hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08505.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GYS1 | Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1) | 5 | UniProt NCBI |
| GBE1 | 1,4-alpha-glucan-branching enzyme (EC 2.4.1.18) (Brancher enzyme) (Glycogen-branching enzyme) | 5 | UniProt NCBI |
| GYG1 | Glycogenin-1 (GN-1) (GN1) (EC 2.4.1.186) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5173 | 3.31996874241e-05 | 1.0 | GBE1 GYG1 | Disorders of galactose metabolism |
| KEGG:00500 | 4.8770908342e-05 | 1.0 | GBE1 GYG1 | Starch and sucrose metabolism |
| REAC:R-HSA-3229121 | 0.000155497319444 | 1.0 | GBE1 GYG1 | Glycogen storage diseases |
| REAC:R-HSA-3322077 | 0.000155497319444 | 1.0 | GBE1 GYG1 | Glycogen synthesis |
| WP:WP500 | 0.00028347425416 | 1.0 | GBE1 GYG1 | Glycogen synthesis and degradation |
| REAC:R-HSA-8982491 | 0.000471618243588 | 1.0 | GBE1 GYG1 | Glycogen metabolism |
| REAC:R-HSA-5663084 | 0.000743311362176 | 1.0 | GBE1 GYG1 | Diseases of carbohydrate metabolism |
| HPA:0470203 | 0.0271712885755 | 1.0 | GBE1 GYG1 | skin 2; endothelial cells[High] |
| HP:0003677 | 0.0295479082178 | 1.0 | GBE1 GYG1 | Slowly progressive |
| REAC:R-HSA-5668914 | 0.0297170756313 | 1.0 | GBE1 GYG1 | Diseases of metabolism |
| REAC:R-HSA-3828062 | 0.0499419797295 | 0.5 | GYG1 | Glycogen storage disease type 0 (muscle GYS1) |
| REAC:R-HSA-5357609 | 0.0499419797295 | 0.5 | GYG1 | Glycogen storage disease type II (GAA) |
| REAC:R-HSA-3814836 | 0.0499419797295 | 0.5 | GYG1 | Glycogen storage disease type XV (GYG1) |
| HP:0034766 | 0.0499436884913 | 0.5 | GYG1 | Muscle fiber polyglucosan inclusion bodies |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GYS1 | GBE1 | 0.978 | 0.098 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GBE1 | 0.978 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| GYG1 | GYS1 | 0.962 | 0.044 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes