hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08533.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KITLG | Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)] | 5 | UniProt NCBI |
| RPIA | Ribose-5-phosphate isomerase (EC 5.3.1.6) (Phosphoriboisomerase) | 5 | UniProt NCBI |
| COQ9 | Ubiquinone biosynthesis protein COQ9, mitochondrial | 5 | UniProt NCBI |
| TKFC | Triokinase/FMN cyclase (Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)) [Includes: ATP-dependent dihydroxyacetone kinase (DHA kinase) (EC 2.7.1.28) (EC 2.7.1.29) (Glycerone kinase) (Triokinase) (Triose kinase); FAD-AMP lyase (cyclizing) (EC 4.6.1.15) (FAD-AMP lyase (cyclic FMN forming)) (FMN cyclase)] | 5 | UniProt NCBI |
| PHPT1 | 14 kDa phosphohistidine phosphatase (EC 3.9.1.3) (Phosphohistidine phosphatase 1) (PHPT1) (Protein histidine phosphatase) (PHP) (Protein janus-A homolog) | 5 | UniProt NCBI |
| PGA4 | Pepsin A-4 (EC 3.4.23.1) (Pepsinogen-4) | 5 | UniProt NCBI |
| TIGAR | Fructose-2,6-bisphosphatase TIGAR (EC 3.1.3.46) (TP53-induced glycolysis and apoptosis regulator) (TP53-induced glycolysis regulatory phosphatase) | 5 | UniProt NCBI |
| NTNG1 | Netrin-G1 (Laminet-1) | 5 | UniProt NCBI |
| GNL1 | Guanine nucleotide-binding protein-like 1 (GTP-binding protein HSR1) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00051 | 0.00721815068089 | 0.25 | TKFC TIGAR | Fructose and mannose metabolism |
| WP:WP4290 | 0.0175479862645 | 0.25 | RPIA TIGAR | Metabolic reprogramming in colon cancer |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| COQ9 | NTNG1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PHPT1 | NTNG1 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| RPIA | NTNG1 | 0.993 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KITLG | NTNG1 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NTNG1 | GNL1 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NTNG1 | TIGAR | 0.988 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TKFC | NTNG1 | 0.975 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PGA4 | NTNG1 | 0.969 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| PHPT1 | GNL1 | 0.634 | 0.096 | bioplex3_WMM WMM_only |
| COQ9 | TIGAR | 0.634 | 0.034 | bioplex3_WMM WMM_only |
| TKFC | PHPT1 | 0.605 | 0.01 | bioplex3_WMM WMM_only |
| TKFC | COQ9 | 0.605 | 0.094 | bioplex3_WMM WMM_only |
| TKFC | GNL1 | 0.575 | 0.082 | bioplex3_WMM WMM_only |
| COQ9 | PHPT1 | 0.378 | 0.04 | bioplex3_WMM WMM_only |
| KITLG | COQ9 | 0.288 | bioplex3_WMM WMM_only | |
| TKFC | TIGAR | 0.277 | 0.036 | bioplex3_WMM WMM_only |
| KITLG | PHPT1 | 0.255 | bioplex3_WMM WMM_only | |
| RPIA | COQ9 | 0.224 | 0.034 | bioplex3_WMM WMM_only |
| KITLG | PGA4 | 0.214 | bioplex3_WMM WMM_only | |
| PHPT1 | PGA4 | 0.214 | bioplex3_WMM WMM_only | |
| COQ9 | PGA4 | 0.214 | bioplex3_WMM WMM_only | |
| KITLG | GNL1 | 0.188 | bioplex3_WMM WMM_only | |
| PHPT1 | TIGAR | 0.188 | 0.222 | bioplex3_WMM WMM_only |
| COQ9 | GNL1 | 0.188 | 0.03 | bioplex3_WMM WMM_only |
| RPIA | PGA4 | 0.182 | bioplex3_WMM WMM_only | |
| KITLG | TIGAR | 0.182 | bioplex3_WMM WMM_only | |
| RPIA | TIGAR | 0.167 | 0.032 | bioplex3_WMM WMM_only |
| RPIA | GNL1 | 0.155 | 0.038 | bioplex3_WMM WMM_only |
| KITLG | RPIA | 0.154 | bioplex3_WMM WMM_only | |
| RPIA | PHPT1 | 0.143 | 0.016 | bioplex3_WMM fraction |
| TKFC | KITLG | 0.109 | bioplex3_WMM WMM_only | |
| PGA4 | TIGAR | 0.108 | bioplex3_WMM WMM_only | |
| TKFC | RPIA | 0.084 | 0.07 | bioplex3_WMM WMM_only |
| PGA4 | GNL1 | 0.055 | bioplex3_WMM WMM_only | |
| GNL1 | TIGAR | 0.054 | 0.072 | bioplex3_WMM youn_WMM WMM_only |
| TKFC | PGA4 | 0.043 | bioplex3_WMM WMM_only |
Related Complexes