hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08612.1
Complex Portal: CPX-21829
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DAD1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (Oligosaccharyl transferase subunit DAD1) (Defender against cell death 1) (DAD-1) | 5 | UniProt NCBI |
| DDOST | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (DDOST 48 kDa subunit) (Oligosaccharyl transferase 48 kDa subunit) | 5 | UniProt NCBI |
| LMF2 | Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153) | 4 | UniProt NCBI |
| STT3B | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B (Oligosaccharyl transferase subunit STT3B) (STT3-B) (EC 2.4.99.18) (Source of immunodominant MHC-associated peptides homolog) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1200 | 2.45511732198e-08 | 0.75 | STT3B DAD1 DDOST | Oligosaccharyltransferase complex (Stt3B variant) |
| KEGG:00513 | 3.38522311544e-06 | 0.75 | STT3B DAD1 DDOST | Various types of N-glycan biosynthesis |
| KEGG:00510 | 5.92375820233e-06 | 0.75 | STT3B DAD1 DDOST | N-Glycan biosynthesis |
| WP:WP5153 | 7.26097531109e-06 | 0.75 | STT3B DAD1 DDOST | N glycan biosynthesis |
| GO:0008250 | 6.34131776058e-05 | 0.75 | STT3B DAD1 DDOST | oligosaccharyltransferase complex |
| CORUM:1199 | 7.68662167609e-05 | 0.5 | DAD1 DDOST | Oligosaccharyltransferase complex (Stt3A variant) |
| KEGG:04141 | 0.000211376960202 | 0.75 | STT3B DAD1 DDOST | Protein processing in endoplasmic reticulum |
| GO:0018279 | 0.000591522022343 | 0.75 | STT3B DAD1 DDOST | protein N-linked glycosylation via asparagine |
| REAC:R-HSA-9694548 | 0.006081926491 | 0.5 | DAD1 DDOST | Maturation of spike protein |
| GO:0006487 | 0.0131184183431 | 0.75 | STT3B DAD1 DDOST | protein N-linked glycosylation |
| REAC:R-HSA-9694635 | 0.0140623832262 | 0.5 | DAD1 DDOST | Translation of Structural Proteins |
| REAC:R-HSA-9772573 | 0.019281632575 | 0.5 | DAD1 DDOST | Late SARS-CoV-2 Infection Events |
| HP:0012345 | 0.0375654511359 | 0.5 | STT3B DDOST | Abnormal glycosylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DDOST | STT3B | 0.998 | 0.906 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| DAD1 | STT3B | 0.977 | 0.83 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
| STT3B | LMF2 | 0.961 | 0.194 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| DDOST | DAD1 | 0.155 | 0.948 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| DDOST | LMF2 | 0.076 | 0.272 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| DAD1 | LMF2 | 0.037 | 0.196 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
Related Complexes