hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08496.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COL4A6 | Collagen alpha-6(IV) chain | 5 | UniProt NCBI |
| COL12A1 | Collagen alpha-1(XII) chain | 5 | UniProt NCBI |
| C1QTNF6 | Complement C1q tumor necrosis factor-related protein 6 | 5 | UniProt NCBI |
| COL8A2 | Collagen alpha-2(VIII) chain (Endothelial collagen) | 5 | UniProt NCBI |
| MVP | Major vault protein (MVP) (Lung resistance-related protein) | 5 | UniProt NCBI |
| PARP4 | Protein mono-ADP-ribosyltransferase PARP4 (EC 2.4.2.-) (193 kDa vault protein) (ADP-ribosyltransferase diphtheria toxin-like 4) (ARTD4) (PARP-related/IalphaI-related H5/proline-rich) (PH5P) (Poly [ADP-ribose] polymerase 4) (PARP-4) (Vault poly(ADP-ribose) polymerase) (VPARP) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8948216 | 0.0065872694687 | 0.4 | COL4A6 COL12A1 | Collagen chain trimerization |
| KEGG:04974 | 0.0105666091545 | 0.4 | COL4A6 COL12A1 | Protein digestion and absorption |
| WP:WP4949 | 0.0144790152013 | 0.4 | PARP4 MVP | 16p11 2 proximal deletion syndrome |
| REAC:R-HSA-2022090 | 0.0163316506439 | 0.4 | COL4A6 COL12A1 | Assembly of collagen fibrils and other multimeric structures |
| REAC:R-HSA-1442490 | 0.0177620315324 | 0.4 | COL4A6 COL12A1 | Collagen degradation |
| REAC:R-HSA-1650814 | 0.0200193611976 | 0.4 | COL4A6 COL12A1 | Collagen biosynthesis and modifying enzymes |
| REAC:R-HSA-1474290 | 0.0384836492499 | 0.4 | COL4A6 COL12A1 | Collagen formation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| COL8A2 | C1QTNF6 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PARP4 | MVP | 0.993 | 0.248 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| COL8A2 | COL12A1 | 0.989 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PARP4 | COL8A2 | 0.981 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COL8A2 | MVP | 0.974 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| COL4A6 | COL8A2 | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PARP4 | C1QTNF6 | 0.65 | bioplex3_WMM WMM_only | |
| MVP | C1QTNF6 | 0.629 | bioplex3_WMM WMM_only | |
| PARP4 | COL12A1 | 0.473 | 0.026 | bioplex3_WMM WMM_only |
| C1QTNF6 | COL12A1 | 0.455 | bioplex3_WMM WMM_only | |
| MVP | COL12A1 | 0.429 | 0.106 | bioplex3_WMM WMM_only |
| COL4A6 | COL12A1 | 0.418 | bioplex_WMM bioplex3_WMM WMM_only | |
| COL4A6 | C1QTNF6 | 0.063 | bioplex3_WMM WMM_only | |
| COL4A6 | PARP4 | 0.03 | bioplex3_WMM WMM_only | |
| COL4A6 | MVP | 0.028 | bioplex3_WMM WMM_only |
Related Complexes