hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08562.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MRPS18B | Small ribosomal subunit protein mS40 (28S ribosomal protein S18-2, mitochondrial) (MRP-S18-2) (28S ribosomal protein S18b, mitochondrial) (MRP-S18-b) (Mrps18-b) (S18mt-b) (Small ribosomal subunit protein bS18b) | 5 | UniProt NCBI |
| MRPS27 | Small ribosomal subunit protein mS27 (28S ribosomal protein S27, mitochondrial) (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27) | 5 | UniProt NCBI |
| HARS2 | Histidine--tRNA ligase, mitochondrial (EC 6.1.1.21) (Histidine--tRNA ligase-like) (Histidyl-tRNA synthetase) (HisRS) | 5 | UniProt NCBI |
| MRPS2 | Small ribosomal subunit protein uS2m (28S ribosomal protein S2, mitochondrial) (MRP-S2) (S2mt) | 5 | UniProt NCBI |
| AURKAIP1 | Small ribosomal subunit protein mS38 (28S ribosomal protein S38, mitochondrial) (MRP-S38) (Aurora kinase A-interacting protein) (AURKA-interacting protein) | 5 | UniProt NCBI |
| MRPS17 | Small ribosomal subunit protein uS17m (28S ribosomal protein S17, mitochondrial) (MRP-S17) (S17mt) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5419276 | 7.30488556265e-09 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | Mitochondrial translation termination |
| REAC:R-HSA-5368286 | 7.30488556265e-09 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | Mitochondrial translation initiation |
| REAC:R-HSA-5389840 | 7.30488556265e-09 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | Mitochondrial translation elongation |
| REAC:R-HSA-72766 | 1.02245458383e-08 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | Translation |
| REAC:R-HSA-5368287 | 1.02710475482e-08 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | Mitochondrial translation |
| GO:0000314 | 1.08628542536e-08 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | organellar small ribosomal subunit |
| GO:0005763 | 1.08628542536e-08 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial small ribosomal subunit |
| CORUM:315 | 2.62425558051e-08 | 0.666666666667 | MRPS18B MRPS17 MRPS2 MRPS27 | 28S ribosomal subunit, mitochondrial |
| GO:0015935 | 9.28738723532e-07 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | small ribosomal subunit |
| CORUM:320 | 1.3587401418e-06 | 0.666666666667 | MRPS18B MRPS17 MRPS2 MRPS27 | 55S ribosome, mitochondrial |
| GO:0000313 | 2.10650266006e-06 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | organellar ribosome |
| GO:0005761 | 2.10650266006e-06 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial ribosome |
| GO:0032543 | 1.258414027e-05 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial translation |
| GO:0005759 | 2.11940672502e-05 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | mitochondrial matrix |
| GO:0140053 | 3.50374175094e-05 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial gene expression |
| GO:0044391 | 8.42001762745e-05 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | ribosomal subunit |
| GO:0006412 | 0.000118417549116 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | translation |
| GO:0043043 | 0.000141389276595 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | peptide biosynthetic process |
| GO:0005840 | 0.000173213899325 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | ribosome |
| GO:0043604 | 0.000411170968199 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | amide biosynthetic process |
| GO:0006518 | 0.000446172352959 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | peptide metabolic process |
| REAC:R-HSA-392499 | 0.000464689660191 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | Metabolism of proteins |
| GO:0098798 | 0.00080415060816 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial protein-containing complex |
| GO:0043603 | 0.00239328344874 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | amide metabolic process |
| GO:0005743 | 0.00402322779151 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial inner membrane |
| GO:0019866 | 0.00534701059771 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | organelle inner membrane |
| GO:0031966 | 0.0215578343109 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial membrane |
| GO:0005739 | 0.022429776518 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | mitochondrion |
| GO:1901566 | 0.0225352456866 | 1.0 | MRPS2 MRPS17 MRPS18B HARS2 MRPS27 AURKAIP1 | organonitrogen compound biosynthetic process |
| GO:0005740 | 0.0298219178279 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | mitochondrial envelope |
| GO:1990904 | 0.0311091592946 | 0.833333333333 | MRPS18B MRPS17 AURKAIP1 MRPS2 MRPS27 | ribonucleoprotein complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MRPS2 | MRPS18B | 0.999 | 0.914 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM Malo bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| MRPS27 | MRPS18B | 0.999 | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| MRPS27 | MRPS17 | 0.998 | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| MRPS27 | MRPS2 | 0.998 | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| MRPS17 | MRPS18B | 0.997 | 0.98 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only |
| MRPS17 | MRPS2 | 0.996 | 0.988 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM treiber_WMM |
| AURKAIP1 | MRPS2 | 0.994 | 0.586 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 treiber_WMM |
| AURKAIP1 | MRPS17 | 0.993 | 0.432 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MRPS27 | AURKAIP1 | 0.993 | 0.622 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| AURKAIP1 | MRPS18B | 0.981 | 0.502 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| HARS2 | MRPS17 | 0.975 | 0.14 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only |
| HARS2 | MRPS2 | 0.182 | 0.274 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| HARS2 | MRPS18B | 0.05 | 0.186 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM |
| MRPS27 | HARS2 | 0.014 | 0.122 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM |
Related Complexes