hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08527.1
Complex Portal: CPX-12488
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IVL | Involucrin | 5 | UniProt NCBI |
| S100A11 | Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed] | 5 | UniProt NCBI |
| TYMP | Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase) | 5 | UniProt NCBI |
| CRABP2 | Cellular retinoic acid-binding protein 2 (Cellular retinoic acid-binding protein II) (CRABP-II) | 5 | UniProt NCBI |
| LCN2 | Neutrophil gelatinase-associated lipocalin (NGAL) (25 kDa alpha-2-microglobulin-related subunit of MMP-9) (Lipocalin-2) (Oncogene 24p3) (Siderocalin) (p25) | 5 | UniProt NCBI |
| A2ML1 | Alpha-2-macroglobulin-like protein 1 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9) | 5 | UniProt NCBI |
| SERPINB4 | Serpin B4 (Leupin) (Peptidase inhibitor 11) (PI-11) (Squamous cell carcinoma antigen 2) (SCCA-2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0471401 | 0.000511112498752 | 0.6 | IVL SERPINB4 A2ML1 | skin 2; cells in corneal layer[>=Low] |
| HPA:0460182 | 0.000678709436793 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 1; cells in granular layer[>=Medium] |
| HPA:0470182 | 0.000683901796962 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 2; cells in granular layer[>=Medium] |
| HPA:0461412 | 0.000910592230615 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 1; cells in spinous layer[>=Medium] |
| HPA:0471412 | 0.00154572452116 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 2; cells in spinous layer[>=Medium] |
| HPA:0460181 | 0.00180973618749 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 1; cells in granular layer[>=Low] |
| HPA:0470181 | 0.00183134834989 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 2; cells in granular layer[>=Low] |
| HPA:0461413 | 0.00208397740023 | 0.6 | IVL SERPINB4 A2ML1 | skin 1; cells in spinous layer[High] |
| HPA:0461411 | 0.00251845971887 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 1; cells in spinous layer[>=Low] |
| HPA:0460183 | 0.00334812702156 | 0.6 | IVL SERPINB4 A2ML1 | skin 1; cells in granular layer[High] |
| HPA:0470183 | 0.00339144619884 | 0.6 | IVL SERPINB4 A2ML1 | skin 2; cells in granular layer[High] |
| HPA:0471413 | 0.00356842784326 | 0.6 | IVL SERPINB4 A2ML1 | skin 2; cells in spinous layer[High] |
| HPA:0471411 | 0.00412014949722 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | skin 2; cells in spinous layer[>=Low] |
| HPA:0620223 | 0.0103231962266 | 0.8 | IVL A2ML1 SERPINB4 S100A11 | vagina; squamous epithelial cells[High] |
| HPA:0461402 | 0.0115492947595 | 0.4 | A2ML1 SERPINB4 | skin 1; cells in corneal layer[>=Medium] |
| HPA:0471402 | 0.0235407341342 | 0.4 | A2ML1 SERPINB4 | skin 2; cells in corneal layer[>=Medium] |
| HPA:0461401 | 0.0254128848442 | 0.4 | A2ML1 SERPINB4 | skin 1; cells in corneal layer[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| IVL | LCN2 | 0.995 | 0.201142857143 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| IVL | A2ML1 | 0.992 | 0.22 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| A2ML1 | SERPINB4 | 0.992 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | ||
| IVL | CRABP2 | 0.991 | 0.062 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| A2ML1 | LCN2 | 0.99 | 0.25 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| IVL | SERPINB4 | 0.987 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | ||
| IVL | S100A11 | 0.968 | 0.086 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| SERPINB4 | LCN2 | 0.964 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | ||
| A2ML1 | CRABP2 | 0.961 | 0.068 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| TYMP | A2ML1 | 0.961 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| TYMP | SERPINB4 | 0.959 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | ||
| TYMP | IVL | 0.953 | 0.058 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| TYMP | CRABP2 | 0.951 | 0.034 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| CRABP2 | LCN2 | 0.942 | 0.104 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| TYMP | LCN2 | 0.922 | 0.222 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| SERPINB4 | CRABP2 | 0.834 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only | ||
| S100A11 | LCN2 | 0.766 | 0.178 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| A2ML1 | S100A11 | 0.753 | 0.052 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| S100A11 | CRABP2 | 0.753 | 0.078 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| TYMP | S100A11 | 0.535 | 0.152857142857 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM | |
| SERPINB4 | S100A11 | 0.373 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only |
Related Complexes