hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08515.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PHF20 | PHD finger protein 20 (Glioma-expressed antigen 2) (Hepatocellular carcinoma-associated antigen 58) (Novel zinc finger protein) (Transcription factor TZP) | 5 | UniProt NCBI |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 (NSL complex protein NSL3) (Non-specific lethal 3 homolog) (Serum inhibited-related protein) (Testis development protein PRTD) | 5 | UniProt NCBI |
| MCRS1 | Microspherule protein 1 (58 kDa microspherule protein) (Cell cycle-regulated factor p78) (INO80 complex subunit J) (MCRS2) | 5 | UniProt NCBI |
| C9JHY2 | None | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7221 | 1.96449718988e-08 | 1.0 | PHF20 MCRS1 KANSL3 | NSL complex |
| REAC:R-HSA-9772755 | 4.61002915454e-06 | 1.0 | PHF20 MCRS1 KANSL3 | Formation of WDR5-containing histone-modifying complexes |
| GO:0044545 | 1.58598067776e-05 | 1.0 | PHF20 MCRS1 KANSL3 | NSL complex |
| REAC:R-HSA-3214847 | 0.00016307931474 | 1.0 | PHF20 MCRS1 KANSL3 | HATs acetylate histones |
| REAC:R-HSA-212165 | 0.000382056166183 | 1.0 | PHF20 MCRS1 KANSL3 | Epigenetic regulation of gene expression |
| GO:1902562 | 0.00110345807156 | 1.0 | PHF20 MCRS1 KANSL3 | H4 histone acetyltransferase complex |
| CORUM:5386 | 0.00110947902158 | 0.666666666667 | PHF20 MCRS1 | MLL1-WDR5 complex |
| REAC:R-HSA-3247509 | 0.00120056730917 | 1.0 | PHF20 MCRS1 KANSL3 | Chromatin modifying enzymes |
| REAC:R-HSA-4839726 | 0.00120056730917 | 1.0 | PHF20 MCRS1 KANSL3 | Chromatin organization |
| GO:0000123 | 0.0105478288276 | 1.0 | PHF20 MCRS1 KANSL3 | histone acetyltransferase complex |
| GO:0031248 | 0.0146194737676 | 1.0 | PHF20 MCRS1 KANSL3 | protein acetyltransferase complex |
| GO:1902493 | 0.0146194737676 | 1.0 | PHF20 MCRS1 KANSL3 | acetyltransferase complex |
| CORUM:1057 | 0.0499402709677 | 0.333333333333 | MCRS1 | DIPA-MCRS1 complex |
| CORUM:6314 | 0.0499402709677 | 0.333333333333 | MCRS1 | MSP58-RINT1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PHF20 | KANSL3 | 1.0 | 0.286 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| MCRS1 | PHF20 | 0.992 | 0.374 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| KANSL3 | C9JHY2 | 0.977 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| MCRS1 | KANSL3 | 0.954 | 0.332 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| MCRS1 | C9JHY2 | 0.841 | bioplex_WMM bioplex3_WMM WMM_only | |
| PHF20 | C9JHY2 | 0.245 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes