hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08607.1
Complex Portal: CPX-15814
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SGO1 | Shugoshin 1 (Serologically defined breast cancer antigen NY-BR-85) (Shugoshin-like 1) | 5 | UniProt NCBI |
| WDR20 | WD repeat-containing protein 20 (Protein DMR) | 5 | UniProt NCBI |
| FERMT2 | Fermitin family homolog 2 (Kindlin-2) (Mitogen-inducible gene 2 protein) (MIG-2) (Pleckstrin homology domain-containing family C member 1) (PH domain-containing family C member 1) | 5 | UniProt NCBI |
| PHLPP1 | PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP) | 5 | UniProt NCBI |
| USP12 | Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6634 | 4.09448956317e-05 | 0.4 | WDR20 USP12 | WDR20-USP12-UAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| WDR20 | FERMT2 | 0.999 | 0.186 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| WDR20 | USP12 | 0.994 | 0.152 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| SGO1 | USP12 | 0.981 | 0.108 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SGO1 | WDR20 | 0.969 | 0.086 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PHLPP1 | WDR20 | 0.967 | 0.118 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PHLPP1 | FERMT2 | 0.675 | 0.256 | bioplex3_WMM WMM_only | |
| FERMT2 | USP12 | 0.399 | 0.084 | bioplex3_WMM gupta_WMM WMM_only | |
| PHLPP1 | USP12 | 0.267 | 0.054 | bioplex3_WMM WMM_only |
Related Complexes