hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08542.1
Complex Portal: CPX-16303
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DOLK | Dolichol kinase (EC 2.7.1.108) (Transmembrane protein 15) | 5 | UniProt NCBI |
| KCNA6 | Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel HBK2) (Voltage-gated potassium channel subunit Kv1.6) | 5 | UniProt NCBI |
| KCNA3 | Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3) | 5 | UniProt NCBI |
| VAT1 | Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-4755583 | 0.0498224659464 | 0.333333333333 | DOLK | Defective DOLK causes DOLK-CDG |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNA6 | DOLK | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNA6 | KCNA3 | 0.985 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNA6 | VAT1 | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| DOLK | KCNA3 | 0.761 | bioplex_WMM bioplex3_WMM WMM_only | ||
| VAT1 | KCNA3 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only | ||
| VAT1 | DOLK | 0.013 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes