hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08571.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAMB3 | Laminin subunit beta-3 (Epiligrin subunit bata) (Kalinin B1 chain) (Kalinin subunit beta) (Laminin B1k chain) (Laminin-5 subunit beta) (Nicein subunit beta) | 5 | UniProt NCBI |
| TOR3A | Torsin-3A (ATP-dependent interferon-responsive protein) (Torsin family 3 member A) | 5 | UniProt NCBI |
| OMA1 | Metalloendopeptidase OMA1, mitochondrial (EC 3.4.24.-) (Metalloprotease-related protein 1) (MPRP-1) (Overlapping with the m-AAA protease 1 homolog) | 5 | UniProt NCBI |
| PCSK9 | Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-) (Neural apoptosis-regulated convertase 1) (NARC-1) (Proprotein convertase 9) (PC9) (Subtilisin/kexin-like protease PC9) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2846 | 0.0248784837172 | 0.25 | PCSK9 | PCSK9 mediated LDL receptor degradation |
| WP:WP3408 | 0.0248784837172 | 0.25 | PCSK9 | Evolocumab mechanism to reduce LDL cholesterol |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TOR3A | OMA1 | 0.987 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| LAMB3 | TOR3A | 0.978 | 0.02 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| PCSK9 | TOR3A | 0.968 | 0.036 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| LAMB3 | PCSK9 | 0.443 | 0.12 | bioplex3_WMM WMM_only |
| PCSK9 | OMA1 | 0.008 | 0.08 | bioplex3_WMM WMM_only |
| LAMB3 | OMA1 | 0.008 | 0.03 | bioplex3_WMM WMM_only |
Related Complexes