hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08611.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHPF2 | Chondroitin sulfate glucuronyltransferase (EC 2.4.1.226) (CSGlcA-T) (Chondroitin glucuronyltransferase) (Chondroitin polymerizing factor 2) (ChPF-2) (Chondroitin synthase 3) (ChSy-3) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase) | 5 | UniProt NCBI |
| CHSY3 | Chondroitin sulfate synthase 3 (EC 2.4.1.175) (EC 2.4.1.226) (Carbohydrate synthase 2) (Chondroitin glucuronyltransferase 3) (Chondroitin synthase 2) (ChSy-2) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 3) (N-acetylgalactosaminyltransferase 3) | 5 | UniProt NCBI |
| TIMP3 | Metalloproteinase inhibitor 3 (Protein MIG-5) (Tissue inhibitor of metalloproteinases 3) (TIMP-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00532 | 0.000144921335192 | 0.666666666667 | CHPF2 CHSY3 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |
| WP:WP5395 | 0.00079501095268 | 0.666666666667 | CHPF2 CHSY3 | Glycosaminoglycan synthesis in fibroblasts |
| REAC:R-HSA-2022870 | 0.000926675585137 | 0.666666666667 | CHPF2 CHSY3 | Chondroitin sulfate biosynthesis |
| REAC:R-HSA-1793185 | 0.00704293704569 | 0.666666666667 | CHPF2 CHSY3 | Chondroitin sulfate/dermatan sulfate metabolism |
| GO:0050510 | 0.00842684400117 | 0.666666666667 | CHPF2 CHSY3 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity |
| GO:0047238 | 0.0210651876021 | 0.666666666667 | CHPF2 CHSY3 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity |
| REAC:R-HSA-1630316 | 0.0406752460979 | 0.666666666667 | CHPF2 CHSY3 | Glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CHPF2 | TIMP3 | 0.964 | 0.124 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| CHPF2 | CHSY3 | 0.961 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| TIMP3 | CHSY3 | 0.069 | bioplex3_WMM WMM_only |
Related Complexes