	0.039	0.08
POLR1H	POLR2A	0.039	0.406
POLR1F	POLR2A	0.035	0.426	mutually_exclusive (Q9H9Y6)
PFDN6	POLR3GL	0.034	0.078
POLR2H	RPAP1	0.028	0.35	structurally_consistent (dimer)
RPAP3	GPN2	0.021	0.11
CRCP	PFDN6	0.021	0.18
POLR3H	PFDN6	0.021	0.078
UXT	RPAP1	0.019	0.142
PFDN6	POLR3F	0.019	0.214
PDRG1	RPAP1	0.018	0.044
PFDN6	POLR3G	0.015	0.064
PFDN6	POLR3C	0.015	0.134
PDRG1	GPN2	0.012	0.11
UXT	POLR1G	0.01	0.172

Related Complexes

Genename	Complexes
POLR3B	huMAP3_03997.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
RRN3	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_09678.1 huMAP3_11092.1 huMAP3_14318.1 huMAP3_15085.1
CRCP	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2F	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR3H	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
PIH1D1	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2L	huMAP3_01444.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1C	huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR3D	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
PFDN6	huMAP3_00807.1 huMAP3_06426.1 huMAP3_06819.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_09234.1 huMAP3_10942.1 huMAP3_11092.1 huMAP3_14584.1 huMAP3_14626.1
GPN3	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
UXT	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2H	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1G	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR3A	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2K	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1B	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1A	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
GPN1	huMAP3_03997.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2A	huMAP3_06426.1 huMAP3_08487.1 huMAP3_09843.1 huMAP3_11092.1 huMAP3_14318.1
POLR3GL	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1H	huMAP3_00807.1 huMAP3_03112.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_09678.1 huMAP3_11092.1 huMAP3_14318.1 huMAP3_15085.1
POLR3K	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR2E	huMAP3_00789.1 huMAP3_00807.1 huMAP3_06426.1 huMAP3_07748.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
RPAP1	huMAP3_01444.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
GPN2	huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1E	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
DNAAF10	huMAP3_00807.1 huMAP3_03810.1 huMAP3_06426.1 huMAP3_06559.1 huMAP3_07938.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_09191.1 huMAP3_10656.1 huMAP3_11092.1 huMAP3_14318.1 huMAP3_14584.1
POLR3E	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR3F	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
URI1	huMAP3_00807.1 huMAP3_01029.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_13731.1 huMAP3_14318.1
POLR3G	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR3C	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1D	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
POLR1F	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1
PDRG1	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1 huMAP3_14626.1
RPAP3	huMAP3_00807.1 huMAP3_06426.1 huMAP3_08487.1 huMAP3_09057.1 huMAP3_11092.1 huMAP3_14318.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08487.1

Complex Portal: CPX-22594