hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08529.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| POTEI | POTE ankyrin domain family member I | 4 | UniProt NCBI |
| LRRC20 | Leucine-rich repeat-containing protein 20 | 2 | UniProt NCBI |
| ACTBL2 | Beta-actin-like protein 2 (Kappa-actin) | 4 | UniProt NCBI |
| ACTA2 | Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form] | 5 | UniProt NCBI |
| ACTB | Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0098973 | 3.362820138e-05 | 0.6 | POTEI ACTBL2 ACTB | structural constituent of postsynaptic actin cytoskeleton |
| GO:0099186 | 0.000158467845213 | 0.6 | POTEI ACTBL2 ACTB | structural constituent of postsynapse |
| GO:0098918 | 0.000436807598019 | 0.6 | POTEI ACTBL2 ACTB | structural constituent of synapse |
| GO:0035267 | 0.00314081658857 | 0.6 | POTEI ACTBL2 ACTB | NuA4 histone acetyltransferase complex |
| GO:0043189 | 0.00314081658857 | 0.6 | POTEI ACTBL2 ACTB | H4/H2A histone acetyltransferase complex |
| WP:WP4534 | 0.00456408083355 | 0.4 | ACTB ACTA2 | Mechanoregulation and pathology of YAP TAZ via Hippo and non Hippo mechanisms |
| GO:1902562 | 0.0109904490822 | 0.6 | POTEI ACTBL2 ACTB | H4 histone acetyltransferase complex |
| HP:0100771 | 0.0121560512731 | 0.4 | ACTB ACTA2 | Hypoperistalsis |
| HP:0030914 | 0.0134337956242 | 0.4 | ACTB ACTA2 | Abnormal peristalsis |
| HPA:0031323 | 0.0188951517867 | 0.4 | ACTB ACTA2 | appendix; enterocytes - Microvilli[High] |
| HPA:0131323 | 0.0211548234951 | 0.4 | ACTB ACTA2 | colon; enterocytes - Microvilli[High] |
| HPA:0151323 | 0.0211548234951 | 0.4 | ACTB ACTA2 | duodenum; enterocytes - Microvilli[High] |
| HPA:0030433 | 0.0273558379133 | 0.4 | ACTB ACTA2 | appendix; germinal center cells[High] |
| HPA:0401323 | 0.0273558379133 | 0.4 | ACTB ACTA2 | rectum; enterocytes - Microvilli[High] |
| HPA:0481323 | 0.031453796633 | 0.4 | ACTB ACTA2 | small intestine; enterocytes - Microvilli[High] |
| HPA:0030443 | 0.031453796633 | 0.4 | ACTB ACTA2 | appendix; non-germinal center cells[High] |
| WP:WP289 | 0.0492060648012 | 0.4 | ACTB ACTA2 | Myometrial relaxation and contraction pathways |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ACTBL2 | ACTB | 0.999 | 0.684 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM |
| POTEI | ACTB | 0.997 | 0.16308 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| LRRC20 | ACTBL2 | 0.992 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ACTA2 | ACTBL2 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| ACTA2 | ACTB | 0.977 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| LRRC20 | ACTB | 0.97 | 0.062 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| LRRC20 | ACTA2 | 0.958 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LRRC20 | POTEI | 0.822 | 0.062 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| ACTA2 | POTEI | 0.338 | bioplex_WMM bioplex3_WMM WMM_only | |
| ACTBL2 | POTEI | 0.337 | 0.086 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes